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Thread: AI dose timing

  1. #1
    fjr02 is offline Junior Member
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    AI dose timing

    Is there a good rule of thumb as to when I should take AI with consideration of when my T shots are?

    I have the option of doing 120mg/week or 60mg twice per week (T Cyp).
    My doc has me on A-dex 0.25mg twice per week.

    Under the two shot scenario, he told me to take the AI on the same days as the shot just to make it easy.

    Does it matter when the AI is taken?

    thanks

  2. #2
    bass's Avatar
    bass is offline HRT Specialist ~ Knowledgeable Member
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    most of us take it 12-24 hours after injection. twice a week is the best way to control E2, less AI, less sides, more money in your pocket!

  3. #3
    HRTstudent's Avatar
    HRTstudent is offline HRT Specialist ~ Knowledgeable Member
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    Quote Originally Posted by bass View Post
    most of us take it 12-24 hours after injection. twice a week is the best way to control E2, less AI, less sides, more money in your pocket!
    this is how a lot of people do it... basically try to time the peak of T with the AI. AI is very tricky though and it's really a trial and error thing. everyone is different.

    I believe arimidex peaks in the blood around 4'ish hours after ingestion. half life is around 45 hours as well.

  4. #4
    Logonzo is offline New Member
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    24 hrs after shot works well for me. Same dosages as yourself, not that it means much lol.

  5. #5
    jamotech's Avatar
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    I am starting to go past 24hrs, like 30.

  6. #6
    keep fightin is offline Associate Member
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    Im goin 50x2ew of T SQ and .25mg adex 12 hrs after shot, really feel dialed in right now

  7. #7
    DGK
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    what do u guys rec for ai dosage when on trt. I use to take 12.5 mg eod when on cycle. I use liquid stane,,, im on 200 mg test cyp every two weeks

  8. #8
    fjr02 is offline Junior Member
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    After 3 weeks on Cyp & AI, I noticed some breast tenderness, so I increased by AI dose.
    I am on 60mg Cyp twice per week. After the AI adjustment, I am now taking 0.25mg on and after the injection day. (0.25mg 4 times per week).
    Should I simply do 0.5mg the day after the injection?

    Is 1mg per week still a reasonable number?

    thanks

  9. #9
    durak's Avatar
    durak is offline Member
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    If you can, get your e2 tested. Truth is everyone is different. .5mg 2x week is not outlandish but without testing you are just throwing darts.

  10. #10
    durak's Avatar
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    I got tenderness when starting try and it still comes and goes. Thankfully, it never progressed to gyno.

  11. #11
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by durak View Post
    If you can, get your e2 tested. Truth is everyone is different. .5mg 2x week is not outlandish but without testing you are just throwing darts.
    Exactly what durak said. There is no "rule of thumb" as everyone metabolizes differently. Get tested a couple months in a row to figure it out.

  12. #12
    fjr02 is offline Junior Member
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    I'm not really throwing darts.
    My estradiol is 16, I have a script for an AI, and I've been taking less that the Dr has suggested to take.
    I wanted to start the AI low and figure out what dosage would be the minimum to address my sides and stay there.
    Apparently even with a low estradiol, I still get the sides.

    Sounds like 1mg/week is not excessive, and I'll try changing my AI to two 0.5mg doses timed as described earlier.

  13. #13
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    I do 60 mg times 2 per week also. No AI as I apparentely am a low aromatizer. My E runs steady at 15-16 confirmed by BW three months in a row. I also consider myself nip sensitive. I would think the sensitivity you experienced was just your body adapting to the new substances. Do you still have sensitivity?

    I would consider eliminating the AI entirely or reducing it even more for a while and see what happens based on BW and how you feel. I know, its scary. You can always get some nolvadex on stand by if you think your levels will spike. It will allow your E to raise and eliminate any chest receptor issues. You will probably feel better in the 20's with your E level. I hope to raise mine somehow!

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