
Originally Posted by
GearHeaded
heres an example of why endogenous production of a hormone trumps endogenous production on a mg per mg basis.
- Bob decides to get on HGH. he spends a couple grand and runs 5iu for 6 months and has great results
- his neighbor Joe decides to do the same exact thing and also buys the HGH from the same source and takes the same dosage the same way.
but , Joe does not get any results. why not? the HGH was exactly the same and so was everything else in regards to dosing and timing.
well what likely happened is that Joe's body will only use endogenous HGH. when the exogenous HGH was introduced into the body, Joe having an underlying autoimmune response genetic condition, built up anti-bodies to the exo HGH. these anti-bodies found and destroyed or rendered useless the HGH he was taking. only the naturally produced HGH would work in Joes body.
Bob on the other hand had no such issue.
this is why there is so much argument as to wither different HGH sources or real or fake, or some guys get results and some guys don't get shit.. its because plenty of guys will only respond to natural HGH (thats why peptides work great for them).
similar thing can happen with any exogenous hormone introduced into the body..
but the point is that naturally occurring endogenous hormones are going to be way more powerful and "bio-avaialbe'' to be used by the body, and less likely to have anti bodies attack and destroy it like an outside invader.
thats why 50mg of naturally produced test can yield 700-900+ ng/dl of total test ,, where as 200mg of a UGL exogenous test cyp may not yield that much (and it may not be under dosed). we have the ester issues with the test cyp that need to be broken down properly by enzymes into the body in order to enter the blood stream, and we have anti bodies to worry about. even with a 14 day active life, that 200mg test cyp ultimately may not even get us 50mg of test to be utilized by the body.
the natty test doesn't have enzymes that are needed to break it down, anti bodies to kill it off, absorption rates, migration from the depot site of injection, possible encapsulation keeping it form entering the blood stream , etc etc..