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Thread: Going from Aromasin to Arimidex on 200 mg/ wk

  1. #1
    booku is offline Associate Member
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    Going from Aromasin to Arimidex on 200 mg/ wk

    I have used 200 mg/ wk of Test with 6.25 mg of Aromasin twice a week and this puts my estrogen at a good level. I want to try arimidex because Dr Crisler believes it is better for mental/brain health. What dose would I try with 200 mg of T ? 0.25 mg twice a week ? Or is it weaker ? I will get bloodwork to confirm just dont really know where to start dose wise

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    hammerheart is offline Knowledgeable Member
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    Stick to aromasin . If it ain't broken, don't fix it.

    The dose you are taking shouldn't trigger any particular issue, but swapping AIs potentially could.

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    booku is offline Associate Member
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    Quote Originally Posted by bizzarro View Post
    Stick to aromasin . If it ain't broken, don't fix it.

    The dose you are taking shouldn't trigger any particular issue, but swapping AIs potentially could.
    It is broken, again, do you have any anecdotal knowledge on dosages just dont want to start off in left field, I already have it on hand Im doing it

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    Quote Originally Posted by booku View Post
    I have used 200 mg/ wk of Test with 6.25 mg of Aromasin twice a week and this puts my estrogen at a good level. I want to try arimidex because Dr Crisler believes it is better for mental/brain health. What dose would I try with 200 mg of T ? 0.25 mg twice a week ? Or is it weaker ? I will get bloodwork to confirm just dont really know where to start dose wise
    I been told .25 every other day. Arimidex ...

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    bullshark99 is offline Member
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    Arimidex is strong, I would start with .25 the day after injection and .25 3 days later. Obviously adjust later with BW but that may do it.

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    Quote Originally Posted by booku View Post
    I have used 200 mg/ wk of Test with 6.25 mg of Aromasin twice a week and this puts my estrogen at a good level. I want to try arimidex because Dr Crisler believes it is better for mental/brain health. What dose would I try with 200 mg of T ? 0.25 mg twice a week ? Or is it weaker ? I will get bloodwork to confirm just dont really know where to start dose wise
    All the studies I've seen point in opposite direction, any studies or trials to back that claim?

    The best would be reduce the dosage so you dont even need an AI.
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    dreadnok89 is offline Member
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    Quote Originally Posted by Mr.BB View Post

    All the studies I've seen point in opposite direction, any studies or trials to back that claim?

    The best would be reduce the dosage so you dont even need an AI.
    Ya, aromasin is alot more forgiving. I also read it has better benefits too. I have read arimidex wrecks havoc on your lipids

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    Quote Originally Posted by dreadnok89 View Post

    Ya, aromasin is alot more forgiving. I also read it has better benefits too. I have read arimidex wrecks havoc on your lipids
    150mg/wk along with 500iu hcg caused my estrogen to spike too much. Aromasin @ 6.25mg twice a week sorted my e2 levels out ok within just few weeks. But since I stopped taking hcg I no longer feel need of AI, also now dropped to 125mg/week. 200mg/week is real high for trt

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    Quote Originally Posted by dreadnok89 View Post
    Ya, aromasin is alot more forgiving. I also read it has better benefits too. I have read arimidex wrecks havoc on your lipids
    It isn't. Exemestane is powerful stuff, and you can severely crush E2 with it. Its lipophilicity facilitates entry into the brain, potentially altering neurosteroids balance.

    That one study performed on males showing positive/neutral effects on lipid profile and IGF-1 is only ten days long, if I remember right. Just too short to reveal any negative outcome.
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    I dont doubt Aromasin /Exemestane is powerful thing and effects do take place rapidly when on it, in the first week on it I began to feel pain in my knees elbows and all joints in general, during that week my E2 sides went away (could say rapidly), and 1 more week later I had quit AI because joint discomfort was getting just really bad, I believe I may have landed my E2 too low while on Aromasin/Exemestane, way below the low-normal range where I should be.
    After stopping AI I kept taking HCG during the next week (during which I began to feel a relief on my joints, maybe HCG helped bounce back some of E2...not sure) and then went in to give bloods which showed just few points above higher limit, mind you - I have been taking nolvadex along side of AI and HCG to kill nipple sensitivity quick during those 2 weeks, which worked marvellously, so I too believe my E2 may have been little out of line (artificially elevated) because of nolva taken for two weeks before bloods. Although I have no water retention problems or other E2 sides since I stopped AI and later stopped HCG, I feel good and all is fine till this day, I however lowered my test dose now and will continue on for another while till next bloods in the future.

    Next time around I may give a try to Arimidex ... if it comes to the need of AI that is...

  11. #11
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    Quote Originally Posted by InsaneMuscle View Post
    I dont doubt Aromasin /Exemestane is powerful thing and effects do take place rapidly when on it, in the first week on it I began to feel pain in my knees elbows and all joints in general, during that week my E2 sides went away (could say rapidly), and 1 more week later I had quit AI because joint discomfort was getting just really bad, I believe I may have landed my E2 too low while on Aromasin/Exemestane, way below the low-normal range where I should be.
    Next bloodwork test uric acid. Joint pain comes from uric crystals depositing in joints without the protective effect of estrogen, its called gout.

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    InternalFire is offline Anabolic Member
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    Quote Originally Posted by Mr.BB View Post

    Next bloodwork test uric acid. Joint pain comes from uric crystals depositing in joints without the protective effect of estrogen, its called gout.
    Noted. Prevention for this?

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    I had not heard low estrogen causes gout? I thought potential liver problems could cause that? I am on 1 mg armidex per week taking 200 mg test cyponate per week.

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    Quote Originally Posted by JKW View Post
    I had not heard low estrogen causes gout? I thought potential liver problems could cause that? I am on 1 mg armidex per week taking 200 mg test cyponate per week.
    That's quite a hefty dose!
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    Quote Originally Posted by JKW View Post
    I had not heard low estrogen causes gout? I thought potential liver problems could cause that? I am on 1 mg armidex per week taking 200 mg test cyponate per week.
    So, what is the cause for the joint pain ppl complain associated with low estrogen?

    Just trying to understand it, I have not find any other explanation for it. Estrogen has a protective effect against urate crystals, premenopausal females are virtually gout free.
    Estrogen has no effect on synovial fluid, and other joint pains (that I know of) are all associated with wear and tear which doesnt explain this low estrogen joint pain.

    And liver problems are not the cause of gout.

    You might want to split that 1mg in 2x0,5mg/week
    Last edited by Mr.BB; 09-07-2016 at 03:30 AM.

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    Quote Originally Posted by bizzarro View Post
    It isn't. Exemestane is powerful stuff, and you can severely crush E2 with it. Its lipophilicity facilitates entry into the brain, potentially altering neurosteroids balance.

    That one study performed on males showing positive/neutral effects on lipid profile and IGF-1 is only ten days long, if I remember right. Just too short to reveal any negative outcome.
    Yes see this is exactly why I want to try arimidex Also:

    Aromasin : Significantly decreases both E1 and E2
    Arimidex : Decreases E1 , and only moderately decreases E2, BUT, according to Crisler, E1 is already rock bottom anyways from injecting the exogenous Testosterone , so as you can see, what you are getting with arimidex basically is a weaker form of aromasin that does not cross the blood brain barrier, and is probably more suitable for HRT , but if you are running high doses, you may require aromasin simply because you need something stronger, I think MANY men in general are being misled into thinking that somehow aromasin is far superior on Lipids (marginal at best with chronicity of use), hence they choose Aromasin over Adex, not accounting for the fact that their mental health and mood might be significantly better on Adex , and isn't that more of the goal here?? Not some bolony HDL number that fluctuates down 5-10 points ?

    I think this is the main reason why Crisler shys away from Aromasin, it would be nice if we could get some long term studies on the brain in MEN on anti estrogens using Testosterone Replacement Therapy. LOL like that will ever happen! These fat swine would sooner jump of a bridge then help a f**** white male use his testosterone ! SAD
    Last edited by booku; 09-12-2016 at 11:01 AM.

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    Quote Originally Posted by kelkel View Post
    That's quite a hefty dose!
    yeah on hrt that is a big dose. even on cycle 25-0.5mg eod is enough for most, but on hrt doses that would eb too much AI for most. I feel dex is stronger than stane from my exp. i also love letro also but its VERY strong so i norm rec dex

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    So which is better for a small dose aromasin or arimidex ?

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    booku is offline Associate Member
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    Quote Originally Posted by Megalodon6 View Post
    So which is better for a small dose aromasin or arimidex?
    Both are very effective for HRT at low dose twice a week(This is plenty, adex has a long half life and aromsin can render the enzyme inactive for up to 72 hrs), its all just about finding your sweet spot with bloodwork(please get the E2 sensitive, you will see ignorant people on this board think getting the regular E2 and tracking that is enough, NO that will come back with inaccurate results sometimes), and E2 seems to take a while to stabilize, which is why its tricky to dial in. But basically, to sum it up, if you are looking for ideal Mental/Brain health/Mood, I would go with arimidex , if you want something that is possibly easier on the lipids and is more potent at a smaller dose typically then aromasin would be your choice, and when I say same dose Im talking the physical pill so 1 pill or 1 mg adex = 1 pill or 25 mg aromasin
    Last edited by booku; 09-13-2016 at 07:31 AM.

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    Thanks for the knowledge bud! I take 100mgs of cypionate e3.5d then I follow up with .25mgs of arimidex 24hrs after my injections.

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