Would someone be kind enough to send a legit link with the halflives og AA's?
Thank you.
New Member
Would someone be kind enough to send a legit link with the halflives og AA's?
Thank you.
Banned
I have not had a chance to verify all of these. So if anyone sees something that is incorrect, please feel free to speak up. We'll correct them together once and for all.
Steroid Half life's
Anyone new to steroids may be wondering what this means, even some experienced steroid users may also be wondering what this means. So here in simple terms you can read and hopefully understand all about steroid half life's and what this term means.
Basically every drug has a half life, steroids included. If for example, you were to inject 1000mg of testosterone cypionate once weekly, for 10 weeks, how would you know when you were "off"? Would you be "off" when you had finished your last dose? You would be able to calculate this from the half life of testosterone cypionate. The half life of testosterone cypionate is around 12 days. This means that 12 days from your last shot of 1000mg of testosterone cypionate (Time to start PCT ? You decide.), your blood levels of testosterone cypionate will contain 500mg of the steroid. Another 12 days from then, i.e. 24 days from last dose, your blood levels will contain 250mg of the steroid. This amount then keeps halving every 12 days. At 48 days (almost 2 months) from your last dose, your blood levels will still contain 67.5mg of testosterone cypionate.
Therefore you can clearly see that when you finish your cycle, even though you are not putting any steroids into your body, you may think that you are now "off", however you still have, and will still have for some time after your last dose, "active" blood levels of the steroid. Therefore you can plan what to use, how long for, and how long off your cycle, based on these half life's.
Below a list of half-life's of the most commonly used steroids, esters and ancillary compounds.
**Please bare in mind that individual metabolism and other contributing factors will determine the exact length of time. These are approximate time frames.**
Oral Drug Active half-life
Anadrol / Anapolan50 (oxymetholone) 8 to 9 hours
Anavar (oxandrolone ) 9 hours
Dianabol (methandrostenolone , methandienone) 4.5 to 6 hours
Winstrol (stanozolol ) (tablets or depot taken orally) 9 hours
Depot Drug Active half-life
Deca -durabolin (Nandrolone decanate) 10.5 days
Equipoise 8 days
Finaject (trenbolone acetate) 1.5 days
Primobolan (methenolone enanthate) 5-7 days
Sustanon or Omnadren 9 days
Testosterone Cypionate 7-9 days
Testosterone Enanthate 5-7 days
Testosterone Propionate 2 days
Testosterone Suspension Less than 1 day
Masteron (Drostanolone Propionate) 2 days
Masteron Enanthate 8 days
Winstrol (stanozolol ) 1 day
Active Ester
Formate 1.5 days
Acetate 3 days
Propionate 3 days
Phenylpropionate 4.5 days
Butyrate 6 days
Valerate 7.5 days
Hexanoate 9 days
Caproate 9 days
Isocaproate 9 days
Heptanoate 10.5 days
Enanthate 14 days
Octanoate 12 days
Cypionate 18 days
Nonanoate 13.5 days
Decanoate 21 days
Undecanoate 16.5 days
Ancillaries Drug Active half-life
Aromasin (Exemestane) 10 hours
Arimidex 3 days
Clenbuterol 1.5 days
Clomid 5 days
Cytadren 6 hours
T3 2.5 days
Active Life versus Half Life
The confusion comes from the 2 terms being used synonymously when they should not be. "Half-life is not a reference for the total time a drug will be found active in the body. It may take several half-lives before the drug is completely inactive."
Half-life: The period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.
Example: The half-life of Anavar is 9 hours+/- (9 hours after oral administration of 50 mg of Anavar, 25mg is still present in the body).
Active life: Refers to the period in which the amount of a drug in the body is enough that it will still produce the desired effects for which it was administered. Or conversely, inhibit natural recovery of normal bodily function. It is dose dependent.
Example: The active life of 1,000mg of testosterone decanoate would be more than one month. At day 30 after injection, 250mg or more of this drug would still be present in the body.
Last edited by MickeyKnox; 02-25-2013 at 03:22 PM.
Knowledgeable Member
Can`t ask for a much more detailed answer than that.
Productive Member
Nicely said Mickey. Lets await a rebuttal from Bonaparte. Lol.
Banned
...and Atomini and TurkishJuicer. Along with Bonaparte, I know these two have a solid education in this particular background.Originally Posted by warmouth
Banned
Nice, Mickey. I think you're pretty much dead on. The test suspension would be the only questionable one. But being half life, you probably got that right too.
Good post!
Banned
I agree Pete. I changed it to "Less than 1 day" as im not certain to the hours on this one.
Banned
Yeah, it being water based and injected up to 3 times daily, was what made me think of it.
Good job though, nonetheless!
Banned
T3 needs to be corrected to 2.5 days. This one is very important, as someone who doesn't dose T3 properly could end up with the fatal condition of Thyroid Storm.
Propionate needs to be corrected to 4.5 days.
All others look good after quickly skimming the list.
The other thing to remember is that half-lives are never set in stone. They depend on many different factors, and individual metabolism is a huge one. This is why when I tell people about half lives, I always say "APPROXIMATELY x days" or "APPROXIMATELY x - y hours". Never ever tell people half-lives are set-in-stone numbers, they vary depending on many different factors.
Banned
I totally agree with this. Its never exactly the same with everyone. In fact, i will include this Atomini.
Thanks for the input.
Junior Member
Awesome information guys.
Knowledgeable Member
One addition...aromasin (exemestane), half life 8.9 hrs.
http://www.ncbi.nlm.nih.gov/pubmed/14671195
HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~
How is nand deca 14 days and the deca ester 15? (not that it matters) could be a typo.
Banned
Thanks for the reminder!
Im actually currently putting together an article on the differences and misconceptions of Aromasin and Adex and should have caught that..doh!
Knowledgeable Member
Now we're talking. This direct compare/contrast between these two compounds has been a long time coming!
AR-Hall of Famer
Those half lives are, for the most part, double the plasma half-lives published in studies. Enanthate is around 6 plus or minus 1 day (so 5-7 days). But each study will list something a bit different.
And there are two types of measurable half life: plasma and elimination.
Banned
Thanks Bonaparte, Austin.
Keep them coming - that's what we want. A final article that can be used and relied on for the future.
Associate Member
This is one of the best threads in awhile
Mickey your amazing !!! Keep up the good work
Banned
That is what the anabolic steroid using community has required for a good long while now. I have seen so many different listed half-lives over the years, its baffling. If you can get a nice list up of all the half-lives, and cite references to valid clinical data, it should be the go-to half-life list for everyone everywhere. Too many numbers being thrown around off the top of people's heads at this point in time (hence my clarification about T3's half life, and i've seen people say that T3's half life is 4 hours, 8 hours, 24 hours, and 2 days). It's ridiculous. At the end of the day, as I mentioned, none of these numbers are set in absolute stone due to individual metabolism, but they are good reference numbers to go by, but lets make sure they are verified numbers.
Banned
Exactamundo!
If we all chip in and give our .02, in the end we'll have a solid list of half lives/esters that can be used as a template to refer to for all AAS cycles. I dont know them all, not many do. So please comment on anything you see that may be incorrect.
At the end, I'll post up a thread with this updated article.
Knowledgeable Member
Knowing the half-life of a hormone is useful but I think you have to be careful when basing your plan on the half-life of a particular compound. For example, Test-e or Cyp, both carry half-lives that stretch into the 1wk range, but this doesn't take into account the blood spike. With either compound, testosterone levels spike at approximately 48hrs post injection and then sharply fall back to baseline. This is a massive problem with a lot of TRT plans you seen calling for one injection every 7-14 days. There's no stability in levels with this kind of protocol. Anyway, just something to think about.
Banned
Remember that you probably won't be able to find exact numbers of all half-lives of certain compounds. You might find one study that claims X drug's half life is 8 hours, and another study finding it to be 12 hours. This is when you'll just have to say "X drug has a half life of approximately 8 - 12 hours". Be prepared for the possibility of not finding any data at all for certain things as well.
Knowledgeable Member
Very true. Seen many claims that Test-cyp carries a half-life of 12 days and other say 8. You can find the same discrepancy with most hormones.
Banned
Yes, this is why I never take half-lives as precise and exact numbers. The human body doesn't understand how many days or hours a drug has been in its system. All it knows is what it needs to do in order to metabolize X, Y, or Z drug through its systems. Some people's bodies do it quicker than others, and some slower than others. This is why we can only give general guidelines as to half-lives, and especially concerning what you mentioned about peaking blood plasma levels. This is why I find it hilariously flawed when people say "long estered anabolic steroids such as Testosterone Enanthate take longer to work in the body" LOL LOL LOL LOL. Uh, no... any drug you put in your system starts working IMMEDIATELY, and the fact of the matter is, as you mentioned in a previous post, Testosterone Enanthate levels spike within 48 hours following administration.
Banned
May start working immediately, but i think people are more attracted to prop(or short esters) because of the faster results. Or am i totally off base here? I know for a fact if i use 150mgs prop EOD i see results in 2 weeks. If i use 500-750mgs E it's about 2 weeks longer. But you're just saying that your body knows it's getting synthetic from the start?
Banned for repping Dangerous Substances
Great stuff guys. Very informative thread and your article Micky is a good reference guide. Thx...crazy
Knowledgeable Member
All that matters is how fast the ester detaches from the hormone. Once the ester is detached (using testosterone as an example) you have the same testosterone hormone in the body regardless of the prior ester attached. If you're using a compound like Testosterone Enanthate and and blood levels spike within the first 48hrs, this means the hormone has become active in the body much faster than many tend to believe.
On the issue of test-p results, keep in mind (using your example) if you inject 150mg/eod this gives you a weekly average of 525mg/wk and based on the actual amount of testosterone in this compound (appx. 84mg per 100mg) this gives you an average of 441mg of active testosterone per week. Now consider Test-cyp, the actual amount of testosterone in this compound (appx. 70mg per 100mg) this gives you an average of 350mg of active testosterone per week. Pretty notable difference.
For those that don't understand this, when you consider any steroid, the total composition of the compound is part hormone and part ester. The larger the ester the more mass it takes up in the compound, therefore the lower the amount of active hormone on a per milligram basis.
All that said, while there's a sharp spike with larger ester versions, the spike is sharper with smaller versions and that's why some notice slightly faster differences. However, while you often hear it takes a long time for say Test-e to kick in, I think many might be surprised how much faster the total action and results are if they were using a high quality human grade brand...verifiably human grade, not one that's assumed to be. Also consider TRT patients, a lot of TRT patients feel noticeably better within the first couple of weeks, and in the U.S. they're most commonly using Testosterone Cypionate.
Banned
You're numbers are correct and nice post. Would you agree that your typical TRT patient and 90% of the members on this board have totally different goals? Maybe i'm off on the 90% part, but you get what i'm saying.
Knowledgeable Member
Absolutely, the goals are definitely different by far but the action of the hormone, no matter why you're using, it is still the same. Think about Trenbolone, for 30yrs it was enormously successful in human medicine, primarily in Europe and I don't think any of those patients were trying to get ripped out of their mind or put on gallons of muscle. But it was still the same hormone we use today, functions the same way and was beneficial for the same reasons in a functionality sense.
As far as your direct example, while the goals in a grander sense are different for the TRT patient vs. the gym rat or recreational user, there are still some strong similarities. Think about it...many TRT patients have lost a lot of strength and muscle mass, and that's one of the big reasons they find themselves on a TRT plan. Many have an extremely difficult time with body fat when levels are low, it becomes difficult to lose, more difficult than it should be and when they do lose it (while muscle mass loss always occurs when losing weight) they lose more than they should. If you think about it, the goals of a TRT patient and a gym rat, while they are definitely different they do share some strong similarities.
Banned
Yes, i agree. The similarities are almost identical. And that's cool. I was simply stating that different AAS will have more, or maybe faster, results than others. Nonetheless, you brought up great points which only(in my belief) enhanced the thread a bit.
Banned
Yeah metalject pretty much just answered everything and said everything I would've told you. Great info.
MONITOR
Great thread mickey very good info.
New Member
Thanks good explanation I find that your site really goes into detail so even a novice like me can understand
Senior Member
Well said man! What about mast?
Banned
Imho, plans (TRT, AAS cycles) are based upon goals, associated esters, and frequency of pinning, not serum spikes. These spikes are irrelevant in planning as the serum spikes will happen regardless. The only difference is the timing of the spike. As you already indicated the shorter the ester, the faster the spike, and vice versa.
The "massive" problem with TRT is not, imho, the serum spikes. Its, rather, the half life that is the most misunderstood area of testosterone. Many TRT docs are not educated in this field and therefore administer incorrect protocols that create uneven serum levels which ultimately leads to a roller coaster effect. The timing of the injections do not reflect stable protocols.
Here's a list of the more common ester weights for future reference for anyone to refer to..
Esters - Actual mg/100mg dose
Test Susp 100
Tren Acetate 87
Test Prop 83
Test Enth 72
Test Cyp 70
Test Undecan 63
Nand Phenyl 67
Nand Deca 64
The shorter (lighter) the ester, the quicker your body can cleave it off. The quicker your body can cleave off the ester, the faster you will see results. This is precisely why you and i and anyone else will see results sooner than long estered testosterone like enth, cyp..ect.
They do. Youre correct Pete.
On it right now. Thanks Chive.
Senior Member
You're a beast Mickey! Link master it is
Anabolic Member
Yeah, i was thinking suspension half life was something like 8 hours, but now not sure....
Knowledgeable Member
I think the serum spike, if we're being as accurate as we can be is the most important aspect. By gauging the spike you can more accurately gauge when you need to pin, which will create a more fluid plan/schedule rather than basing it on half-lives. And this is exactly what the problem is with so many TRT plans, physicians base pinning on the half-life, do not take into account the spike, which results in far too infrequent injections and roller coaster levels.
Maybe I'm not fully understanding what you're trying to say but this is how I see it.
Banned
After some rather extensive research i just finished, half life is between 6-8 hours.
Knowledgeable Member
Really? Are we talking about Testosterone Suspension? I've always thought it was a good bit longer than that. Curious as to where you found this info.
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