This study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378070/ says that 250iu HCG EOD during TRT increased intratesticular testosterone compared to placebo but still 7% below baseline. At 500iu EOD it went above baseline. Well I inject E3D so at 500iu E3D it would seem I'd end up above baseline too (average 167mg/day). Why is it advocated to take the lower dose here on the forums though? Leydig cell desensitization doesn't happen until even higher dosages. The other side effect might be estrogen control but then I can just bump up to 25mg aromasin from 12.5mg.
Also another question about HCG, I bought Ovitrelle (r-HCG). I think this will be too expensive in the long run. It costs like $100 per 6500 iu while fertigyn 5000 iu costs $35. Wouldn't it be worth it for me to switch to fertigyn and go 500iu E3D along with my test cyp shots?