Clen with PCT ????

[starrookie6]

Can you run clen along with a PCT of Tamox/Clomid at the same time ????

[ironbeck]

Yes you can.

[t-dogg]

Yes, but i would not lower calories on pct thought.

[tballz]

Clenbuterol is a long acting, selective beta 2 receptor agonist. So let’s take a look at what that means. Long acting is fairly self-explanatory. Selective means it targets specific beta receptor sites. The beta 2 receptor is responsible for several things but is heavily present in the respiratory system. An agonist (in this case) is a substance that bonds to the receptor of a cell triggering some form of response, quite often it mimics a naturally occurring substance with the organism.
So let’s put that all together. Clenbuterol bonds to the beta 2 receptor and triggers a response. So what is that response? Well beta 2 receptor activation results in the production of cyclic adenosine monophosphate (cAMP). CAMP then results in an activation of protein kinease A (PKA). PKA has several functions including sugar metabolism, lipid metabolism, and glycogen regulation. Also beta 2 activation results in a decrease in intracellular calcium and an increase in potassium flow (Perhaps why in our research we may observe cramping?)
So all that sounds great and we could go very in depth with how these reactions occur to an even more minute level but let’s focus on what this beta 2 receptor activation ultimately does. Ultimately there are several effects that occur from this beta 2 receptor activation:

1: Blood vessel dilation (relaxation of smooth muscle)
2: Bronchodilation
3: Increase in metabolic activity
4: Increase in core temperature
5: Increase in basal metabolic rate

These effects provide some interesting results in our research.

1: It has been found that clenbuterol has the unique ability to preserve muscle in a state of caloric deficit while increasing the metabolism of fat.
2: It was also observed that clenbuterol has the ability to reverse muscle wasting.
3: In addition it has been shown in research to improve body composition.

To wrap it up it appears that in a research setting that clenbuterol markedly increases fat loss, decreases muscle wasting, and provides to some degree an anabolic response. An interesting substance for our research to be sure.



REFS:
*Hallows KR, Alzamora R, Li H, et al. (April 2009). Am. J. Physiol., Cell Physiol. 296 (4):C672–81. PMID 19211918.

*The effect of clenbuterol on body composition in spontaneously eating tumour-bearing mice.
Hyltander A, Svaninger G, Lundholm K. Biosci Rep. 1993 Dec;13(6):325-31. PMID: 8204802

*Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation Johnson M. J Allergy Clin Immunol. 2006 Jan;117(1):18-24; quiz 25. Review. PMID: 16387578
*Beta 2-agonist administration reverses muscle wasting and improves muscle function in aged rats. Ryall JG, Plant DR,Gregorevic P, Sillence MN, Lynch GS. J Physiol. 2004 Feb 15;555(Pt 1):175-88. Epub 2003 Nov 14. PMID: 14617677
*Effect of a selective beta 2-adrenergic agonist (clenbuterol) on energy balance and body composition in normal and protein deficient rats. Rothwell NJ, Stock MJ. Biosci Rep. 1987 Dec;7(12):933-40. PMID:3453750

Clen with pct is a good idea........

[BR0DIE]

Is it a good idea because it has anti-catabolic properties?

I've thought about running 50mcg for the first 2 weeks of PCT for this reason.

[BBJT200]

Have you ever used clen before?

This is what I've done in my research. I found my rat to have a high tolerance to the side effects, due to previous stimulant use. In my first trial my rat jumped to 120mcg on day 5. Slight shakes, but the next day nothing. From then on I just watched my rat's HR during exercise.

From then on, I've just used 120mcg daily in my research, along with ketofen after day 12. (2 doses of 60mcg split up. Before morning cardio, and after I get back or 2-3hrs later)

[t-dogg]

Body temperature should be watched as well.

[ScotchGuard02]

I hate the way clen makes me feel. I love the way it makes me look.

[marcus300]

I use to use it a lot especially in pct. Helps you to hold onto tissue at a time when your need it the most. Great addition and works well.

Ar-r is s good place to get it from

[Metalject]

Not that Clen with PCT will hurt anything but the anabolic properties of it have been proven false several times over. Or more accurately, when the anabolic claim was made it was due to the original testing being done on rats. The rats given Clenbuterol displayed an enormous amount of anabolic activity. However, it doesn't appear to translate in human beings.

[Metalject]

Yes, but i would not lower calories on pct thought.

Depends on the person. Some people have to decrease their calories during PCT. If not, they'll gain a lot of unwanted body fat. Without the exogenous hormonal support, a lot of guys cannot maintain the same caloric intake off-cycle. I'm one of those guys.

[evander87]

Depends on the person. Some people have to decrease their calories during PCT. If not, they'll gain a lot of unwanted body fat. Without the exogenous hormonal support, a lot of guys cannot maintain the same caloric intake off-cycle. I'm one of those guys.

Are you a blast and cruise kinda guy or do you come completely off after cycle? If you come completely off how do you keep gains with a calorie deficit during PCT?

[t-dogg]

Depends on the person. Some people have to decrease their calories during PCT. If not, they'll gain a lot of unwanted body fat. Without the exogenous hormonal support, a lot of guys cannot maintain the same caloric intake off-cycle. I'm one of those guys.

So you cant make yourself eat? Or that you gain fat? Confused.

[Metalject]

Are you a blast and cruise kinda guy or do you come completely off after cycle? If you come completely off how do you keep gains with a calorie deficit during PCT?

A few things:

1. I didn't say you had to be in a calorie deficit. I'm saying some people need to drop their total caloric intake down from where it was while on cycle. Without the added hormonal support, fat gain becomes much easier when you're consuming excess calories.

2. Everyone always talks about "keeping gains" but that is such a strong general statement. In my years, the vast majority of the gear I used was when dieting. Yes, I used gear in the off-season too but far more during contest prep and things like that. So at this stage, when you come off it's not about protecting a butt load of muscle mass you just gained, it's about letting your body normalize. A lot of guys end up putting on so much unnecessary fat after a hard diet like this...I've done it myself...you really have to be careful and smart when coming off gear with your diet after a cutting run of a contest caliber.

3. For several years I ran 2-3 cycles per year, PCT in-between and all that. Then for 3-4yrs I was pretty much on something non-stop...big cycles, cruise on 200mg/wk of test, repeat. Currently, the last couple years I run my TRT script and nothing more.

[Metalject]

So you cant make yourself eat? Or that you gain fat? Confused.

It doesn't have anything to do with a lack of hunger...I've never had a hard time eating. If I run a big cycle, come off and keep my caloric intake the same, I will gain body fat each and every time.

[Super-Chump]

Hi-jacking...

In a standard 4 week PCT (nolva 40/40/20/20 + clomid 100/100/50/50) what dosages are recommended to just help preserve the muscle tissue?
Also, if I were to only use the clen for 2 weeks during the pct (this is assuming I can't get any keto) which of the two weeks should I choose?