1 year blood work and adjustment,ai needed ?

[tripperdogg]

i am currently taking .50 ml of test cyp.[200mg/1ml]on wedsnesday and sunday. i also take hcg 3 times a week ,250iu's. recently had my test serum checked,950 on a 348-1197ng/dl scale, estradiol checked ,37.2 on a 7.6-42.6 pg/ml scale and estradiol,sensitive checked ,22 on a 3-70 pg/ml.my doctor says he wants to start me on an ai now , 3 times a week to bring the estradiol number down. this is what i'm questioning. my e2 number looks great and the estradiol number doesnt seem too high. taking an ai 3 times a week should crush my e2 in about a month. they want to do another blood test in 6 weeks. what do you guys think ? should i only take the ai once a week. i havent picked up the perscription yet, but i think she said 1 mg 3 times a week. sounds high doesnt it ? thank you for your time

[kelkel]

Did you switch docs Tripper? If your E2 sensitive is 22 you're in great shape and do not need an AI whatsoever. Most of the top guys in the industry like Crisler, Vergel, LEF Foundation, etc., recommend between 20 - 30 on a sensitive assay. Also know that standard estradiol is geared toward women and tends to read higher for men, thus resulting in the unnecessary use of aromatase inhibitors. Again, the top docs will tell you this. Google LEF and Estrogen and you'll find some good articles. 1 mg x 3 per week would crash your E2 in no time. Educate her.

[tripperdogg]

This is the same doc. You know him. He told his nurse to start me on an ai based on my estradiol number. Not my e2. I said don't you mean my e2 and she said no. I haven't taken anything yet but I thought that this recommendation sounded fishy.the old nurse has left the practice and this is his new one. . I was right to question this recommendation wasn't i?

[OingoBoingo]

Most of the top guys in the industry like Crisler, Vergel, LEF Foundation, etc., recommend between 20 - 30 on a sensitive assay.

kelkel,

Although LEF does indeed recommend E2 be kept between 20 and 30, unless I missed something, LEF does not recommend the sensitive assay (except in special cases).

[kelkel]

kelkel,

Although LEF does indeed recommend E2 be kept between 20 and 30, unless I missed something, LEF does not recommend the sensitive assay (except in special cases).

Correct. But they are changing. Crisler's been beating them down about it. It's been a money thing as standard estradiol costs about $20 bucks I believe and the Sensitive Assay is a little over $200. Ridiculous difference. Always about money, even with the associations allegedly out there to help.

[kelkel]

This is the same doc. You know him. He told his nurse to start me on an ai based on my estradiol number. Not my e2. I said don't you mean my e2 and she said no. I haven't taken anything yet but I thought that this recommendation sounded fishy.the old nurse has left the practice and this is his new one. . I was right to question this recommendation wasn't i?

I sincerely believe you are correct. How do you feel?

[Beethoven]

I sincerely believe you are correct. How do you feel?

That's right. Even though the hCG raises mine and I take an AI, I've missed the AI and felt no difference.

[kelkel]

That's right. Even though the hCG raises mine and I take an AI, I've missed the AI and felt no difference.

I've tested at 200 on a Sensitive Assay 3-70 scale and felt no difference.

[tripperdogg]

I have felt alittle bloated , not bad but noticeable in face,sensitive nipples, possible dry skin from cold winter here. Other than that feel pretty good, 51 years old is interesting when it comes to forgetting things.Well, what do you think,.25 mg twice a week or do nothing at all. Doc is going to retest in 6 weeks.

[bullshark99]

Tripper,

Personally I would give it a shot. Yes, I would do .25 each day (twice) 24 hrs post your injection. Would be very surprised if this crushed your E2, but also would be surprised if you feel much if any different? Your numbers look pretty good, maybe just a tad high. if you are feeling a litle bloated, maybe this is the ticket.
I do .5 per week on 200mgs, my last test 2 weeks ago had me at 13, so im gonna try .25 once a week. Only difference between our protocols is i only inject one time per week, also 500 ius of HcG not 750 (two pins).
My TT was 784 on day 6, my free was 27.99 (5-21) a tad bit over and my % Free was 3.57 (1.5-4.2) Overall I think this is about as "dialed in" as I have ever been.

[BallSak]

I have felt alittle bloated , not bad but noticeable in face,sensitive nipples, possible dry skin from cold winter here. Other than that feel pretty good, 51 years old is interesting when it comes to forgetting things.Well, what do you think,.25 mg twice a week or do nothing at all. Doc is going to retest in 6 weeks.

Your E2 numbers look perfect to me. I wouldn't wanna mess that up. Even .25mg of anastrozole could screw things up.

[kelkel]

Tripper,

Personally I would give it a shot. Yes, I would do .25 each day (twice) 24 hrs post your injection. Would be very surprised if this crushed your E2, but also would be surprised if you feel much if any different? Your numbers look pretty good, maybe just a tad high. if you are feeling a litle bloated, maybe this is the ticket.
I do .5 per week on 200mgs, my last test 2 weeks ago had me at 13, so im gonna try .25 once a week. Only difference between our protocols is i only inject one time per week, also 500 ius of HcG not 750 (two pins).
My TT was 784 on day 6, my free was 27.99 (5-21) a tad bit over and my % Free was 3.57 (1.5-4.2) Overall I think this is about as "dialed in" as I have ever been.

Bloating could simply be diet related.
Nipple sensitivity is not abnormal. Everyone seems to expect absolutely no feelings in them. Not true. Sensitivity doesn't automatically equal issues.

Lets do some math. On a 500 mg test cycle the avg Adex dose is .25 eod. This equates to .875 per week (.25 x 3.5) and on such a cycle your Test can be upwards of 3-4K ng/dl. Now, in Trippers position doing .5 total for the week with what appears to be a great sensitive assay outcome could not possibly do him any favors, imho.

Interesting stuff though. We all respond so differently and those responses change over time.

Edit to say that I know this doctor personally and I don't like to second guess him. Tripper I'm wondering if you expressed your feeling of bloat and nip tenderness which could lead him to surmise a little lower E2 is better?

[tripperdogg]

During my January appointment when reviewing my blood work over the year and seeing that my test numbers tanked when I was trying to lower my hemoglobin/hematocrit numbers,he said we may need to add an ai since I had to increase my dosage significantly to get my numbers back up[they were in the 288 range-lab corp scale]. So I guess he liked the new test numbers and decided to add ai from his previous notes and bw. I will have bw in 6 weeks, I guess I will not take the ai at all and see if I keep the same e2 numbers . What do you think or should I try ,.25mg ,once a week ?

[kelkel]

22 on a sensitive assay is just fine, imho. But I'd still fill the script. Always good to stock up. That said, the relationship with your doc is important so try to find a balance.

[tripperdogg]

so just wait using my current protocol and get bw in 6 weeks. inspect results at that time to either add ai at or keep on with the current protocol. thanks guys. I'm not rocking the boat with the doc, just looking out for my health. All is good

[kelkel]

I actually feel better around 30 or so on the sensitive assay. We are all different.

[lovbyts]

22 on a sensitive assay is just fine, imho. But I'd still fill the script. Always good to stock up. That said, the relationship with your doc is important so try to find a balance.

Ha, exactly what I was going to say, you should see my stash from over the years. lol

It sounds like your doc may be tweaking things just to experiment a little. It probably could be due to a mix of his notes from the past and something you said as mentioned. I dont think there is anything wrong with questioning him next time you see him and I always go with the old school, how do you feel? If you feel good like said and your numbers are OK then I would not change anything unless you have to.

[tripperdogg]

thanks guys ! got the scripts in the mail today,just test serum and estradiol testing in 1 month. guess we'll see what we see in that time. i dont know why he doesnt want to see e2, but maybe because its a more expensive test like kel said. thanks again

[tripperdogg]

one last thought, picked up the percription at the pharmacy and directions said 1 mg 3 times a week. sounds like way too much. Should I call my doc and ask to have them test e2 again also. thanks

[Chauffeur]

thanks guys ! got the scripts in the mail today,just test serum and estradiol testing in 1 month. guess we'll see what we see in that time. i dont know why he doesnt want to see e2, but maybe because its a more expensive test like kel said. thanks again

Estradiol = E2. The terms are used interchangeably.

The difference in the tests you had done is that one is the standard assay, the other is the sensitive assay. The latter is the more accurate of the 2.

If I were you I wouldn't change anything at all. Your sensitive estradiol of 22 is perfect for most guys. Many guys work really hard to get their estradiol to 22 on the sensitive assay.

Obviously, it's all about how you feel, but it appears that you're dialed in better than most.

Adding even a small dose of an AI will drop you below what many consider to be the ideal range for estradiol (20-30).

[OingoBoingo]

one last thought, picked up the percription at the pharmacy and directions said 1 mg 3 times a week. sounds like way too much. Should I call my doc and ask to have them test e2 again also. thanks

What is your prescription?

[tripperdogg]

doc wants to start anastrazole at 1 mg 3xs a week. I know way too much !

[Chauffeur]

doc wants to start anastrazole at 1 mg 3xs a week. I know way too much !

That is INSANE. Definitely do not do this.

[Beethoven]

That is INSANE. Definitely do not do this.

^^^ Fill the script but do not take that dose. Keep doing what you have been and save the extra for a blasty day.

[tripperdogg]

will do , thanks guys