LDL oxidizes and deposits plaque in the arteries over time, having a very high LDL is a guarantee of having a heart attack in 20-30 years.
So when taking steroids, we should do breaks and cruise with low test doses and take supplement (red yeast rice, niacin) untill the lipids returns to normal range, before blasting again.
This way you can live very old (like Arnold) and still use steroids. Not only that, but if you are constantly blasting, your receptors become saturated and downregulate, causing you to stop making any further progress. The duration of the cruise/blast cycle influences the intensity of the blasting, with the strength of the blast increasing the longer the cruise phase has been maintained.
Thanks so much man, this was the answer I was waiting for !!
As a chemist, I have tools to check the litterature and I found a lot of papers supporting this,
example :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497409/