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Thread: New HRT Doc New Protocol.

  1. #1
    nickulus is offline New Member
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    New HRT Doc New Protocol.

    So I’ve been on test cyp for about a decade. Current protocol is 60mg every 3.5 days as prescribed by my internal medicine doctor. This keeps me at about 850 TT. Been feeling low energy and brain fog. My Doc told me visit a HRT specialist in my area. She ran all labs and set me up on new protocol of 85mg twice weekly. She works closely with a compounding pharmacy that will add anastrazole INTO the test cyp. Does anyone have experience with this?

    She also wants to start me on CJC/Ipamorelin 100ug twice daily 5 days on two days off. Any experience or result information from such a protocol would be greatly appreciated.

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    Quote Originally Posted by nickulus View Post
    So I’ve been on test cyp for about a decade. Current protocol is 60mg every 3.5 days as prescribed by my internal medicine doctor. This keeps me at about 850 TT. Been feeling low energy and brain fog. My Doc told me visit a HRT specialist in my area. She ran all labs and set me up on new protocol of 85mg twice weekly. She works closely with a compounding pharmacy that will add anastrazole INTO the test cyp. Does anyone have experience with this?

    She also wants to start me on CJC/Ipamorelin 100ug twice daily 5 days on two days off. Any experience or result information from such a protocol would be greatly appreciated.
    I'll second not having the anastrozole blended in with the cyp. If you have to make an anastrozole adjustment, it means you're forced to adjust your T level. That's an endless merry-go-round of adjustments.

    Where was your E2 at the old dosage with no A.I.? Where was your free T on your old dosage?
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    nickulus is offline New Member
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    Quote Originally Posted by cylon357 View Post
    CJC / Ipamorelin is a good combo. You need to know if the cjc is with or without DAC. With DAC should be dosed once or twice per week. Without DAC should be dosed daily.

    I would avoid test blended with an ai like anastozole. What if you don't need it? Better to just have it on hand separatley just in case.
    CJC is without DAC.

    E2 is at 43pg/ml without AI. She wants me around to be around 25. I’ll look at free level and let you know. I want to say it was around 450ng/dL.

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    nickulus is offline New Member
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    Quote Originally Posted by cylon357 View Post
    Good on the CJC. I've run that combo before (though once a day in the evening) and liked it.

    What is the range on E2? The one I'm familiar with tops out around 32, so 43 would be over range but not a whole lot. It will likely go up with the increase in T dose, though. Still, I wouldn't get the blend, though depending on symptoms, you may want to control E a bit. I would imagine that no more than .25 mg adex once or twice per week would do the trick. All of our bodies behave slightly differently though, and those thoughts are based on your current E2 being over range AND you having high estrogen negative sides. If either of those are not the case, then I would modify the suggestions.
    So my E2 is 43pg/ml on a scale of 11-43pg/ml.

    Free T is 194pg/ml on a scale of 33-227pg/ml

    Bio Available T is 454ng/dL on a scale of 131-682ng/dL.

    What the difference between free T and Bio available?

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    nickulus is offline New Member
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    New bloods. I'm a mess.

    Been 3 months on Test Cyp 100mg every 3.5 days mixed with .5mg anastrozole/100mg test.

    TT = >1500 ng/dL-Range 264-916
    Free T = too high to calculate- Range 33-227 pg/mL
    Estradiol = 54 pg/mL- Range 11-43
    H&H are higher range of normal
    DHT = 122-Range 12-65 ng/dL
    No SBHG tested

    Plan is to cut back to 20mg test cyp daily mixed with .1mg anastrazole adding DIIM. How much DIIM would you recommend?

    Retest in March 2021

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    If you want a real TRT program then run 80-100mg of test C per week with no AI.

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    nickulus is offline New Member
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    Respect and appreciate the response. Could you expand on the real statement? Would you consider my current protocol a low dose cycle and not TRT? Again I appreciate the feedback as I continue to learn.

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    nickulus is offline New Member
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    Quote Originally Posted by Cylon357 View Post
    I recommend 0 DIIM. You do not need it. Drop your dose to something like 125 to 150 per week.

    Your E is high because your T is high. And truth be told, your E is NOT high compared to your T.

    I'm not sure I would inject Cyp daily. Seems like a lot of sticking. Your 2x per week was probably fine, the dose is just a bit too high. But with .5mg AI 2x per week... thats just a bit too much AI for trt


    Thank you Cy!

  9. #9
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    Quote Originally Posted by nickulus View Post
    New bloods. I'm a mess.

    Been 3 months on Test Cyp 100mg every 3.5 days mixed with .5mg anastrozole/100mg test.

    TT = >1500 ng/dL-Range 264-916
    Free T = too high to calculate- Range 33-227 pg/mL
    Estradiol = 54 pg/mL- Range 11-43
    H&H are higher range of normal
    DHT = 122-Range 12-65 ng/dL
    No SBHG tested

    Plan is to cut back to 20mg test cyp daily mixed with .1mg anastrazole adding DIIM. How much DIIM would you recommend?

    Retest in March 2021

    When did you pull bloods relative to your last injection?
    Estradiol is not the correct test and is prone to reading higher in men which causes unknowing doc's (way too many of them) to then prescribe Adex when it's not necessary. You need an E2 Sensitive Assay. If your doc doesn't know this it's a big issue and should be to you. That said, if it is accurate it's still fine. A little high is always better than low and a plus for libido.
    How high are Hemo and Hema?
    DHT is high because your T is high.
    200 mgs test per week is rarely needed in TRT. Rarely. It's the root of your problems.
    You commented in post #1 about brain fog, etc. Everyone who's on TRT blames any "off" feeling on testosterone . How do you know something else wasn't causing you issues?
    You said your doctor works closely with a compounding pharmacy. This is ONLY because it amplifies her profits.
    There is zero need to ever mix adex with your testosterone. The guys above are 100% correct.

    My advice would be to drop back to your original dose of 120 or so split twice weekly and totally drop the adex. It's rarely needed if your protocol is dialed in. Stick with it for a few months and retest. Also remember total T doesn't matter, only Free T. Free T is what works for you.

    When it comes to your possible new protocol of daily injections. Nothing wrong with it but what a pain in the ass. I know, it only takes a few minutes but seriously who wants to do that every single day? Then if you travel you have to drag all that crap with you. Not fun, not needed and not worth the hassle imho. And again, you should not need any adex.

    You're not a mess. Just bouncing around protocols is never prudent and having a doc that may not be quite as sharp as he/she thinks may be another issue...
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  10. #10
    nickulus is offline New Member
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    Quote Originally Posted by kelkel View Post
    When did you pull bloods relative to your last injection?
    Estradiol is not the correct test and is prone to reading higher in men which causes unknowing doc's (way too many of them) to then prescribe Adex when it's not necessary. You need an E2 Sensitive Assay. If your doc doesn't know this it's a big issue and should be to you. That said, if it is accurate it's still fine. A little high is always better than low and a plus for libido.
    How high are Hemo and Hema?
    DHT is high because your T is high.
    200 mgs test per week is rarely needed in TRT. Rarely. It's the root of your problems.
    You commented in post #1 about brain fog, etc. Everyone who's on TRT blames any "off" feeling on testosterone . How do you know something else wasn't causing you issues?
    You said your doctor works closely with a compounding pharmacy. This is ONLY because it amplifies her profits.
    There is zero need to ever mix adex with your testosterone. The guys above are 100% correct.

    My advice would be to drop back to your original dose of 120 or so split twice weekly and totally drop the adex. It's rarely needed if your protocol is dialed in. Stick with it for a few months and retest. Also remember total T doesn't matter, only Free T. Free T is what works for you.

    When it comes to your possible new protocol of daily injections. Nothing wrong with it but what a pain in the ass. I know, it only takes a few minutes but seriously who wants to do that every single day? Then if you travel you have to drag all that crap with you. Not fun, not needed and not worth the hassle imho. And again, you should not need any adex.

    You're not a mess. Just bouncing around protocols is never prudent and having a doc that may not be quite as sharp as he/she thinks may be another issue...
    Thank you so much for your time and the information Kel! Huge amounts of respect.

  11. #11
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by nickulus View Post
    Thank you so much for your time and the information Kel! Huge amounts of respect.
    Glad to help brother! Update this thread with how things go please.
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