Why do i feel like crap? Recently started TRT

Why do i feel like crap? Low wellbeing and insecure. :madd:

Started TRT 16 weeks ago. 1gram Nebido, six weeks later one more. eight weeks later one more. Now its two weeks ago last shot.

I take 0.33 adex EOD for estrogen controll.

I feel much worst now then before therapy with only 250ng/dl in my blood.

What can make me feel low? Is it the ADEX? Do i need hcg? Is it just an waiting game?
Please come with some wise advice, i really appreciate it.

Nebido takes a lot too "kick in". This is due to its slow-release nature. Oestrogen is hard to control due to levels being high in the start and low in the end... what does bloodwork says?

I've been more than a year on Nebido, worked great but was inconsistent over time.

Nothing to do with HCG.
Nebido has a 3 month halflife and is acting superslow. But 16 weeks, ill bet you should feel it by now.
You run O,33 mg adex each day?
That dose is often used for 500 mg test a week. And way too much for trt.

Best solution is ofcourse BW. If you dont want to do that, i think i would try of o,25 mg adex eod. or less too if your bodyfat is below 15%

You shouldn't need an ai on nebido. Does bloodwork suggest you do? If not, drop it.

HCG would be a welcome addition, 250iu's x 2 pw.

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Originally Posted by Silabolin

Nothing to do with HCG.
Nebido has a 3 month halflife and is acting superslow. But 16 weeks, ill bet you should feel it by now.
You run O,33 mg adex each day?
That dose is often used for 500 mg test a week. And way too much for trt.

Best solution is ofcourse BW. If you dont want to do that, i think i would try of o,25 mg adex eod. or less too if your bodyfat is below 15%

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AI is probably overdosed indeed. TU won't aromatize a lot like test C/E due to slower ester cleavage. Anyway t/2 is about five weeks, three months is the average interval between injections.

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Originally Posted by bizzarro

AI is probably overdosed indeed. TU won't aromatize a lot like test C/E due to slower ester cleavage. Anyway t/2 is about five weeks, three months is the average interval between injections.

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Nebido Functions & Traits:

Nebido is a pure testosterone hormone attached to the very large Undecanoate ester (Testosterone Undecanoate). The ester is attached to the hormone in order to regulate its release pattern, but it does not affect the testosterone hormones mode of action in anyway. The functions and traits of Nebido on a hormonal basis will be the same as all testosterone compounds.

Nebido, as a testosterone hormone, like all testosterone hormones carries an anabolic rating of 100 as well as an androgenic rating of 100. This is an estrogenic anabolic steroid in that it does aromatize at a fairly significant rate. As a testosterone compound, Nebido will also carry one of the longest half-lives of any testosterone or anabolic steroid available. Nebido carries an active half-life of approximately three months. Compare this to the more popular Testosterone Cypionate and Testosterone Enanthate, which both carry half-lives a little greater than a week and you can begin to understand how slowly acting Nebido will be.

What is the cause for your hypogonadism?

At your age it is not normal, yes it might be too much AI, but if you have underlying condition causing low T, no amount of testosterone is going to fix it.

Quote:

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Originally Posted by Silabolin

Nebido Functions & Traits:

Nebido is a pure testosterone hormone attached to the very large Undecanoate ester (Testosterone Undecanoate). The ester is attached to the hormone in order to regulate its release pattern, but it does not affect the testosterone hormones mode of action in anyway. The functions and traits of Nebido on a hormonal basis will be the same as all testosterone compounds.

Nebido, as a testosterone hormone, like all testosterone hormones carries an anabolic rating of 100 as well as an androgenic rating of 100. This is an estrogenic anabolic steroid in that it does aromatize at a fairly significant rate. As a testosterone compound, Nebido will also carry one of the longest half-lives of any testosterone or anabolic steroid available. Nebido carries an active half-life of approximately three months. Compare this to the more popular Testosterone Cypionate and Testosterone Enanthate, which both carry half-lives a little greater than a week and you can begin to understand how slowly acting Nebido will be.

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Perhaps. Half life just seems to vary a lot between studies.

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Originally Posted by bizzarro

Perhaps. Half life just seems to vary a lot between studies.

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If I'm not mistaken, and I may be, some sources list the half life (time it takes for the plasma concentration to be reduced by 50%), and some studies state the terminal half life (time it takes for slowest decrease in the plasma concentration of a drug down to 50%). I'm considering going on Aveed in the future and ran across what seemed to be contrary data.
Also, to second what BiB said, an AI is rarely needed with this ester of testosterone. There is supposedly much less conversion to E2, little need for dose titration, and it also seems to less prone to causing polycythemia, particularly in older males like myself that tend towards polycythemia.
At least those were some of the aspects my Dr. was interested in, particularly in my case.

Steroid abuse since 20y old. Now 29. My HPTA will not function the way its supposed to.

Yoiu guys have some other tips for me what can help me in the wellbeing part?

Quote:

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Originally Posted by Mr.BB

What is the cause for your hypogonadism?

At your age it is not normal, yes it might be too much AI, but if you have underlying condition causing low T, no amount of testosterone is going to fix it.

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Quote:

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Originally Posted by almostgone

If I'm not mistaken, and I may be, some sources list the half life (time it takes for the plasma concentration to be reduced by 50%), and some studies state the terminal half life (time it takes for slowest decrease in the plasma concentration of a drug down to 50%). I'm considering going on Aveed in the future and ran across what seemed to be contrary data.
Also, to second what BiB said, an AI is rarely needed with this ester of testosterone. There is supposedly much less conversion to E2, little need for dose titration, and it also seems to less prone to causing polycythemia, particularly in older males like myself that tend towards polycythemia.
At least those were some of the aspects my Dr. was interested in, particularly in my case.

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It will definitely work for erythrocytosis. I developed mild anaemia (Hb 12.0) with low t and it did took nebido a whole year to raise it to 13.5 .

The degree of aromatization obv depends on peak levels, and those seems to vary greatly between individuals. A single shot was enough for me to reach levels above detectable range for immunoassay (my lab reports >13.50 ng/ml).

I'm in a similar boat as you. I have primary hypo due to AAS abuse in my early 20's. I think you should try hcg, 250iu 2x/wk. I'm on week 2 of it (been on trt for 5 months now) and I can already feel a huge difference. Other than that, just give it time.

I would personally drop the adex completely. Thats just my opinion