Prami question

[allskill87]

What exactly does it do, is it a must for a cycle with tren? Thanks

[austinite]

Prolactin control.

[allskill87]

Prolactin control.

So basically helps w gyno? Also would you take just during the cycle while ur on tren and at what dosage? I'll be running adex .25 eod thru the while cycle so just not sure if I need to add this during the whole cycle or just once I start the tren up

[austinite]

So basically helps w gyno? Also would you take just during the cycle while ur on tren and at what dosage? I'll be running adex .25 eod thru the while cycle so just not sure if I need to add this during the whole cycle or just once I start the tren up

It all starts with Estrogen control. AI on cycle is where you start. Most folks develop the need for prami because an AI wasn't used, or wasn't used properly. Prami is not exactly a smooth compound. It could be quite harsh for some. This is why people keep it on hand rather than using it.

Bloodwork tells all. Keep your estrogen level under control.

[allskill87]

It all starts with Estrogen control. AI on cycle is where you start. Most folks develop the need for prami because an AI wasn't used, or wasn't used properly. Prami is not exactly a smooth compound. It could be quite harsh for some. This is why people keep it on hand rather than using it.

Bloodwork tells all. Keep your estrogen level under control.

Alright cool, I'v never really had any problems while using adex. I guess I can pick it up and hold on to it and if anything happens while on I'll start using it, what would be the appropriate dosage?

[redz]

There are other options too like caber and bromo that do the same thing.

[allskill87]

There are other options too like caber and bromo that do the same thing.

Yeah I can't get either from my source and I trust arr's products

[MickeyKnox]

It all starts with Estrogen control. AI on cycle is where you start. Most folks develop the need for prami because an AI wasn't used, or wasn't used properly. Prami is not exactly a smooth compound. It could be quite harsh for some. This is why people keep it on hand rather than using it.

Bloodwork tells all. Keep your estrogen level under control.

I agree with Austin, of course.

I always thought this was a pretty accurate write up on Prami. Its from Lion at AR-R.

"Pramipexole – The Best Dopamine Agonist

Dopamine Agonist? I thought Prami controlled prolactin in research subjects? That’s right it does, however it does so by acting as a dopamine agonist. Dopamine and Prolactin have an inversely proportional relationship. Meaning if Dopamine is high – Prolactin will be low. Use of a Dopamine agonist has proven the preferred method in several studies and in practical research applications to lower Prolactin levels. So what makes Prami the BEST?

Well first let’s look at Prolactin and what its effects are in research subjects. Prolactin is a hormone released by the pituitary gland. It induces lactation and combined with excess estrogen will encourage breast tissue growth (gyno in male research subjects). It is also responsible for the refractory period, the time which it takes a make to fully recover after sexual activity to be able to perform the act again. Obviously it plays a key role in sexual function, or dysfunction.

The main reason for use of a dopamine agonist in research subjects is 2 fold. 1- To avoid any breast issues in male research subjects and to avoid sexual dysfunction. The agonist activity on dopamine receptors lowers prolactin levels sufficiently to help with these effects. So what makes Prami the best? Well dopamine agonists act on the d2 and d3 receptors both. Prami, however, in addition to exerting potent effect on d2 receptors has a 7 times higher affinity for the d3 receptor than any other dopamine agonist. Well the d3 receptor is responsible for males’ sexual interest, sexual arousal, and sexual function. Prami will not only lower overall prolactin levels in research subjects, it will agonize the very receptor responsible for playing a key role in male sexual function. It does this 7x more than any other dopamine agonist. Prami crushes sexual dysfunction.

Other benefits of Prami include a neuroprotective effect. Offsetting effects of neurodegenerative diseases (ie Parkinson’s , Alzheimer’s).It has been shown to elevate mood and stave off depression in research subjects.

Where as bromocriptine and cabergoline have been associated in studies with increased cardiac incidents – this is not the case with Pramipexole. In fact in the very same study it was found that with Pramipexole, “ no such increases were observed for nonergot-derived drugs-Pramipexole.”

Prami also induces a 2 hr increase im GH release im research subjects. A GH increase statistically significant enough to be repeatedly noted and mentioned in several studies as a demonstrated effect.

When administered to research subjects properly, slowly increasing amount administered till desired dose is reached. Prami is an extremely well tolerated research compound which will illicit all the benefits mentioned above. It truly is the best Dopamine Agonist for our research purposes."

[allskill87]

I agree with Austin, of course.

I always thought this was a pretty accurate write up on Prami. Its from Lion at AR-R.

"Pramipexole - The Best Dopamine Agonist

Dopamine Agonist? I thought Prami controlled prolactin in research subjects? That's right it does, however it does so by acting as a dopamine agonist. Dopamine and Prolactin have an inversely proportional relationship. Meaning if Dopamine is high - Prolactin will be low. Use of a Dopamine agonist has proven the preferred method in several studies and in practical research applications to lower Prolactin levels. So what makes Prami the BEST?

Well first let's look at Prolactin and what its effects are in research subjects. Prolactin is a hormone released by the pituitary gland. It induces lactation and combined with excess estrogen will encourage breast tissue growth (gyno in male research subjects). It is also responsible for the refractory period, the time which it takes a make to fully recover after sexual activity to be able to perform the act again. Obviously it plays a key role in sexual function, or dysfunction.

The main reason for use of a dopamine agonist in research subjects is 2 fold. 1- To avoid any breast issues in male research subjects and to avoid sexual dysfunction. The agonist activity on dopamine receptors lowers prolactin levels sufficiently to help with these effects. So what makes Prami the best? Well dopamine agonists act on the d2 and d3 receptors both. Prami, however, in addition to exerting potent effect on d2 receptors has a 7 times higher affinity for the d3 receptor than any other dopamine agonist. Well the d3 receptor is responsible for males' sexual interest, sexual arousal, and sexual function. Prami will not only lower overall prolactin levels in research subjects, it will agonize the very receptor responsible for playing a key role in male sexual function. It does this 7x more than any other dopamine agonist. Prami crushes sexual dysfunction.

Other benefits of Prami include a neuroprotective effect. Offsetting effects of neurodegenerative diseases (ie Parkinson's , Alzheimer's).It has been shown to elevate mood and stave off depression in research subjects.

Where as bromocriptine and cabergoline have been associated in studies with increased cardiac incidents - this is not the case with Pramipexole. In fact in the very same study it was found that with Pramipexole, " no such increases were observed for nonergot-derived drugs-Pramipexole."

Prami also induces a 2 hr increase im GH release im research subjects. A GH increase statistically significant enough to be repeatedly noted and mentioned in several studies as a demonstrated effect.

When administered to research subjects properly, slowly increasing amount administered till desired dose is reached. Prami is an extremely well tolerated research compound which will illicit all the benefits mentioned above. It truly is the best Dopamine Agonist for our research purposes."

So you think I should just get it and keep it on hand? If gyno ( and from reading that any sexual prods) occur start prami up? At Whst dosage would you recommend?

[austinite]

^ no. If Gyno occurs Prami will do nothing to reverse it a lump. You will need Ralox or Tamox for that.

[allskill87]

^ no. If Gyno occurs Prami will do nothing to reverse it a lump. You will need Ralox or Tamox for that.

Ok sohow would I know if i needed to add the prami during the cycle

[austinite]

Ok sohow would I know if i needed to add the prami during the cycle

Again, blood work will show if you have elevated blood prolactin levels. But you can be concerned with lactating, erectile dysfunction, no libido, vision problems etc...

Manage your estrogen properly. Get a sensitive E2 assay. It's crucial.

[allskill87]

Again, blood work will show if you have elevated blood prolactin levels. But you can be concerned with lactating, erectile dysfunction, no libido, vision problems etc...

Manage your estrogen properly. Get a sensitive E2 assay. It's crucial.

Ah ok got ya, I'v never had any of those problems yet. I had blood work done last week n doc said everything was good