A new observational study following men with hypogonadism taking testosterone for 5 years — the longest treatment duration to date — showed improvements in lipids, blood pressure, and blood glucose levels, thereby ameliorating a number of components of the metabolic syndrome.
"Men with hypogonadism, or testosterone deficiency, do get reasonable benefit from testosterone treatment, in a very subtle way," lead author Adulmaged M Traish, PhD, from Boston University School of Medicine, Massachusetts, told Medscape Medical News. "They lose a bit of weight, it reduces hyperglycemia and insulin resistance, and, although it was a surprise to me, testosterone certainly normalizes the lipid profile."
The long duration of this new trial strengthens the findings, said Dr. Traish. "If this were a 3-week or 6-week observational study, I would have my personal doubts, but once you pass the third or fourth year and it stays consistent, it's beginning to tell us that there is something obviously there."
http://www.medscape.com/viewarticle/813327