Every since starting trt and getting my test and estro levels up, caffeine doesn't seem to have much effect if any at all. I feel like this has to do with having a lot of anxiety with lower T and E levels. Now my hormones look great but I can drink a cup of coffee and go right back to sleep. In July I could have a cup of coffee and be wired for hours. The other day I took 270mgs of caffeine from C4 pre workout and barely felt a thing. This started happening exactly at the same time I started with injections so I don't believe it's a coincidence. I'm going to ditch the caffeine as it doesn't really have any effect anymore. Wondering if maybe it adrenal fatigue as I'm tired all the time, my dhea was low on last blood test (although cortisol was 13 at 1pm which seemed good). I wake up and have energy for about 45 minutes then I'm tired until I get a surge of energy around 5-6pm for a few hours. Started supplementing with 50mg micro dhea and preg but still feel fatigued.