Estradiol 112,5 pmol/l - should I be concerned?

[KingOfSofia]

So, I posted in the wrong section today, a big sorry to the moderators. I got my blood tests and although everything is in the reference values, people around me have made me concerned about my estradiol levels. My last cycle was 2 years ago (I have 3 cycles all in all, all with PCT).
The results are:


Estradiol: 112,5 pmol/l reference values - 28-156
Testosterone : 17,96 nmol/l reference values - 9,9 - 27,8

So, people that have done AAS are telling me that my estradiol is high, it should be in the lower side of the reference values, or under 100. Is this broscience or should I be concerned? If I should be, what would be the next step to lower it? I would probably visit my doctor next week with the results, but I want to hear your opinion because most doctors locally do not have knowledge about steroids and their effects.

[KingOfSofia]

It seems most of the articles on the net use pg/ml instead of pmol/l. I have been researching, and in order to convert, I should divide by 3,671 to get pg/ml. I get 30,7 pg/ml and from what I am reading this is ok. Could somebody confirm this, because I do not have enough knowledge to trust myself with that.
I forgot to mention I am 26 years old.

[fit2bOld]

According to the reference range of your blood work it is in the high end. Most of the guys on the forum seem to run middle to lower in the reference range. You haven't mentioned anything about how you feel or any side effects that you could be experiencing.
Do you have a full hormone panel of blood work to post or was that all you had done.
Do you do proper PCT after you last cycle?

Most important is that you get yourself squared away so you don't have to be a long term member of the HRT section.

[steroid.com 1]

If your math is correct 30.7 pg/ml is fine.

Why did you check?

Any symptoms?

[Vettester]

King, your math is correct, and as GD stated, your 30.7 pg/ml is fine.

Just so you know, your total serum converted to ng/dl is 517. I'd be curious what your free and bio test numbers?

[oscarjones]

The "optimal" level of Estradiol will deviate from man to man. Some find 25-30 a very healthy range where they feel the best they can, and others find it that jumps 5-10 points in either direction, the optimism changes.

I say, if you feel good, and your labs are solid, don't change anything.

[KingOfSofia]

Thanks for taking the time to answer me, guys. I got full bloodwork done (as full as it can be around here), but this does not include free test and bio test. I am in the process of searching for a lab that offers such tests, but it is not a easy task locally. The rest of the hormones I could get tested gave this results:

FT3 5,22 pmol/l Ref: 3,10-6,80
FT 4 17,27 pmol/l Ref: 12-22
TSH 1,920 mIU/l Ref: 0,27 - 4,2

Prolactin 241,40 mIU/l Ref: 86 - 324
Progesteron 2,34 nmol/l Ref: 0,7 - 4,3

There was no particular reason for the blood test, just to see where I am at. I feel fine, the only side effect that I still get seems to be acne. Since I did AAS cycles, I am much more acne-prone. It is not something big, just a pimple here and there, but still - it was not like this before that.
I have always tried to do proper PCT, the info for it was taken and discussed in this forum, so I think it was ok.

How do you control your estradiol when not on cycle? Do you start arimidex, for how long, etc? If I have to go this way, I would actually have to get the info from here, I do not know a good doctor locally that has got knowledge in this matter like you guys.

[oscarjones]

Thanks for taking the time to answer me, guys. I got full bloodwork done (as full as it can be around here), but this does not include free test and bio test. I am in the process of searching for a lab that offers such tests, but it is not a easy task locally. The rest of the hormones I could get tested gave this results:

FT3 5,22 pmol/l Ref: 3,10-6,80
FT 4 17,27 pmol/l Ref: 12-22
TSH 1,920 mIU/l Ref: 0,27 - 4,2

Prolactin 241,40 mIU/l Ref: 86 - 324
Progesteron 2,34 nmol/l Ref: 0,7 - 4,3

There was no particular reason for the blood test, just to see where I am at. I feel fine, the only side effect that I still get seems to be acne. Since I did AAS cycles, I am much more acne-prone. It is not something big, just a pimple here and there, but still - it was not like this before that.
I have always tried to do proper PCT, the info for it was taken and discussed in this forum, so I think it was ok.

How do you control your estradiol when not on cycle? Do you start arimidex, for how long, etc? If I have to go this way, I would actually have to get the info from here, I do not know a good doctor locally that has got knowledge in this matter like you guys.

Your prolactin is a bit high and this is a sign that your estrogen might be as well. Anastrozole or aromasin will respectfully lower your estradiol and subsequently help reduce production of prolactin. However, at this point you may need both a dopamine agonist coupled with an aromatase inhibitor to get both prolactin and estrogen down.

I would recommend like 0.5-1mg of anastrozole a week and around 0.25-0.5mg of cabergoline to help control the prolactin and estrogen, however I haven't actually seen your estrogen labs, I am assuming they are high based on prolactin production and your sides of acne.

[steroid.com 1]

Your prolactin is a bit high and this is a sign that your estrogen might be as well. Anastrozole or aromasin will respectfully lower your estradiol and subsequently help reduce production of prolactin. However, at this point you may need both a dopamine agonist coupled with an aromatase inhibitor to get both prolactin and estrogen down.

I would recommend like 0.5-1mg of anastrozole a week and around 0.25-0.5mg of cabergoline to help control the prolactin and estrogen, however I haven't actually seen your estrogen labs, I am assuming they are high based on prolactin production and your sides of acne.

Oscar - Are you a Physician?

If so, I know you'd be very careful about prescribing on a forum like this.

If not, please be very careful about recommending a pharmaceutical remedy (now including Cabergoline coupled with an AI) as there are a lot of men who read here and who are not members and can use it to possible harm without proper medical supervision and if you are not a MD you can probably understand the concern.

Also, it's almost impossible to make these kinds of recommendations without having a more complete physical and comprehensive blood work done.

Your heart is in the right place; just a word of caution is all.

Thank you.

gd

[KingOfSofia]

Thanks for that, it it some nice info to compare to the doctor's solution. My estradiol labs are
Estradiol: 112,5 pmol/l reference values - 28-156, which converted is 30,7 pg/ml with ref: 7,62 - 42,5. Is there any other estrogen test I should be start looking for (this lab had only this, and it is the most popular one ).
How long would you take caber to reduce permanently prolactin to optimum levels? I know blood tests would give that answer, so just an estimation, but it would be something to compare to the doctor's recommendation, if he prescribes caber at all. I have suffered in the past because of the doctors giving too short or too long period of using a drug, so I like to do my homework now.

[oscarjones]

Oscar - Are you a Physician?

If so, I know you'd be very careful about prescribing on a forum like this.

If not, please be very careful about recommending a pharmaceutical remedy (now including Cabergoline coupled with an AI) as there are a lot of men who read here and who are not members and can use it to possible harm without proper medical supervision and if you are not a MD you can probably understand the concern.

Also, it's almost impossible to make these kinds of recommendations without having a more complete physical and comprehensive blood work done.

Your heart is in the right place; just a word of caution is all.

Thank you.

gd

No, I am not an M.D. however I am a registered nurse and I can't help but find myself with an equivocal attitude after reading this response. I was in the wrong for suggesting medication and doses especially without prior medical history, however I will elucidate that anything I say should be taken with a grain of salt, and of course discussed with your physician before any attempt is made at commencing any therapy whatsoever. (Although there are numerous guys that do so through self-venture).