Accutane - Don't use it. You will regret it, and here's why

[BBJT200]

Accutane is a nasty drug. Sure, it will clear up the worst cases of cystic nodular acne, but at quite a price.

I took the stuff at age 16.
At age 17, I developed mild E.D. and partial loss of sensation in my genitals. I didn't think much of it, my doctor just told me it was in my head.

I'm now almost 21. In the past year, i've developed tons of the symptoms of crohns disease, completely lost my libido and ability to get a full erection, and am depressed all the time. These are all reported symptoms of post accutane use. There are tons and tons of lawsuits out there, and i'm planning on working with a doctor and a lawyer very soon. This has made my life almost not worth living. I can't enjoy sex, I'm exhausted all the time, I have low T because of it, and I've got diarrhea and lower abdominal pain every time I eat. Sound fun? DON'T TAKE ACCUTANE.

http://www.topix.com/forum/drug/accu...80HU3ALCDO04BL
This is a page with personal reviews by users as well as doctors.

I will add more as I do more research. I just want you guys to be warned. This stuff is nothing to joke around with. I would trade my old pizza face for these symptoms in a heartbeat.

[DanB]

Sorry to hear that, but if what you say is true then you 1/100,000

Accutane greatly improved my quality of life, i cant and wont cycle without it and i know countless people, staff here and friends locally who feel the same

[austinite]

Sorry about your results. I don't use it myself, but Gixxer has... with no problems. Several guys at my gym, too. No issues there either.

[Bonaparte]

What dose were you on?

[BBJT200]

Sorry about your results. I don't use it myself, but Gixxer has... with no problems. Several guys at my gym, too. No issues there either.

How long ago was their use? I didn't have extremely noticeable symptoms until over three years later. I had mild symptoms following use, but not bad enough to diagnose or pinpoint to the accutane.

Sorry to hear that, but if what you say is true then you 1/100,000

Accutane greatly improved my quality of life, i cant and wont cycle without it and i know countless people, staff here and friends locally who feel the same

I hope you never develop symptoms. From what i've been reading, they're usually slow to develop but most people will get them with time. What dosages have you taken and how long ago did you start?

What dose were you on?

80mg/day.

[binsser]

maybe it was u were too young to be using it ?? it is a very harsh drug and ur right to be ueing because of it your body was too young for it for sure!

[DanB]

I was on it with a derma at 13 at 40-60mg day and now run 10mg sometimes 20mg nearly all.year around

You one of the unlucky ones, dont try knock it for everybody based on your experience because to be honest, it sounds like bullshit......

Most people get your claimed side effects with time? That is one example i base my opinion of bullshit on

It a miracle drug for 99.9% of users

Keep researching like you claim you are and you shall see this

[poppz]

I'm on 40 mg. A day. Hope that's enough to clear up pct acne without probs

[Swifto]

80mg/day.

Which is a large dose. 10mg/ED is often enough to clear acne. There is even data on 10-20mg PER WEEK.

I don't like this thread, it just scaremoungering tactics due to your results. You're one in hundreds of thousands that have adverse side effects to Isotretinion. It works for millions of people worldwide and works very well at that. Were you monitored by a dermatologist and doctor during your course?


Why don't you go the full length and scare all the newbies into not using Isotretinion (Accutane) and state it also increases instances of suicide and "you may become suicidal"?

[Swifto]

Accutane is a nasty drug. Sure, it will clear up the worst cases of cystic nodular acne, but at quite a price.

I took the stuff at age 16.
At age 17, I developed mild E.D. and partial loss of sensation in my genitals. I didn't think much of it, my doctor just told me it was in my head.

I'm now almost 21. In the past year, i've developed tons of the symptoms of crohns disease, completely lost my libido and ability to get a full erection, and am depressed all the time. These are all reported symptoms of post accutane use. There are tons and tons of lawsuits out there, and i'm planning on working with a doctor and a lawyer very soon. This has made my life almost not worth living. I can't enjoy sex, I'm exhausted all the time, I have low T because of it, and I've got diarrhea and lower abdominal pain every time I eat. Sound fun? DON'T TAKE ACCUTANE.

http://www.topix.com/forum/drug/accu...80HU3ALCDO04BL
This is a page with personal reviews by users as well as doctors.

I will add more as I do more research. I just want you guys to be warned. This stuff is nothing to joke around with. I would trade my old pizza face for these symptoms in a heartbeat.

Your low T symptoms can be corrected with HRT. I suggest you look into it. I wouldn't have low labido, energy levels or "not enjoy sex" and suffer from ED. I did for about 2 weeks once when coming off a long cycle - never again.

[gixxerboy1]

How long ago was their use? I didn't have extremely noticeable symptoms until over three years later. I had mild symptoms following use, but not bad enough to diagnose or pinpoint to the accutane.

i used it the first time prescribed by a derm probably 13 years ago.
I have used it on my one many times through out the years. Last time was this year. On cycle use i do 20mg every 3rd day if that much

[Sgt. Hartman]

I've never had the need to use it thank god but i can thi.k of at leadt a dozen people i know off the top of my head who've used it for years w/o issues.

How bad was your acne that you were prescribed 80mg?

[BBJT200]

I've never had the need to use it thank god but i can thi.k of at leadt a dozen people i know off the top of my head who've used it for years w/o issues.

How bad was your acne that you were prescribed 80mg?

I had marble size lumps under my skin. They were very painful and ugly to look at.

[binsser]

ive heard by my source because i almost used it once that it causes alot of suicidle thoughts in men is this true i ask my source and he said are you sure you want to use it mate it is nasty stuff??? went out in the sun for a day and cleared the lot up and havent come back its been a while now so all is good but havent heard any good thing s about it to be honest ie = chapped bleeding lips - bleeding noses - depression- dry cracking skin ?? i mean really if it was that bad it would be readily avalible would it??

[gixxerboy1]

alot of the side effects are dose related too.

[binsser]

thought that ...the highest ive heard is 40mg so is 80 far too much too cause damage you cant come back from and give issues the op has gone though ??

[poppz]

I'm on 40 mg a day generic accutane... I only have a month and two weeks supply.. can someone tell me if I need more, does this only clear up what I have now or does t help with future cycles ??

[Thunderforge]

I'm on 40 mg a day generic accutane... I only have a month and two weeks supply.. can someone tell me if I need more, does this only clear up what I have now or does t help with future cycles ??

Hi poppz. I have extensive experience with accutane as well and have nothing but positive things to say. At 42 years old I have been on doctor prescribed Accutane three times. The first being at age 16. I too have suffered. Deep nodular acne that absolutely nothing else effected. Accutane removed it completely for years. Possibly curing it entirely except for a pro hormone I took in my early 30s and the gear I started recently.

To answer your questions. Google accutane dosage to get more info but 80 ng a day is not an unduly high amount for someone with nodular acne. Dose is dependent on weight. 1mg/kg. So a 200 pound person would be on approximately 90 mg a day. Treatment can run from 4-6 months.

[binsser]

interesting??

So you never had chapped lips or nose bleeds or anything from this??

[Thunderforge]

interesting??

So you never had chapped lips or nose bleeds or anything from this??

Oh most definitely chapped lips, very dry skin, dry sinuses, yes, all that. But understand we're also talking about treatment for a very severe, scarring condition. Those are the ONLY side effects I have ever suffered. All controllable with otc lotion and Carmex. The dry sinus was really only an issue the first time.

Very worth it to me.

[Swifto]

You should exhaust other avensues first, yes. But to claim you should not use Accutane is ridiculous and extreme. Oftein its the ONLY medication that will clear acne.

You must, though, get BW done on it, not drink alcohol or be exposed to the sun often. BE needs to be done every 4-5 weeks as it will play havoc on your lipid profile and liver.

I can now use it for 3-4 weeks and it clear my acne. Once its been used for a long peroid, shoter durations are far more effective. It can also be used on cycle at a low dose WITH BW.

DO NOT get a girl pregnant when on it also. Women should also not be on it, or have been on it for months/years before trying to a baby as its use it linked to child deformaties and other serious health implications.

It can be very destructive in some, but this is rare.

[Swifto]

I will also add that micronized Accutane seems to have a better safety profile than standard Accutane.


J Am Acad Dermatol. 2001 Aug;45(2):196-207.

Safety of a new micronized formulation of isotretinoin in patients with severe recalcitrant nodular acne: A randomized trial comparing micronized isotretinoin with standard isotretinoin.

Strauss JS, Leyden JJ, Lucky AW, Lookingbill DP, Drake LA, Hanifin JM, Lowe NJ, Jones TM, Stewart DM, Jarratt MT, Katz I, Pariser DM, Pariser RJ, Tschen E, Chalker DK, Rafal ES, Savin RP, Roth HL, Chang LK, Baginski DJ, Kempers S, McLane J, Eberhardt D, Leach EE, Bryce G, Hong J.
Source

Department of Dermatology, University of Iowa Health Care, Iowa City, IA 52242-2090, USA.
Abstract

BACKGROUND:

Isotretinoin is a very effective drug for treating severe recalcitrant nodular acne. A new micronized formulation of isotretinoin has been shown to be clinically equivalent to standard isotretinoin with improved bioavailability and minimal food effect. The safety profile of the micronized formulation has not been described previously.

OBJECTIVE:

The objective of this article is to report the incidence and intensity of adverse events found in a comparative, double-blind efficacy study that showed clinical equivalence of the new micronized formulation of isotretinoin and the standard isotretinoin formulation (Accutane).

METHODS:

Six hundred patients with severe recalcitrant nodular acne were treated with micronized isotretinoin (n = 300) under fasted conditions or standard isotretinoin (n = 300) under fed conditions. One cohort received single daily doses of 0.4 mg/kg of micronized isotretinoin without food and the other cohort received 1.0 mg/kg per day of standard isotretinoin in two divided doses with food. Adverse events were monitored during 20 weeks of drug therapy.

RESULTS:

The proportion of adverse events in most body systems was generally lower in patients receiving micronized isotretinoin than in those receiving standard isotretinoin.

CONCLUSION:

Micronized isotretinoin appears to have a safety profile similar to that of standard isotretinoin and to carry a lower risk of mucocutaneous events and hypertriglyceridemia.



As for its efficiency compared to standard Accutane, read on...



J Am Acad Dermatol. 2001 Aug;45(2):187-95.

A randomized trial of the efficacy of a new micronized formulation versus a standard formulation of isotretinoin in patients with severe recalcitrant nodular acne.

Strauss JS, Leyden JJ, Lucky AW, Lookingbill DP, Drake LA, Hanifin JM, Lowe NJ, Jones TM, Stewart DM, Jarratt MT, Katz I, Pariser DM, Pariser RJ, Tschen E, Chalker DK, Rafal ES, Savin RP, Roth HL, Chang LK, Baginski DJ, Kempers S, McLane J, Eberhardt D, Leach EE, Bryce G, Hong J.
Source

Department of Dermatology, University of Iowa Health Care, Iowa City, IA 52242-1090, USA.
Abstract

BACKGROUND:

Isotretinoin is very frequently the drug of choice for the management of severe recalcitrant nodular acne. Recently, a new micronized and more bioavailable formulation of isotretinoin has been developed that permits once-daily administration in lower doses than usually used with standard isotretinoin (Accutane), regardless of whether it is taken with or without food.

OBJECTIVE:

Our purpose was to determine whether micronized isotretinoin and standard isotretinoin are clinically equivalent.

METHODS:

In this multicenter, double-blind, double-dummy study, 600 patients with severe recalcitrant nodular acne were treated with either 0.4 mg/kg of micronized isotretinoin once daily without food (n = 300) or 1.0 mg/kg per day of standard isotretinoin in two divided doses with food (n = 300). Lesion counts were monitored over 20 weeks.

RESULTS:

Both treatment groups in this well-controlled clinical trial experienced an equivalent reduction in the number of total nodules (facial plus truncal). In addition, an equivalent proportion of patients achieved 90% clearance of the total number of nodules. Both formulations had similar results for other efficacy variables.

CONCLUSION:

Once-daily use of the micronized and more bioavailable formulation of isotretinoin under fasted conditions is clinically equivalent to the standard twice-daily formulation under fed conditions in the treatment of severe recalcitrant nodular acne.

[poppz]

So I guess I need a few months more to order.thnx

[Beroo]

How old should you be to use accutane? And after it treats your acne can you discontinue using it?

[poppz]

How old should you be to use accutane? And after it treats your acne can you discontinue using it?

I was trying to get an answer for that also... I had someone tell me after his accutane treatment he never had probs again.

[BBJT200]

I haven't ever had acne problems since, but I've had other health problems linked to its use.
There are tons of lawsuits out there regarding accutane injury. If you guys want to use it...I guess that's your decision. My goal here was to warn everyone of the possibility of problems afterwards. Mind you, I couldn't have made the drug-side effect connection until over three years later.

I had bleeding, cracked lips. I shaved dead skin off of my face in the morning. I couldn't go outside much, and had all of the classic 'dry skin' side effects. I'm not complaining about those--they were to be expected.

[Swifto]

How old should you be to use accutane? And after it treats your acne can you discontinue using it?

It is prescribed to 16 years old+ in my experience. However, due to its possible nasty sides and it can also lower testosterone levels, should be avoided when young IMO. Try Vit B5 at high doses first, such as 3-4g/ED.

Yes, once the user finishes accutane, it can mean they do not get acne again or anywhere near as bad as previously. Accutane seems to have a permanent effect in some, but it needs to be used for long enough 4-6months+ for this. I had terrible acne during my first and second cycle, then did a Accunate cycle of about 5months, now my acne is no where near as bad, but still evident at times. 10-20mg 3x week seems to clear it for me and choose the right androgens and doses.