Thanks for the tangible information. AFter I posted this I got Dr. Crisler's protocol for TRT and then went onto some medical sites and started to research the chemistry and biology of what occurs. I'm getting blood to day or tomorrow from Crisler's suggestions as well as a dozen others if my doc will order them to see what is really going on with me. I know my T4 and T3 are at high levels (near top) and my TSH is very low (near bottom) identifying that it isn't my thyroid unless a REVERSE T3 is occuring preventing increases is tissue thyroid levels. After continued research I will definitely do as you and Dr. Crisler recommends 100mg test once weekly for 5 weeks - do blood tests - look at estriole E2, free test, bioavailable test - then add HCG of 250 IU 2 days preceding the test shot - then after another month check estriole and if necessary add that .25 e3d. The clomid and the anastrozole have different mechanisms. For insance when the HCG is too high, it affects blood estrogen levels thus the needs for an Aromatase Inhibitor like anastrozole. THe clomid is a SERM - Selective Estrogen Receptor Modulator preventing atagonistic estrogen from being assimilated as it blocks it's uptatke at the receptor level.
Please post your suggestion for a TRT / Anti Aging regime. I have not found any detiled information about this anywhere in the for that Dr. Crisler has provided. Easily understood, planned, what to look for, etc.
Look forward to your posts and knowledge about this. I'll get my lab tests taken soon. I have very high liver enzymes due to tylenol poisoning 5 years ago. I have very high cholesterol. Low DHEAS, High Cortisol. I thnk that I suffered from an almost complete breakdown of the Adrenal, Hypothalmus, Thyroid, Pituitary Axis. There is an excellent site called Thyroid Disease Manager located at
http://www.thyroidmanager.org/ which gives very excellent detailed scientific information which I am able to assimilate due to my medical billing experience. My company has done outsourced medical billing and medical office management as a part of our services lineup before I got sick. Terrific Site sponsored by the company that makes Synthroid. I learned a lot about the HPTA axis there that I found nowhere else. The acttual mechamism - here is the link to the document in pdf form for those who want information about the thyroid -
http://www.thyroidmanager.org/chapter4/chapter4.pdf. If you replace the chapter 4 with a 1 in both places
http://www.thyroidmanager.org/chapter1/chapter1.pdf and so forth you'll get the entire textbook. THe chapters available are 1, 2, 4, 7, 8, 9, 10, 11, 12, 14, 15, 17, 19, 20 and 21. Just change the number and download the entire textbook on thyroid issues. This is a college medical textbook on the subject so be aware that the entire discipline if covered in the most detailed biological and chemical terms down to the cellular levels. It is heady but if you are able to understand some of it, you'll come away with a more complete understanding of the mechamism and interrelationships of the THyroid with the Hypothalmus, Adrenal, Pituitary systems.
Hope I wasn't too boring and off point.
Look forward to additional suggestions about Anti Aging, Hormone Replacement and other related issues.