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Originally Posted by
bizzarro
You got an unfortunate combination of modest Total T levels and high SHBG ones.
SHBG is an acronym for Sex Hormone Binding Globulin. It' a liver protein released into the bloodstream that inactivates sex hormones (including T) so that no more biological action is possible.
It's the factor impacting your free T levels, which yes your right, are very very poor. Were SHBG three times less, your Free T would be twice higher. The ranges provided by your lab are ungenerous.
This condition is often treatable but sometimes not, it depends on the underlying cause for high SHBG.
These include: High estrogen levels (both endogenous and environmental), hyperthyroidism, malnutrition. Sometimes the cause might not be found, and physiological high levels are also possible. In that case, I'd recommend you to see an endo and evaluate TRT.
You seem to suffer from high body fat %. Adipose tissue has this enzyme called aromatase that converts your precious T into E2 (estradiol, the main estrogen), and I suspect it could be an important factor. Hence, it would be useful to know your E2 levels. That means you need to pull "sensitive E2" assay, if available, hopefully.
Other reduction strategies include supplementing with Vitamin D3, Zinc and fish oil.