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Thread: Clomid HRT 12 month bloodwork

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    Clomid HRT 12 month bloodwork

    This month marks one year since I started doc supervised HRT with Clomid. I just had my latest bloodwork and wanted to solicit input.

    Protocol
    50mg Clomid twice a week, Monday AM and Thursday PM
    .25 to .5 mg Arimidex total per week, taken in .25 mg doses

    That's it as far as HRT goes. I take Cialis 5mg and Flowmax once a day for BPH, plus a host of OTC stuff.

    Based on the results below, I'm going to cut out the AI and see where that gets me. Doc might want to taper it off, and I would be OK with that. Everything else seems to be dialed in nicely, imho.

    Note that the PSA number is likely influenced by a weekend (and morning of bloodwork) bit of fun Mrs Cylon and I had. Listen, when you are married, you gotta strike while the iron is hot, bloodwork be damned! Will likely just retest and abstain for 48 - 72 hours prior to bloodwork being drawn. My last DRE was in July and noted no abnormalities (well, other than the doc putting his gloved finger up my butt, but it's right there in the name of the exam - Digital Rectal Examination - so what the hell should we expect??).

    Anyhow, I'm feeling good and likely will feel better dropping the AI. If we drop the AI entirely, I will retest in 90 days. If we taper, probably won't retest for 6 months or so.

    Clomid HRT 12 month bloodwork-cylon357oneyear-page1.jpg Clomid HRT 12 month bloodwork-cylon357oneyear-page2.jpg Clomid HRT 12 month bloodwork-cylon357oneyear-page3.jpg

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    Youthful55guy is online now Knowledgeable Member
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    Except for the PSA, everything looks great. Totally understand the not abstaining. When you've been married for 25 years, you take want you can get. Agree to step down E2 control. Might want to consider DIM as an alternative.
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    Quote Originally Posted by Youthful55guy View Post
    Except for the PSA, everything looks great. Totally understand the not abstaining. When you've been married for 25 years, you take want you can get. Agree to step down E2 control. Might want to consider DIM as an alternative.
    Yeah I added DIM a while back. 250mg a day then recently upped it to 500mg per day to see where that lands me.

    BTW, the last adex I took before the blood work was .25 mg 6 days before. I know the half life is around 48 hours but do not know how long before e levels would start to rise again. Any idea on that?

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    Youthful55guy is online now Knowledgeable Member
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    Quote Originally Posted by cylon357 View Post
    BTW, the last adex I took before the blood work was .25 mg 6 days before. I know the half life is around 48 hours but do not know how long before e levels would start to rise again. Any idea on that?
    It is metabolized mostly in the liver (85%), with an elimination half-life of 50 h and a terminal elimination half-life of 2 days.

    From: https://doi.org/10.1210/jcem.85.7.6676

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    Youthful55guy is online now Knowledgeable Member
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    On a different note, Can you relate your experience with Flowmax?

    In a nutshell, I have not had BPH problems until very recently. I believe it is temporary as it occurred virtually the same time as a sudden flare up of some pretty nasty hemorrhoids. Lots of inflammation in the perianal area as a result. I think that is causing the BPH. I had surgery for the hemorrhoids 2 days ago and that aggravated the BPH even more. Hopefully the inflammation will subside soon and urination will return to normal. I have a follow up visit with my GP on Monday and plan to ask her about Flowmax. Just wondering what you think of it?

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    Quote Originally Posted by Youthful55guy View Post
    On a different note, Can you relate your experience with Flowmax?

    In a nutshell, I have not had BPH problems until very recently. I believe it is temporary as it occurred virtually the same time as a sudden flare up of some pretty nasty hemorrhoids. Lots of inflammation in the perianal area as a result. I think that is causing the BPH. I had surgery for the hemorrhoids 2 days ago and that aggravated the BPH even more. Hopefully the inflammation will subside soon and urination will return to normal. I have a follow up visit with my GP on Monday and plan to ask her about Flowmax. Just wondering what you think of it?
    Ouch that surgery had to hurt!

    Flowmax is okay. It is effective in doing its job, but when you first start using it, it has some short term odd side effects. Nothing dangerous just a little weird. Reverse ejaculation is the oddest to me but it goes away after a week or two. That can be weird the first time it happens lol! Anyhow, good for urine flow and it lowers BP slightly so it's a winner in my book.

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    Oh and yeah, hemorrhoids are fun.... NOT! I take a little vitamin K2 when things get a bit.... well, no way to say this politely, bloody in that area. Way TMI maybe but I share your pain. I opted not to have the surgery though as I have just lived with them for years.

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    Youthful55guy is online now Knowledgeable Member
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    Quote Originally Posted by cylon357 View Post
    Oh and yeah, hemorrhoids are fun.... NOT! I take a little vitamin K2 when things get a bit.... well, no way to say this politely, bloody in that area. Way TMI maybe but I share your pain. I opted not to have the surgery though as I have just lived with them for years.
    I had no option, they progressed beyond grade 3 and were beginning to prolapse. Can't tell which is more painful, living with prolapsed hemorrhoids or day 2 post procedure. Hoping things get better quickly. I opted for the stapling procedure and the doc said it went well. Going to see my GP in a couple days, who has also had the procedure. Perhaps she can give me some insight into a faster recovery.


    I'm also hoping that once the swelling goes down, the urination will go back to normal, if not I plan to ask for a script for Flowmax. I've read about the retrograde ejaculation side-effect. But the way I feel now, the thought of any ejaculation is distasteful, so not a lot to lose. I can always stop once the swelling goes down.
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    Quote Originally Posted by Youthful55guy View Post
    I had no option, they progressed beyond grade 3 and were beginning to prolapse. Can't tell which is more painful, living with prolapsed hemorrhoids or day 2 post procedure. Hoping things get better quickly. I opted for the stapling procedure and the doc said it went well. Going to see my GP in a couple days, who has also had the procedure. Perhaps she can give me some insight into a faster recovery.


    I'm also hoping that once the swelling goes down, the urination will go back to normal, if not I plan to ask for a script for Flowmax. I've read about the retrograde ejaculation side-effect. But the way I feel now, the thought of any ejaculation is distasteful, so not a lot to lose. I can always stop once the swelling goes down.
    Quote Originally Posted by cylon357 View Post
    Oh and yeah, hemorrhoids are fun.... NOT! I take a little vitamin K2 when things get a bit.... well, no way to say this politely, bloody in that area. Way TMI maybe but I share your pain. I opted not to have the surgery though as I have just lived with them for years.
    This would make for a interesting yet also somewhat disturbing search history...

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    Quote Originally Posted by Youthful55guy View Post
    I had no option, they progressed beyond grade 3 and were beginning to prolapse. Can't tell which is more painful, living with prolapsed hemorrhoids or day 2 post procedure. Hoping things get better quickly. I opted for the stapling procedure and the doc said it went well. Going to see my GP in a couple days, who has also had the procedure. Perhaps she can give me some insight into a faster recovery.


    I'm also hoping that once the swelling goes down, the urination will go back to normal, if not I plan to ask for a script for Flowmax. I've read about the retrograde ejaculation side-effect. But the way I feel now, the thought of any ejaculation is distasteful, so not a lot to lose. I can always stop once the swelling goes down.
    In all seriousness, though, Flowmax has worked well for me and been no problem after the first two weeks or so. Couldn't hurt to try it if the doc thinks you need it.
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    Late update here on the PSA, but thought I would share.

    So when the doc and I reviewed the above results, we decided to try Fina again. I did a half milligram per week for six weeks, using the vodka eye dropper method. This cut my DHT almost in half but did not budge the PSA when we retested. At this time, we dropped the DHT and opted to treat for a prostate infection, using Doxycycline 100mg 2x day for two weeks. Had my follow up bloodwork (about 10 days in on the antibiotic) on Friday and got my results today. Looking much better.

    ...and now you know why I'm jealous when I see people with PSA scores of like 1.0

    Clomid HRT 12 month bloodwork-cylon357psafollowup.jpg

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    Quote Originally Posted by cylon357 View Post
    Late update here on the PSA, but thought I would share.

    So when the doc and I reviewed the above results, we decided to try Fina again. I did a half milligram per week for six weeks, using the vodka eye dropper method. This cut my DHT almost in half but did not budge the PSA when we retested. At this time, we dropped the DHT and opted to treat for a prostate infection, using Doxycycline 100mg 2x day for two weeks. Had my follow up bloodwork (about 10 days in on the antibiotic) on Friday and got my results today. Looking much better.

    ...and now you know why I'm jealous when I see people with PSA scores of like 1.0

    Click image for larger version. 

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    Very Interesting! I had a recent experience that makes me want to suggest others with PSA issues also look into the possibility of an infection rather than jumping straight to a biopsy, which can make the PSA problem even worse. I've been testing PSA annually for about 15 years and my scores are almost always in the 0.6 to 0.8 range. Then suddenly, it shot up to 8.35. About 3 weeks prior to the PSA test I also developed urination difficulty and had night sweats every night. I saw the doctor for the night sweats and had all sorts of tests, but nothing definitive. Then we did the PSA test and she started me on ciprofloxacin, flowmax and 5 mg daily of finasteride.

    The very first night, after just 1 dose of ciprofloxacin, the night sweats went away and have never returned. I stayed on the meds for 40 days and stopped both the ciprofloxacin and flowmax about 2 weeks ago with no return of symptoms. I also dropped the finasteride to 2.5 mg because testing showed my DHT went below the normal range (20 with a range of 30-85). I'll retest the DHT in a couple of weeks and decide if I need to cut back further. At that time we'll retest the PSA to see where we are at. We wanted to give the prostate time to heal after the infection before re redo the PSA.
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    .8 to 8.35?? Holy crap! I was jealous of the sub 1.0 but that 8+ would worry the hell out of me. But coming on that fast it is almost certainly an infection. Keep in mind that I am no doctor though...

    I will be interested in seeing what your next PSA score comes back at.

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    Be careful with ciprofloxacin and training. I have a partial pec tear from being on it and training (10yrs ago). I'm also on clomid but at 50mg daily and airmidex 3x a week. Test was 1159 and estogen was 70 with a 0.7 psa
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    Quote Originally Posted by Cheato View Post
    Be careful with ciprofloxacin and training. I have a partial pec tear from being on it and training (10yrs ago). I'm also on clomid but at 50mg daily and airmidex 3x a week. Test was 1159 and estogen was 70 with a 0.7 psa
    Yeah, I have had knee issues that have forced me to take it easy during the antibiotic run but they are improving.

    .7 psa... another member of the less than 1.0 club. I'm jealous! How old are you?

    Edit: Sorry, I see the cipro comment was for Y55Guy. Doxycycline was my drug, I have a BAD reaction to Levaquin and similar.
    Last edited by cylon357; 12-17-2019 at 09:29 PM.

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    46 be 47 this year. I took levaquin once and I lost 30% of my ability to smell . Those fluoroquinolones will jack you up. I will have to be on my death bed to take again.
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    Cylon357 so do you get flack from being on clomid longterm instead of injectable test? I've been using Scott Able out of Canada for physique training and he didnt understand why I didnt just inject. I like just taking a pill but wonder if injectable would give me better results.
    Last edited by Cheato; 12-18-2019 at 08:19 AM. Reason: Verbiage

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    Quote Originally Posted by Cheato View Post
    46 be 47 this year. I took levaquin once and I lost 30% of my ability to smell . Those fluoroquinolones will jack you up. I will have to be on my death bed to take again.
    My issue with Levaquin was serious cardiac problems. I went to the ER probably 5 times over the course of a few months during and right after my run in with it. Never again.

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    Quote Originally Posted by Cheato View Post
    Cylon357 so do you get flack from being on clomid longterm instead of injectable test? I've been using Scott Able out of Canada for physique training and he didnt understand why I didnt just inject. I like just taking a pill but wonder if injectable would give me better results.
    Sometimes, yeah. I think a lot of folks just aren't familiar with Clomid as HRT option or assume you are going to want to cycle.

    If the day comes that I decide to cycle, I will switch over to the needle and blast and cruise, but I am a couple of years away from being in a spot with nutrition, training and lifestyle before I feel like cycling would be appropriate. I can get numbers like yours with Clomid (Total and Free T and DHT all over range) with 50mg 3 times per week, so I'm good on my HRT for now.

    As a heads up, I have been able to basically cut my dose in half (25mg 3 times a week) and have my numbers right at the top of scale. I think you said you were taking 50mg per day, you might be able to reduce your dose and get close to the same benefits.

    Oh and do you do anything in particular for your PSA to keep it that low? I have been a member of the 2+ club for 15 years or so, would love to see something that low again (if it doesn't crash my DHT).

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    Good advise about the clomid dosage. I had cut back to 25mg per day on occasion but feel I could run less. PSA I havent done anything particular other than concentration on plant based whole foods with eggs and fish. I have been told if we all live long enough we will have some type of prostate issue.

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    Good advise
    Last edited by Cheato; 12-27-2019 at 10:01 AM. Reason: Duplicate

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    Wow I had a blond moment, im reading this saying wow thats a really low clomid dosage for a pct protocol, and thats a great test number. Im getting ready to ask whats your age and what was your hrt protocoll before you did an exit....then I realized the clomid is your hrt. Or maybe its just friday night lol, what was your total test before starting the clomid?

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    Quote Originally Posted by jamotech View Post
    Wow I had a blond moment, im reading this saying wow thats a really low clomid dosage for a pct protocol, and thats a great test number. Im getting ready to ask whats your age and what was your hrt protocoll before you did an exit....then I realized the clomid is your hrt. Or maybe its just friday night lol, what was your total test before starting the clomid?
    As low as 233 but typically around 400 on the same scale here, 250 - 1100 or whatever it is exactly

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    I am 46 and had a blood test reading of 215 and estrogen of 170. Heck I was braiding hair and watching hallmark. Urologist said let's try anstrazole 1x a week see what happens. Anstrazole dropped my estrogen to 50 and bumped my test to 500. I wanted more so he added clomid 50 mg once daily and my test went to 1159 and estrogen 100 in which I increased my anstrazole to 2-3 times a week. That's my story so far. Glad to share
    Last edited by Cheato; 01-02-2020 at 07:15 PM. Reason: Poor grammar

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