So continuing on with studies on Egg Consumption.
Cholesterol
Using beta-sitosterol researchers have been able to reduce the absorption of cholesterol by as much as 42%, (further down the page) but do we really need to use beta-sitosterol if eggs already have lecithin to combat absorption of cholesterol.
The research by Sung I. Koo, Yonghzhi Jiang and Sang K. Noh has resulted in the issue of U.S. Patent No. 6,248,728, "Compositions and methods for lowering intestinal absorption and plasma levels of cholesterol." The patent was issued June 19 to the KSU Foundation.
A peer-reviewed research paper by the three researchers, "Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats," appears in the September issue of Journal of Nutrition.
Many people believe that dietary cholesterol directly contributes to raising blood cholesterol. Because eggs provide about half the dietary cholesterol in a typical Western diet, the public has been advised to limit its egg consumption.
Under the experimental conditions using an animal model that closely mimics human physiology, Koo and his associates found that a particular egg phospholipid interferes with the absorption of egg cholesterol and markedly lowers its uptake by the intestine. When the phospholipid is saturated, its inhibitory effect is further enhanced.
The researchers controlled experimental conditions to specifically look at egg phospholipid and its effect on cholesterol absorption. Even though a good amount of cholesterol is consumed when an egg is eaten, much of the cholesterol becomes "unavailable for absorption" in the presence of the phospholipid, Koo said.
"This may be a reason why so many studies found no association between egg intake and blood cholesterol," he said. The phospholipid, or lecithin, found in egg markedly inhibits the cholesterol absorption. The inhibition is not 100 percent, he said. Some cholesterol is absorbed but the amount is significantly reduced in the presence of this phospholipid.
"Less absorption means less cholesterol introduced into the blood," Koo said. "We were able to determine experimentally that a substantial amount of the egg cholesterol is not going into the blood stream."
The compounds are naturally occurring or derived from their natural precursors which could lead directly to development of new compounds for lowering cholesterol. Koo anticipates that regulatory barriers to such development will be low.
Koo says people with normal cholesterol levels and no family history of cardiovascular disease should not worry about eating one to two eggs a day. There's more overall nutritional benefit than harm to be gained from eating "nutrient-dense" eggs -- in moderation, he said.
Egg contains a higher quality protein than protein found in meat, milk or fish.
Furthermore, egg is a significant source of vitamins A and E, and B vitamins, B-6, B-12 and folate, which are known to lower blood levels of homocyst(e)ine, an independent risk factor for heart disease.
Koo's research has received support from the Kansas Agricultural Experiment Station and the USDA National Research Initiative Competitive Grants Program.
Koo is a professor of human nutrition at K-State; Jiang received a master's degree in nutrition from K-State; and Noh is a postdoctoral researcher at K-State who is continuing research with Koo.
Kansas State University (2001, October 29).
Eggs Have A Lipid That Lowers Cholesterol Absorption,
Kansas State University Nutrition
KS Researchers at Kansas State University have found the first in vivo evidence that a significant part of an egg's cholesterol is not absorbed. This could explain why eating one or two eggs a day has little or no effect on blood cholesterol and cardiovascular disease (CVD) risk, despite the high cholesterol content of eggs. This study of cholesterol absorption in rats appeared in the September 2001 issue of the Journal of Nutrition.1
In vitro studies have shown that phosphatidylcholine, found mainly in eggs and unrefined soy oil, inhibits cholesterol uptake by the intestine. When saturated, the phospholipid appears to have the greatest inhibitory effect on cholesterol absorption. It is still unclear, however, how and why phosphatidylcholine interferes with cholesterol absorption, and whether normal dietary intake of the substance is sufficient to achieve this inhibition.
First study in animals
Yongzhi Jiang (Kansas State University, Manhattan, KS) and his colleagues performed the first in vivo study of the effects of egg and soy phosphatidylcholine, which differ in saturation, on intestinal cholesterol absorption. They infused rats with a lipid emulsion containing either soy- (mostly unsaturated fatty acids [FA]), egg yolk-(mostly saturated and monounsaturated FA) or hydrogenated egg yolk (only saturated FA) phosphatidylcholine and measured lymphatic cholesterol absorption in each group over 8 hours.
Cholesterol absorption was significantly lower in rats infused with egg phosphatidylcholine, but significantly higher in those with soy phosphatidylcholine, compared to the control group. The inhibitory effect was further enhanced when the phosphatidylcholine was hydrogenated.
Lymphatic cholesterol absorption in rats 8 hours after infusion
Study group
% Cholesterol absorbed
Not infused with phosphatidylcholine
30.8%
Infused with soy phosphatidylcholine
34.9%
Infused with egg phosphatidylcholine
24.7%
Infused with hydrogenated egg phosphatidylcholine
21.1%
Not all phosphatidylcholines are equal
These findings lead the researchers to the conclusion that phosphatidylcholine-mediated suppression of cholesterol absorption depends on the degree of saturation of its acetyl group. "The lymphatic absorption of cholesterol decreased with increasing saturation of the phosphatidylcholine infused," they write. In an interview with heartwire, co-author Sung I Koo (Kansas State University) explained that, although soy phosphatidylcholine promoted cholesterol absorption at the dosage levels used in this study, it may well have an inhibitory effect at a higher dose.
The researchers point out that their study still did not uncover the exact mechanism underlying the inhibitory effect of phosphatidylcholine on cholesterol absorption. Koo illustrated two possibilities of interaction. Phosphatidylcholine could interfere with fat digestion, which is necessary to facilitate the entry of cholesterol into the intestinal absorptive cell. The inhibitory effect could also be related to "tight hydrophobic interactions between phospholipid and cholesterol in micellar matrix, which render cholesterol less available for cell uptake," Koo explained.
New ways to lower blood cholesterol?
We cannot directly extrapolate findings to humans, but postulate that it also might occur in humans.
If these findings prove to be applicable in humans, they may explain the fact that, although egg yolk contains high levels of cholesterol (260 mg), consuming one or two eggs per day does not increase blood cholesterol levels and CVD risk. Egg yolk contains high levels of phosphatidylcholine (1.3g), which might significantly lower the intestinal uptake of egg cholesterol in humans as well. "Although our study is the first in vivo study using an animal model, we cannot directly extrapolate findings to humans, but postulate that it also might occur in humans," said Koo. If it does, the inhibitory effect of phosphatidylcholine on cholesterol absorption could translate into the development of new agents to lower blood cholesterol, Koo said.
Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats.
US National Library of Medicine National Institutes of Health
So we are going from egg yolks being bad to egg yolks lowering your cholesterol? WTF? People really need to do their research before arguing for egg whites or taking eggs out of their diet completely.
“Optimizing the effect of plant sterols on cholesterol absorption in man.”
F H Mattson, S M Grundy, and J R Crouse
Abstract
During three experimental periods, nine adults were hospitalized on a metabolic ward and fed a meal containing 500 mg of cholesterol as a component of scrambled eggs. In addition, the meal contained: 1) no additive, 2) 1 g beta-sitosterol, or
3) 2 g beta-sitosteryl oleate. Stools for the succeeding 5 days were analyzed to determine the percentage of the cholesterol in the test meal that was absorbed. The addition of beta-sitosterol resulted in a 42% decrease in cholesterol absorption; the beta-sitosteryl oleate caused a 33% reduction. These results indicate that the judicious addition of beta-sitosterol or beta-sitosteryl oleate to meals containing cholesterol-rich foods will result in a significant decrease in cholesterol absorption, with a consequent decrease in plasma cholesterol.
The American Journal of Clinical Nutrition
ajcn.nutrition.org
These B-Sitosterols’ can be bought at your local vitamin/supplement shop OTC.
beta-Sitosterol
β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol. Sitosterols are white, waxy powders with a characteristic odor. They are hydrophobic and soluble in alcohols.
It is widely distributed in the plant kingdom and found in Nigella sativa, pecans, Serenoa repens (saw palmetto), avocados, Cucurbita pepo (pumpkin seed), Pygeum africanum, cashew fruit, rice bran, wheat germ, corn oils, soybeans, sea-buckthorn, wolfberries, Cannabis sativa and Wrightia tinctoria.[citation needed] It is also found in dandelion coffee.
Precursor of anabolic steroid boldenone
Being a steroid, β-sitosterol is precursor of anabolic steroid boldenone. Boldenone undecylenate is commonly used in veterinary medicine to induce growth in cattle but it is also one of the most commonly abused anabolic steroids in sports. This led to suspicion that some athletes testing positive on boldenone undecylenate didn't actually abuse the hormone itself but consumed food rich in β-sitosterol. (FUNNY)
Wiki.org
It’s funny how steroids are related to improving general health but you don’t see that advertised anywhere.
Fat Intake
“Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials”
Ronald P Mensink, Peter L Zock, Arnold DM Kester, and Martijn B Katan
Background: The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their effects on LDL cholesterol. Fats, however, also affect HDL cholesterol, and the ratio of total to HDL cholesterol is a more specific marker of CAD than is LDL cholesterol.
Objective: The objective was to evaluate the effects of individual fatty acids on the ratis of total to HDL cholesterol and on serum lipoproteins.
Design: We performed a meta-analysis of 60 selected trials and calculated the effects of the amount and type of fat on total:HDL cholesterol and on other lipids.
Results: The ratio did not change if carbohydrates replaced saturated fatty acids, but it decreased if cis unsaturated fatty acids replaced saturated fatty acids. The effect on total:HDL cholesterol of replacing trans fatty acids with a mix of carbohydrates and cis unsaturated fatty acids was almost twice as large as that of replacing saturated fatty acids. Lauric acid greatly increased total cholesterol, but much of its effect was on HDL cholesterol. Consequently, oils rich in lauric acid decreased the ratio of total to HDL cholesterol. Myristic and palmitic acids had little effect on the ratio, and stearic acid reduced the ratio slightly. Replacing fats with carbohydrates increased fasting triacylglycerol concentrations.
Conclusions: The effects of dietary fats on total:HDL cholesterol may differ markedly from their effects on LDL. The effects of fats on these risk markers should not in themselves be considered to reflect changes in risk but should be confirmed by prospective observational studies or clinical trials. By that standard, risk is reduced most effectively when trans fatty acids and saturated fatty acids are replaced with cis unsaturated fatty acids. The effects of carbohydrates and of lauric acid–rich fats on CAD risk remain uncertain.
The American Journal of Clinical Nutrition
A large egg contains about 5 grams of fat – about 1.5 grams saturated and 2.6 grams unsaturated, so if we use eggs as a primary fat source we are actually decreasing our risk of heart disease (CVD)(CAD)??
USDA NUTRIENT DATABASE
Chicken egg - whole, hard-boiled
Nutritional value per 100 g (3.5 oz) (that’s 2 eggs for the mathematically challenged)
Energy 647 kJ (155 kcal)
Carbohydrates 1.12 g
Fat 10.6 g
Protein 12.6 g
- Tryptophan 0.153 g
- Threonine 0.604 g
- Isoleucine 0.686 g
- Leucine 1.075 g
- Lysine 0.904 g
- Methionine 0.392 g
- Cystine 0.292 g
- Phenylalanine 0.668 g
- Tyrosine 0.513 g
- Valine 0.767 g
- Arginine 0.755 g
- Histidine 0.298 g
- Alanine 0.700 g
- Aspartic acid 1.264 g
- Glutamic acid 1.644 g
- Glycine 0.423 g
- Proline 0.501 g
- Serine 0.936 g
Water 75 g
Vitamin A equiv. 149 μg (19%)
Thiamine (vit. B1) 0.066 mg (6%)
Riboflavin (vit. B2) 0.5 mg (42%)
Pantothenic acid (B5) 1.4 mg (28%)
Folate (vit. B9) 44 μg (11%)
Vitamin B12 1.11 μg (46%)
Choline 294 mg (60%)
Vitamin D 87 IU (15%)
Vitamin E 1.03 mg (7%)
Calcium 50 mg (5%)
Iron 1.2 mg (9%)
Magnesium 10 mg (3%)
Phosphorus 172 mg (25%)
Potassium 126 mg (3%)
Zinc 1.0 mg (11%)
Cholesterol 424 mg
Chicken eggs are the most commonly eaten eggs. They supply all essential amino acids for humans (a source of 'complete protein'), and provide several vitamins and minerals, including retinol (vitamin A), riboflavin (vitamin B2), folic acid (vitamin B9), vitamin B6, vitamin B12, choline, iron, calcium, phosphorus and potassium. Although not as abundant as red meats, eggs are a source of CoQ10 depending on how they are prepared.
All of the egg's vitamins A, D, and E are in the egg yolk. The egg is one of the few foods to naturally contain vitamin D. A large egg yolk contains approximately 60 Calories (250 kilojoules); the egg white contains about 15 Calories (60 kilojoules). A large yolk contains more than two-thirds of the recommended daily intake of 300 mg of cholesterol (although one study indicates the human body may not absorb much cholesterol from eggs). The yolk makes up about 33% of the liquid weight of the egg. It contains all of the fat, slightly less than half of the protein, and most of the other nutrients. It also contains all of the choline, and one yolk contains approximately half of the recommended daily intake. Choline is an important nutrient for development of the brain, and is said to be important for pregnant and nursing women to ensure healthy fetal brain development.
The diet of the laying hens can greatly affect the nutritional quality of the eggs. For instance, chicken eggs that are especially high in omega 3 fatty acids are produced by feeding laying hens a diet containing polyunsaturated fats and kelp meal. Pasture-raised free-range hens which forage largely for their own food also tend to produce eggs with higher nutritional quality in having less cholesterol and fats while being several times higher in vitamins and omega 3 fatty acids than standard factory eggs. Focusing on the protein and crude fat content, a 2010 USDA study determined there were no significant differences of these two macronutrients in consumer chicken eggs.
From your friendly wiki.org
Sources check out.
With all that being said is there any other questions or concerns about egg consumption? Of course everything is good in moderation but removing egg yolks is just an absurd idea.
My personal consumption of 18-24 raw eggs daily has not had any adverse effects on my HDL/LDL levels, as a matter of fact I gave up protein shakes and increased egg intake and I started gaining mass quickly without any noticeable increase in BF%.
SO EAT YOUR EGGS DAMMIT