hypothyroidism hypogonadism (BW)

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10-27-2017, 12:09 PM
assguy22

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hypothyroidism hypogonadism (BW)

Hi,

Finally I've got my lastest Bloodwork.

* 34 years old
* 1.85 / 99kg (16% bf *with caliper*)
* No roids since more than 1 year, not even supplements, no diet but working out Monday to Friday
* Levotiroxine ED 75mcgs (I had TSH=9 when I started the treatment, after 2 months with 50 TSH was 6, now I take 75mcgs)
* Low T since Jun 2016 (in the 300's in every BW).

Now Thyroid issue seems fixed with 75mcgs (or maybe doc should try with 100?), this is my last bw (23th Oct Monday).

https://s1.postimg.org/3flwq4jkkf/image.jpg

I've never had trouble with low estrogens before. WTF??!

Thank you.
10-27-2017, 12:18 PM
assguy22

I feel like shit of course. Really tired, no sex drive at all, not able to concentrate, memory loss...I don't feel like socializing or doing anything.
10-27-2017, 12:26 PM
hammerheart

Of course you need to increase to 100mcg LT4, modern guidelines recommend TSH to be <2, ideally 1-1.5 .

Not sure how much that is going to help with the low T, low E2 too is killing your well-being it seems but I guess it's from not enough T available for conversion, maybe it's time to consider TRT.

IGF-1 is very low for your age too.
10-27-2017, 02:11 PM
Youthful55guy

Are you taking an estrogen inhibitor? I'm sure you would have mentioned it, but I'll ask anyway. That's the only way I've ever had E2 lower than the detectable range.

Do you still look like that photo? If so, consider adding some fat. That might bring up the E2 conversion and help you to feel better.

Any ED problems? That commonly happens with E2 being that low.
10-27-2017, 02:54 PM
assguy22

Quote:

Originally Posted by bizzarro

Of course you need to increase to 100mcg LT4, modern guidelines recommend TSH to be <2, ideally 1-1.5 .

Not sure how much that is going to help with the low T, low E2 too is killing your well-being it seems but I guess it's from not enough T available for conversion, maybe it's time to consider TRT.

IGF-1 is very low for your age too.

I will discuss t4 dosage with my doc, I want 100mcgs too, let's see what happen.

And yes IGF-1 is very low and HGH too, and what about hyperprolactinemia? damn god, I'm fucked up and dunno why. I read about hyperprolactinemia and it's related with hypothyroidism too and it could be even a tumor in the pituitary gland but it's no that high for this I believe.
10-27-2017, 03:06 PM
assguy22

..........................................
10-27-2017, 03:14 PM
assguy22

Quote:

Originally Posted by Youthful55guy

Are you taking an estrogen inhibitor? I'm sure you would have mentioned it, but I'll ask anyway. That's the only way I've ever had E2 lower than the detectable range.

Do you still look like that photo? If so, consider adding some fat. That might bring up the E2 conversion and help you to feel better.

Any ED problems? That commonly happens with E2 being that low.

Once I finished my last cycle 1 year and 4 months ago I take no meds at all,only T4 now on an empty stomach every morning, no SERMs, no AI's, nothing.
The photo is very old. Now I'm at 16%bf, much worse, I've been dragging this hormonal situation for 1 year and 4 months now.
I have ED problems since I finished that cycle, I have no libido, I masturbate only once a week and erections are not 100% complete. It sucks.
10-27-2017, 08:16 PM
Youthful55guy

Quote:

Originally Posted by assguy22

Once I finished my last cycle 1 year and 4 months ago I take no meds at all,only T4 now on an empty stomach every morning, no SERMs, no AI's, nothing.
The photo is very old. Now I'm at 16%bf, much worse, I've been dragging this hormonal situation for 1 year and 4 months now.
I have ED problems since I finished that cycle, I have no libido, I masturbate only once a week and erections are not 100% complete. It sucks.

The Ed thing is more than likely related to low E2. It's one of the ironies of nature that men need a certain amount of E2 for normal erection. I'm at a loss though to explain why you might be so low. perhaps measurement error? probably not, but might be worth a second lab.
10-28-2017, 05:42 AM
hammerheart

Quote:

Originally Posted by assguy22

I will discuss t4 dosage with my doc, I want 100mcgs too, let's see what happen.

And yes IGF-1 is very low and HGH too, and what about hyperprolactinemia? damn god, I'm fucked up and dunno why. I read about hyperprolactinemia and it's related with hypothyroidism too and it could be even a tumor in the pituitary gland but it's no that high for this I believe.

Nay you don't have hyperprolactinemia but just a minor elevation, could easily be due to thyroid. Tumors of the pituitary cause a marked elevation in prolactin. Poor IGF-1 could have both thyroid and low E2 as factors.
10-28-2017, 12:51 PM
Youthful55guy

Quote:

Originally Posted by bizzarro

Nay you don't have hyperprolactinemia but just a minor elevation, could easily be due to thyroid. Tumors of the pituitary cause a marked elevation in prolactin. Poor IGF-1 could have both thyroid and low E2 as factors.

Really good point about the low E2 and low IGF-1 connection. I remember reading some papers a while back that linked normal E2 levels within the brain to growth hormone production. If E2 is low, GH production will be low and thus IGF-1 will be low.

I also remember my old TRT specialist (a well-respected doc in the A4M community) telling me that anastrozole decreases GH production, but I dismissed what he was saying until I read those papers and made the connection. I still use anastrozole, but at very low doses (0.5 mg per week in divided doses) and I carefully monitor my E2 levels and never let it go under 20 pg/mL.
10-29-2017, 11:34 AM
assguy22

Some people have told me that it is possible because of the inflammation/stress I am carrying out with my body. Do you think I should stop training for a month or more?

What about this supps:
Vitamin B6
Vitamin E
SAM-e
10-30-2017, 08:35 PM
ryobi1

Quote:

Originally Posted by bizzarro

Of course you need to increase to 100mcg LT4, modern guidelines recommend TSH to be <2, ideally 1-1.5 .

Not sure how much that is going to help with the low T, low E2 too is killing your well-being it seems but I guess it's from not enough T available for conversion, maybe it's time to consider TRT.

IGF-1 is very low for your age too.

yes , i agree on the TSH levels, but his Free T4 is above midrange, would be best if he pulled T# levels to see
how its converting
10-31-2017, 04:22 AM
assguy22

Thanx ryobi1

Next bw will include RT3 plus T3 Total/ T3 Free / T4 total. It's only 30€ more.
11-02-2017, 04:01 PM
assguy22

I think I may have been suffering from sleep apnea for years. I'm going to start several tests for this next week, I thought it was nightmares and that's why I woke up at night but It seems they are small cuts in my breathing. Maybe all my thyroid/low T problems come from here.