I am not sure that I can identify an [sic] unifying diagnosis for all
the above-mentioned signs and symptoms. It does appear he has hypothyroidism and
needs to be on Synthroid. I suspect if hit remains hypothyroid, then the dose will need
to be incrused. This is likely related to autoimmune disease.
His vitamin D deficiency is mild, but could be related to gluten sensitivity. I will recheck
his 25-hydroxy vitamin D level and chemistry panel today as well as to obtain tissue
transglutaminase antibodies. This could then tie in with the thyroid disease.
In terms of the hypogonadism, his GU exam showed a normal phallus and normal
testes.
I think this would be acquired hypogonadism. He also has normal male hair
pattern. I will repeat his bioavailable testosterone along with LH and FSH. It is possible
that with his obesity, he has estrogen effect in his SHBG and his free testosterone is
actually normal. I will also check a prolactin level.
His abdominal striae could indicate hypercorticolism. I have asked that he do a 24-hour
urine free cortisol. This could account for the hypogonadism, but would not account
for the hypothyroidism or vitamin D deficiency. Hence, again this may be an issue, but
It is not a unifying diagnosis.