
Originally Posted by
Ewit
I replied on this:
Testosterone increases Dopamine in the brain and we hear men all the time who were once hypogonadal say that when they started their TRT protocols they "never felt better in years and their libido is through the roof"!
So, testosterone replacement in hypogonadal men initially will increase sex drive, reduces depression and gives pleasure to many activities. But it's short lived unfortunately as the brain (Dopamine receptors) settles down to the now normal physiological Dopamine levels
The problem is that Dopamine is a very fragile neurotransmitter/hormone in its effect on the brain.