When using Nolvadex for PCT I understand that it stimulates the production of natural testosterone. Im curious as to why this increase in T does not cause suppression of HPTA as when injecting while on cycle??
When using Nolvadex for PCT I understand that it stimulates the production of natural testosterone. Im curious as to why this increase in T does not cause suppression of HPTA as when injecting while on cycle??
You have much to learn grasshopper!
Nolvadex (among others) is used to attempt to re-start the HPTA (ie your natural testosterone production) after its suppression from cycling with exogenous testosterone.
This is a really good place to start
http://forums.steroid.com/anabolic-s...-database.html
4charTamoxifen citrate also possesses the ability to increase production of FSH (follicle stimulating hormone) and LH (luteinizing hormone). This is accomplished by blocking negative feedback inhibition caused by estrogen at the hypothalamus, which (via the actions of GnRH) fosters the release of the mentioned pituitary hormones. This is very similar to the function of Clomid® and cyclofenil. Since a higher release of LH can stimulate the Leydig’s cells in the testes (men) to produce more testosterone, tamoxifen citrate can have a positive impact on one’s serum testosterone level. This “testosterone stimulating” effect is an added benefit when preparing to conclude a steroid cycle. Since anabolic/androgenic steroids tend to suppress endogenous testosterone production, tamoxifen citrate can help restore a balance in hormone levels. It is most commonly used as part of a comprehensive post cycle recovery program.
Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
Thanks for the input. I understand how the action Nolvadex works. The question I have is we know exogenous testosterone suppress the HPTA but the T your body produces as a result of Nolvadex does not. Is this because the amount of T produced via action of Nolvadex is a much smaller amount??
Nolvadex is an ER antagonist in the brain which means it binds to the estrogen receptor but doesn't activate it. By doing so it makes the brain believe there is less estrogen in circulation than there actually is which prompts the brain to signal GNrH production which eventually stimulates testosterone production. It works by inhibiting the negative feedback loop of the HPTA.
This thread in particular helped me to grasp what is going on.
http://forums.steroid.com/anabolic-s...ffect-you.html
I'm on a cycle of test prop and tren, what would y'all recommend for a pct?
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