3x a week injections

[Machdiesel]

Wondering if anyone here injects 3x a week and has BW to confirm it lowered e2? Thinking about switching from 2 to 3x to keep e2 down

[Times Roman]

not familiar with the correlation between injection frequency and E2 levels?

Maybe I'll learn something today?

[Times Roman]

(but if I had to guess, I'd guess there is a low/no correlation on long burning esthers)

[kelkel]

Less injected at one time = less spike in E2.

Op, I'm pretty sure 2Sox goes eod SQ.

[Times Roman]

Less injected at one time = less spike in E2.
Op, I'm pretty sure 2Sox goes eod SQ.

ok, I understand that. but everything else being the same, does more frequent injections mean that the overall average of E2 is reduced.

Spikes are usually followed by troughs, with the overall average being the same.

[Beethoven]

Kel you are right, 2sox injects eod. I know he still has a bit of E2 control but it is lower eod and if memory serves he has a very good test level. That will be my next change.

[Machdiesel]

To clarify instead of injecting 70mg twice a week, I'd be injecting 45mg three times a week. My highs will be lower thus theoretically keeping e2 lower. I say theoretically because at some point you get diminishing returns. Going from once a week injections to twice a week should reduce e2, but would going from two to three really help?

[kelkel]

ok, I understand that. but everything else being the same, does more frequent injections mean that the overall average of E2 is reduced.

Spikes are usually followed by troughs, with the overall average being the same.

Yes. It's simply less to turn over to E2. Most of the top doc's will recommend this as a first step in avoiding an AI. Many clinics, including LowT will do this as well.

To clarify instead of injecting 70mg twice a week, I'd be injecting 45mg three times a week. My highs will be lower thus theoretically keeping e2 lower. I say theoretically because at some point you get diminishing returns. Going from once a week injections to twice a week should reduce e2, but would going from two to three really help?

Only BW will tell. Try if for a month and pull some BW. We'd all be interested in how you make out. No fasting required for E2. And if your doc will do it, ask to pull a Sensitive E2 Assay, which is the proper test, along with a standard Estradiol test. Seeing the difference between the right test and wrong test is always interesting.

[BigPimpin76]

Interesting...

Sent from my iPhone using Forum

[kcwebguy]

I have been wondering about this also. Was thinking about it because I have a couple of sources and this allows me to not have to mix or do multiple pins on a given day.

[2Sox]

Less injected at one time = less spike in E2.

Op, I'm pretty sure 2Sox goes eod SQ.

Correct, I inject EOD - 30mg which averages to 105mg/week. It keeps my E2 lower in general but not low enough for my comfort/liking. Just changed my aromasin dosing to 12.5mg E4D (the day of my hcG shots) and I'll see how that goes.

I have a strong feeling that the largest cause of my E2 discomfort comes from my hCG shots (250iu 2x week). I feel extremely fatigued within an hour of the injection UNLESS I take an AI. I'm considering doing daily 100iu - which I'd have no problem with. What do you think?

[Black]

I have been injecting test EOD from almost 2 years now. I inject 40mg (averages out to 140mg a week) EOD with a 29-30g 1/2" insulin pin. I started this protocol under the theory that the less you inject, the less there is to aromatize. Also, I started to noticed some Androgel users not having any estrogen issues and they weren't taking an AI (small, daily doses).

By dosing this way, I keep my total test around 900 and my estrogen around 20. I even went as far as ED injections of 20mg. However, I am fairly lean (usually) and this low of a dose had my estrogen at 10 (sensitive assay). A little lower than I would like, however, I felt fine. I moved to EOD injections for the simple reason of injecting fewer times.

*Note - I started this protocol because I was crashing my estrogen with Arimidex, even at low doses. I just couldn't get my estrogen at a consistent, comfortable level.

Correct, I inject EOD - 30mg which averages to 105mg/week. It keeps my E2 lower in general but not low enough for my comfort/liking. Just changed my aromasin dosing to 12.5mg E4D (the day of my hcG shots) and I'll see how that goes.

I have a strong feeling that the largest cause of my E2 discomfort comes from my hCG shots (250iu 2x week). I feel extremely fatigued within an hour of the injection UNLESS I take an AI. I'm considering doing daily 100iu - which I'd have no problem with. What do you think?

2sox, just saw your post after I completed mine. I take my HCG along with my test at EOD injections. I dose it at 125iu. Definitely something I would try, especially if you are injecting EOD already. Just curious, how is your bodyfat?

[2Sox]

^^^^Referring to your post above:

125iu hCG, EOD with my T injections seems to be a very good idea especially because of what I suspect about my E2 reaction to my dosing of hCG now.

Regarding body fat: I don't know my body fat % but I'm fairly lean. Been a long distance runner forever. (Although now it's more of a long distance walker/jogger).

[kelkel]

Correct, I inject EOD - 30mg which averages to 105mg/week. It keeps my E2 lower in general but not low enough for my comfort/liking. Just changed my aromasin dosing to 12.5mg E4D (the day of my hcG shots) and I'll see how that goes.

I have a strong feeling that the largest cause of my E2 discomfort comes from my hCG shots (250iu 2x week). I feel extremely fatigued within an hour of the injection UNLESS I take an AI. I'm considering doing daily 100iu - which I'd have no problem with. What do you think?

Crisler is a proponent of daily dosing. Can't hurt to try.

[2Sox]

Crisler is a proponent of daily dosing. Can't hurt to try.

Hmm.... More food for thought.