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Thread: Starting TRT - Need Advice

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    amindzeye's Avatar
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    Starting TRT - Need Advice

    Hi all, I'm 33 5'6", 156lbs. I am going to be starting TRT at 100mg Test Cyp/ Week, Kisspeptin-10, cjc1295/Ipamorelin-6mg/12mg, Exemestane 25mg. My question is, the clinic I am dealing with first suggested anastrazole at .5mg/2x week. I had them switch to exemestane. They are not familiar with the dosage of it. I am wondering what should I dose at? I have not started TRT yet.

    Here is my blood work:

    Test Serum - 580 ng/dl (264-916)
    SHBG - 43.9 nmol/l (16.5-55.9)
    Test Free Calc - 100.8 pg/ml (42.3-190)
    TSH - 1.940 uIU/ml (.45 - 4.5)
    T3 - 2.6 pg/ml (2.0-4.4)
    T4 - 1.26 ng/dl (.82-1.77)
    Cortisol - 15.4
    LH - 5.1 mIU/ml (1.7-8.6)
    FSH - 8.8 mIU/ml (1.5-12.4)
    Estradiol - 13.8 pg/ml (7.6-42.6)
    Hemoglobin - 13.4 g/dl (13-17.7)
    Hematocrit - 40.8% (37.5-51)
    Last edited by amindzeye; 06-15-2021 at 04:14 PM.

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    Quote Originally Posted by Cylon357 View Post
    I'm not going to lie: with your numbers, I would not be starting TRT. The peptides, yeah but Test and an AI, no. You have good numbers, man. A lot of men on TRT would be delighted to see those.

    If you want to cycle or are a professional athlete, then by all means, needle up! But otherwise, no, I would not start TRT.

    I might add liquid boron at 5-10 mg per day to bring down the SHBG some, thus freeing up both DHT and Testosterone. BTW, it would be nice to see DHT and PSA... you are a little young to be thinking about prostate issues too much, but it never hurts to be on top of things. DHT is an important male hormone, it is always good to pull it with Test.
    Thanks for the reply. You have me second guessing this now. The problem is, I already purchased the therapy kit. I would only have enough for a 200mg, 10 week cycle. Surely this isn't enough for a proper cycle. I don't know where to get extra test, or proper pct meds. I would only have aromasin on hand. Unless the kisspeptin-10 would prevent the need for pct meds?

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    Everything Cylon said above. Save your items for later. They'll last years.
    Zero reason for Kisspeptin. It's an LH stimulant which will not work when the hypothalamus / pituitary goes into suppression from exogenous testosterone . If something like this were effective then there'd never be a need for PCT. Serms like Clomid and Nolva would be worth their weight in gold at that point.
    Keep reading and learning.
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    Quote Originally Posted by kelkel View Post
    Zero reason for Kisspeptin. It's an LH stimulant which will not work when the hypothalamus / pituitary goes into suppression from exogenous testosterone.
    From what I was told, the kisspeptin acts as an alternative to HCG during cycle. You're saying that it is pointless to use this during cycle then? If it is, then it would be more beneficial to use it along side cjc1295/ipamorelin without the administration of exogenous testosterone ?


    EDIT: Upon further reading I see the point of HCG is to tell the pituitary gland to produce LH and FSH. So I take it since HCG is the favored med to be administered during a cycle, this means the pituitary gland is more likely to be shut down and not the hypothalamus? Since Kisspeptin-10 tells the hypothalamus to send GnRH to the pituitary gland, it's already telling something that is not off(hypothalamus) to turn on. Rendering the administraion of kisspeptin pointless?
    Last edited by amindzeye; 06-17-2021 at 01:12 AM.

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    Based on all the different guys' blood work you two have analyzed over the years. Is there any kind of signs in blood work that can predict if ones HPTA will not recover from exogenous hormones?

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    Quote Originally Posted by Cylon357 View Post
    The part in bold is not right. HCG imitates LH and to a lesser degree FSH, it does not cause their release.
    Yeah, I found austinites hcg article after I edited that post, and realized I didn't fully grasp it when I wrote that. I have seen reports of guys growing their testicles back with taking kisspeptin instead of hcg, during exogenous administration. How is this possible?

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    If kisspeptin can be used to grow the testicles back via stimulation or imitation of GnRH, wouldn't this suggest that it's the hypothalamus that is shut down, and not the pituitary gland?

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    Quote Originally Posted by Cylon357 View Post
    Good questions, but outside my knowledge. You could always test it on yourself and find out... that is what a lot of us do with various molecules.
    Looks like that's what I'm going to do. I just have to wait till I get pcts and another vial of Test.
    If my cycle looked like this:

    10 week cycle
    Test Cyp 400mg/week via one injection
    Kisspeptin
    dbol - 20mg/ 5 days a week for pre-workout
    Exemestane on hand, not administered until symptoms of high estrogen 25mg
    cjc1295/Ipamorelin

    PCT
    Clomid - 50/50/25/25
    Nolva - 20/20/10/10

    Does this look good? Would 400mg for ten weeks be more beneficial than 300mg for 12 weeks? How much exemestane is typically needed for these dosages of Test, if symptoms were to show? My bodyfat% is around 17-20.

    Supplements would include :
    Creatine
    Protein
    Vitamin C&D
    Fishoil
    AAKG
    L-carnitine/L-tartrate
    Fortify Joint Supplement
    TTA
    Last edited by amindzeye; 06-17-2021 at 04:50 PM.

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    Quote Originally Posted by Cylon357 View Post
    BTW, it would be nice to see DHT and PSA....
    I have a full lipid panel, complete metabolic panel, and some other things tested, here is what I think you asked for.

    Prostate-Specific Ag, Serum - .8 ng/dl (0.0-4.0)
    IGF-1 - 195 ng/ml (95-290)

    I didn't have DHT tested, but DHEA. I don't know if this is relevant
    DHEA - 253 ug/dl (138.5-475.2)

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    Quote Originally Posted by Cylon357 View Post
    Dbol in a first cycle CAN be OK IF you have done your homework. Personally, I would leave it out. Why is it in your plan? Ask that question of every compound.
    Your body fat is a little high to be cycling. Yes, it can be done but you run the increased risk of sides.
    I'm going to drop the dbol as it introduces extra variables into the equation. I figured my bf% was a little too high. I am going to start with the cjc1295/ipamorelin, right away. Alongside TTA, and if I decide to get chromium picolinate. I should drop 6-8 lbs of fat within the next month. This will give time to source what's still needed, and by then I should be around 14-16 percent bf. Which if I'm not mistaken is the high end of what's acceptable to start a cycle.

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    Thanks for your advice and suggestions.

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