This is curious. Been on my protocol for about a year, everything has been good. All of a sudden I'm getting what is similar to Bacne. So there were only two changes made: started taking Cialis 5 mg daily and my test brand changed. Came off the Cialis and still there. I'm going to schedule some BW since its been a while since I've checked test and E. Could one brand be stronger than another and be causing a spike in E2? I haven't had any other symptoms, just curious if any of you have experienced this.