Though I haven't run tren yet - I think nothing will compare to that compound(it's very harsh & some compound - the best I hear - but the highest sides to gains ratio too) but NPP my first run w/it I ran it at 420ish and prop 600(my BW was through the roof - 12,522ng/dl on that dose! Crazy high! But I think you can run it at least at 400 - my next run will be around 550ish w/test around the same(maybe 700 but from what I've gathered 600+ prop is just about the equivalent or close to the long esters) I'll see for myself soon
I hear that all the time about the breathing etc on tren and how hard it is to run it for long periods(at least one whose new to the game)