
Originally Posted by
meathead320
Hi all,
For those who have been here over the last year, I had some issues with ED and low libido, E2 control and so forth.
I tried a lot of different things, and figured out a protocol that has been working for me quite well.
I had been as high as 300mg EW, wich is really more low dose AAS cruising, and eventually even on just test you can start to feel like crap. One of the things I found is that consistent levels of high test will eventually desensitize D2 dopamine receptors in the brain.
Maybe not in all patients, but certainly in my case. It was killing my libido. Pretty much like Deca dick, but from too much test, and being on higher dose than one should really be on for TRT for too long.
I tried a few different things, but because of that dopamine insensitivity not even Caber would work.
Tried changing the test dose to a more conservative amount, yet still was having libido. It was as if 100mg just could not work as I was used to more than that, but more than that would not work as I was burned out on "more".
So I consulted with a couple different doctors, one a neurologist, and a psychologist to find out how long it takes for D2, or dopamine sites to recover from over stimulation.
Well, GOOD NEWS, it turned out the have some experience with this from patients they have had on L-Dopa, and even drugs like wellbutrin, which is a re-uptake inhibitor, and these drugs lead to too much circulation, and eventual loss of sensitivity. There is however a re-sensitizing process that is much shorter than it takes to become desensitized. The docs I talked to said there has been no clinical studies on the amount of time it takes to regain sensitivity, but in their practice taking people off of these drugs for 30 days usually does the trick, and the educated guess was that the ratio is about 1/8, or 8x as long to lose sensitivity as it takes to regain it.
So, I went off the TRT completely. Ran a PCT same as I would going off of an AAS cycle.
Took 100mcg of triptoraline followed by clomid at 25mg ED x 30 days.
Stayed off another 15 days. Had blood work done, and my test was low but about where it was when started TRT.
Went back on TRT, after having been off a total of 45 days. Figuring my dopamine receptors had recovered, I would be more conservative with the TRT this time, and not treat is like AAS use.
New protocol:
Testosterone Cypionate IM 100mg 1x EW on Monday morning.
Anastrozole 0.25mg 2x EW Monday and Thursday evening.
10mg of Clomid 1x EW on day of shot
The Clomid is likely too infrequent and low dose to cause sides. For some reason it lowers my BP a bit and has strong positive effect on my HDL values, so I figured what harm is there in such a small dose of it spread out long term?
I also wont use HCG as the reason I’m on TRT is primary testicular trauma. Initial work up found highly elevated LH and FSH levels, so not much good putting in an LH agonist would do.
The reason for the 100mg only 1x per week is that too consistent levels of test and I don’t feel it as much. Where if it has a chance to get a little low, that may be helping me with the D2 sensitivity.
So far I’ve been on this protocol about 60 days, and have been feeling great. Good libido, high energy.
If the cheese ever slides off the cracker again in terms of my libido, I’ll take another 30 day break. Hate having to do that, but it sure made a difference for me.
I don’t think this would have been as effective a protocol had I not just let my system take a break to “reset”.