I am 48 yet have the body of a mid 30's have been in the gym again now for 4 years and even though I had a stroke in 2011 I have not let that stop me! I feel great and if you are 40 or over all I can say is get your butt out there and workout as hard as you can. I do heavy weight 3 times a week and legs 2 times a week then on the 4th day I do light weight for each body part. It works for meand I have gone from a mere 190lbs to a muscle bound 250lbs. So I am doing something right just hang there and just go for it!!!!!!!!!!!