Arimidex dosage

[ssj4goku1992]

Hi guys,

Sorry for making a new thread but I am getting desperate seeing that nobody is answering or replying to my thread...
I would like to know the dosage of arimidex for lowering estrogen in a non TRT using person (me). Can you please help me with the dosage? Because that is the only thing that I need right now.

Testosterone: 720 ng/dl
Estrogen: 44 picograms/ml (at top of the range)
Age: 22 years old
I have gyno (without ever using steroids, it developed in the last year or so) so I will also use 40 mg Nolvadex daily for a week then 20 mg for the rest until my gyno disappears. Any help please?

PS: How do you split a tablet in very small pieces? (like a 1 mg tab in a 0.25 mg dose)

[OingoBoingo]

Anastrozole is strong and very effective. If you are not careful, you can crash your E2 so fast that you won't believe it.

I don't remember much about your thread, but you should find out why things are screwed instead of just taking Anastrozole.

Did you measure your Vitamin D?

There really is no recommended dose for you, but I would start low and go slow. Take 0.25mg once per week and see how you feel. The day before you take it the second and third times, you may want to test your E2 to see where you're at.

Currently I take 0.25mg every 12 to 14 days; I can feel when my E2 rises above 32 or so, and take Anastrozole when I need it.

The easiest way to cut the pills is with a pill cutter. Any good pharmacy should have one. Just cut the 1mg pill in half, and cut those in half again. Don't worry about being exact; a little bit off won't cause problems.

The hard way to cut the pill is with a razor.

[kelkel]

And remember, if that's a standard estradiol test it reads higher and less accurate that a Sensitive Estrogen Assay which is what should be pulled for accuracy.

[ssj4goku1992]

The simple fact that I got gyno in the last year without using steroids or so is basic proof that my E2 levels are off the limits, even if it is a standard estradiol test or a sensitive one. I have no idea about the cause... Sadly my stupid doctors have no idea too...
Doesn't a dosage of once every two weeks create spikes in your E2 levels? Isn't a EOD dosage far better for maintaining a balanced hormonal level? And if so how do I split a 1 mg tab in 0.125 mg or so (what I would need for a 0.5 mg dosage per week). You are suggesting an even lower dose per week, a 0.25 mg, so it's even more important.

I would like to heal the cause but I have no idea how... Can a vitamin D deficiency increase your E2 to these levels? I don't think so...

PS: I was specifically told by the Admin of another forum to not use the Sensitive Estrogen test because it will give you a lower number than what you actually are...

[jjalison]

Dosage is more individual. That being said I would recommend you start low, like .25 EOD and work up from there if needed. Also don't take it until you experience sides.

[2Sox]

The simple fact that I got gyno in the last year without using steroids or so is basic proof that my E2 levels are off the limits, even if it is a standard estradiol test or a sensitive one. I have no idea about the cause... Sadly my stupid doctors have no idea too...
Doesn't a dosage of once every two weeks create spikes in your E2 levels? Isn't a EOD dosage far better for maintaining a balanced hormonal level? And if so how do I split a 1 mg tab in 0.125 mg or so (what I would need for a 0.5 mg dosage per week). You are suggesting an even lower dose per week, a 0.25 mg, so it's even more important.

I would like to heal the cause but I have no idea how... Can a vitamin D deficiency increase your E2 to these levels? I don't think so...

PS: I was specifically told by the Admin of another forum to not use the Sensitive Estrogen test because it will give you a lower number than what you actually are...

You're doing the smart thing by asking questions and doing your own research. But I'm sure you know that it's crucial you find the cause of you higher E2 - and that you find a doctor you can work with on this. By the way, do you have any theories as to what is the cause of this?

In the final analysis, only you can decide what's best for you. The sensitive assay is best for men and there are reasons for this and you ought to find out why. Anastrozole is not the only E2 control medication by far. I'm a big fan of Exemestane. I take 1/2 pill a week. Does the trick. You might want to look into it.

[OingoBoingo]

Doesn't a dosage of once every two weeks create spikes in your E2 levels?

I don't measure my E2 daily, and what's important is to keep E2 between 20 and 30 as measured by the E2 standard assay. What I know is that if I take 0.25mg Anastrozole when I start to experience high E2 symptoms, the symptoms will go away in 6 to 11 hours depending on what's in my stomach. And then it takes 12 to 14 days for the symptoms to come back.

If you are talking about E2 rebound, that is indeed a concern for guys with Testosterone at supraphysiological levels (guys on a cycle), but not for guys on Testosterone at physiological levels (guys on TRT). It's one of those myths often repeated by the Aromasin fanboys. Gotta remember that your body is always working to get rid of E2, and with Testosterone at supraphysiological levels the mechanism is overwhelmed.

I should also say that I take 75mg Zinc spread throughout each day.

Isn't a EOD dosage far better for maintaining a balanced hormonal level? And if so how do I split a 1 mg tab in 0.125 mg or so (what I would need for a 0.5 mg dosage per week). You are suggesting an even lower dose per week, a 0.25 mg, so it's even more important.

Your plan of pegging E2 at 22 just can't be done. You will be doing great if you can keep E2 between 20 and 30 as measured by the E2 standard assay.

Guys get blood drawn, look at the test the next day, and say, "My E2 is at 44." Well maybe it was when the blood was drawn, but E2 can change by the moment. Have a beer; E2 goes up. Eat some oysters; E2 goes down. Maybe for whatever reason the boys made a little more Testosterone and E2 is up again.

I believe that some guys get into trouble thinking they need to have Anastrozole on a schedule. Become familiar with high E2 symptoms, and listen to your body.

I would like to heal the cause but I have no idea how... Can a vitamin D deficiency increase your E2 to these levels? I don't think so...

Vitamin D levels can turn on or off about 3,000 genes that we know of. I wouldn't have thought that low Vitamin D could cause back pain, but the video I posted the other day was by a doctor who found that poor sleep was resulting in back pain, and the poor sleep was a result of low Vitamin D.

If you are not a nudist, chances are your Vitamin D level is not optimal. And if you are a nudist and live above the 33rd parallel, you have been going without Vitamin D for quite a few months now.

If your Vitamin D level is low, maybe it's causing some problem, that is causing another, that is causing high E2.

Vitamin D is crucially important for your health and longevity. Get it checked!

PS: I was specifically told by the Admin of another forum to not use the Sensitive Estrogen test because it will give you a lower number than what you actually are...

Doctors that get the tough cases (such as Dr. Crisler and Dr. Gordon) are big proponents of the E2 sensitive assay. Although am a fan of them both, I don't agree with their arguments.

The E2 sensitive assay is not available where I live. My experience with the standard assay where I live is that it's accurate and consistent. Having said that, I don't rely on the test to take Anastrozole; I go by my symptoms.

[zempey]

If you have gyno and want to do adex, try .25 e3d, break the pill into 4 and take every 3rd day, that will give you close to what you are looking for. You want to be very careful not to crash your e2, try this dose for a week and go get a sensitive e2 test done to see how this dose reacts with your system. Trust me, I feel your pain, I am super prone to gyno, but you don't want to blindly take these strong medications without closely monitoring your blood work. The nolva will help control the lumps in your chest, but will also skew the blood results. Keep us posted, hope you get this under control.

[ssj4goku1992]

I will start with 0.125 mg EOD + the Nolva protocol for gyno. I will do blood tests in 3 weeks and see if I am good or I need to adjust the dose. Thanks!

[OingoBoingo]

I gotta get me some popcorn!

[Paragon73]

What 2Sox and OingoBoingo said. Also, .125 mg anastrazol eod is probably going to crash your E2 to an unhealthy level. It's that strong. Also consider the rebound effect of this drug. I also recommend trying some E2 reducing supplements, as you only need to reduce it a little bit and you need a healthy long-term solution. If the supplements don't work out, Exemestane is a better option for you, IMO. Paragon73 TRT 2.5 years

[2Sox]

Just a F.Y.I. from one of the "fanboys" of Aromasin who has experienced the rebound effect of Arimidex - on TRT. This is just one source but the information is readily available. No "myths", no opinions. Just fact.

Estrogen rebound: This is one of the Arimidex side effects that are very important to understand. It is a side effect generally unique to both Arimidex as well as Letrozole (Femara). The third major aromatase inhibitor, Aromasin (Exemestane) does not exhibit Estrogen rebound. This is because Arimidex and Letrozole are what is known as non-suicidal aromatase inhibitors. Aromasein (Exemestane) is a suicidal aromatase inhibitor. A suicidal aromatase inhibitor (such as Aromasin) indicates that once it has bound to the aromatase enzyme (and thereby inhibiting it), the inhibited enzyme remains bound to aromatase permanently, rendering the enzyme inactive forever. The body will eventually manufacture more aromatase enzymes, but the current bound enzymes are bound indefinitely, eliminating any risk for Estrogen rebound.

Non-suicidal aromatase inhibitors such as Arimidex and Letro, however, are only bound to the aromatase enzyme for limited time periods before the aromatase inhibitors unbind either due to natural metabolism, or through competition with other substrates. If a non-suicidal aromatase inhibitor is halted too abruptly, the circulating inhibited aromatase enzymes that have not been metabolized out of the body will then become free again, and begin aromatizing androgens into Estrogens at an often rapid rate. This is why it is advised to slowly halt administration of Arimidex, and/or slowly reduce the dose and/or frequency of the dose when stopping

From this link:
http://*******************/anti-estr...-side-effects/

It would be logical that this effect would be more extreme in AAS users but for those of us on TRT who have experienced this rebound and have had difficulty dosing and dealing with Arimidex, this effect cannot be denied. Of course, different individual's experiences with medications often vary greatly. And that experience is always what guides what medication an individual takes and is most comfortable with.

OP,
Unfortunately, for whatever reason, opinions sometimes come disguised as facts in some posts. The best advice I can give you is to distinguish one from the other on any forum you participate in. Then do whatever works for you.