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  1. #1
    Turkish Juicer's Avatar
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    Single dose of triptorelin gets bodybuilder’s hormones going again

    Italian endocrinologists managed to restore the natural testosterone production of a bodybuilder whose sex hormone production had shut down after 13 years of taking steroids. All they had to do was give the 34-year-old man a single dose of 100 micrograms triptorelin. An article by the researchers, who work at the University of Brescia, was published recently in Fertility & Sterility.

    The bodybuilder went to a doctor in September 2008 because he was depressed, had no energy and had lost all interest in sex. He told the doctor he’d been using steroids since he was 21.

    The guy took 10-week courses. Typically he would inject a daily 25 mg nandrolone and 25 mg stanozolol for the first 8 weeks, and follow it with 2 weeks of 50 mg mesterolone daily [say: primo]. The following week he would take 50 mg clomid daily, and for the last week he’d inject himself three times with 2000 IE hCG .

    Well, that’s what the doctors reported. Probably the man took hCG first and clomid after. What’s more the doses sound very responsible to us. If bodybuilders tell doctors how much steroids they’ve been using, in our experience you need to triple the doses.

    How many courses the man took each year is also not mentioned in the article.

    The bodybuilder did jack up his doses from 2005 to 2008. During the 8 weeks that he injected stanozolol and nandrolone, he also started to use boldenone , injecting an average of 50 mg per day for a period of 3 weeks. And that’s where it went wrong, according to the blood tests. The doctors examined the guy in September, but decided to just observe for a few months. A damaged axis often just needs time to recover. But when the doctors examined the bodybuilder’s blood again in January 2009, there had been hardly any improvement.

    The doctors decided to treat the guy with the GnRH analogue triptorelin. GnRH is a hormone that consists of only 10 amino acids. It is produced in the brain by the hypothalamus and stimulates the production of FSH and LH by the pituitary gland. The hormones travel in the blood to the sex glands, where they get these to produce testosterone .

    The bodybuilder responded immediately to the hormone treatment. Within several minutes the concentration of LH and FSH in his blood had risen.

    The doctors saw the bodybuilder 10 days later. His energy had returned and the testosterone concentration in his blood had risen to 7 ng/ml. Another three weeks later, his testosterone level was still normal, and his libido had returned too.

    Source: Fertil Steril. 2010 Apr 21.

  2. #2
    flatscat's Avatar
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    VERY interesting.

  3. #3
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    Seems to good to be true.

  4. #4
    bbcrazy is offline New Member
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    I just did a 4 month cycle of 250 sus one ml a wk and 1ml eod of prop and masteron . I did 250iu of hcg every 4 days the whole way through. The last 2 weeks after last shot of sus i did proviron 25mg daily. I also stoped prp and masteron a week befor my last shot of sus. After last shot of sus and proviron for 14 days I did one shot of triptorelin 100mcg. My labido never droped it was crazy I felt like I never came off. I didint loose one pound after a 4 month cycle. Its only bin a month now but still I have to say I am happy with it so far

  5. #5
    Pete75 is offline New Member
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    Very interesting....

  6. #6
    BJJ's Avatar
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    I had no idea, I will check it out.

  7. #7
    BJJ's Avatar
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    Can you post the link for the study?

  8. #8
    nunyabizness is offline Junior Member
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    I'm curious as to whether or not this would work in older men who have naturally decreased T, or if only in people who messed up their systems with steroids . ie - Does there have to be a potential for full function in order for this drug to work, and do men who are hypogonadal due to age have full function if something like this is used?

  9. #9
    bigbossofdariver is offline Junior Member
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    why would a man that was cycling for 13 yrs just completely go off everything?

  10. #10
    rebelstate is offline Junior Member
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    TriptorelinFrom Wikipedia, the free encyclopediaJump to: navigation, search
    Triptorelin
    Systematic (IUPAC) name
    5-oxo-D-prolyl-L-histidyl-Ltryptophyl-L-seryl-Ltyrosyl-3-(1H-indol-2-yl)-L-alanylleucyl-L-arginyl-L-prolylglycinamide
    Identifiers
    CAS number 57773-63-4
    ATC code L02AE04
    ChemSpider 13835459
    Chemical data
    Formula C64H82N18O13
    Mol. mass 1311.5 g/mol
    SMILES eMolecules & PubChem
    Pharmacokinetic data
    Excretion Renal
    Therapeutic considerations
    Pregnancy cat. D
    Legal status ℞-only
    Routes Implant

    Triptorelin (acetate or pamoate), a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). In the United States, it is sold by Watson as Trelstar.

    During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels ), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. In contrast, gonadotropin-releasing hormone antagonists do not cause a surge, but a sudden reduction of testosterone levels.
    Systematic IUPAC Name: [d-Trp6]GnRH

  11. #11
    rebelstate is offline Junior Member
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    note the last paragraph of my previos post....During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels ), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. In contrast, gonadotropin-releasing hormone antagonists do not cause a surge, but a sudden reduction of testosterone levels.
    Systematic IUPAC Name: [d-Trp6]GnRH

  12. #12
    dosXX's Avatar
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    Quote Originally Posted by BJJ View Post
    Can you post the link for the study?
    ^^^^^^^^
    x2

  13. #13
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    Quote Originally Posted by BJJ View Post
    Can you post the link for the study?
    http://www.ergo-log.com/triptorelin.html

    Quote Originally Posted by rebelstate View Post
    note the last paragraph of my previos post....During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels ), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. In contrast, gonadotropin-releasing hormone antagonists do not cause a surge, but a sudden reduction of testosterone levels.
    Systematic IUPAC Name: [d-Trp6]GnRH
    Of note to the wikipedia information, they are giving these people MUCH higher doses of Triptorelin(in the MG range) and that is the cause of the surge and crash. People using this as a PCT are using a single shot of 100mcg. So far I'm reading of 2 people currently using it and are on there fourth week after their shot of Triptorelin and still feel great.

    To further add to the difference in dosage for someone using this for PCT(single 100mcg shot) and someone using it for prostate cancer... http://www.drugs.com/dosage/triptorelin.html

    "For the palliative treatment of advanced prostate cancer. Administered as a single intramuscular injection in either buttock. Due to different release characteristics, the dosage strengths are not additive and must be selected based upon the desired dosing schedule.
    3.75 mg by intramuscular injection every 4 weeks
    or
    11.25 mg by intramuscular injection every 12 weeks
    or
    22.5 mg by intramuscular injection every 24 weeks"
    Last edited by dece870717; 03-10-2011 at 08:02 PM. Reason: Adding to..

  14. #14
    BJJ's Avatar
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    ^^^
    Thank you mate.

  15. #15
    HDH's Avatar
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    but I've read articles about it .... I'm Italian
    and serves to suppress testosterone levels !

  16. #16
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    The product should be used only under supervision of a specialist who has equipment available for regular monitoring of therapeutic response. It 'important that the injection of sustained-release preparation is carried out in strict accordance with the instructions in 6.6, â € œIstruzioni for the use and manipolazioneâ €?. The suspension should be injected immediately after reconstitution.
    Dosage and method of administration of a dose syringe, equivalent to 3.75 mg triptorelin, should be administered subcutaneously every 28 days (eg in the skin of the abdomen, the buttock or nearby) or by deep intramuscular injection .
    The injection site must be changed each time. Men: injection with a syringe, equivalent to 3.75 mg triptorelin, once every four weeks. For a continuous suppression of testosterone levels , it is important that the administration takes place every 4 weeks. In the female: endometriosis and uterine myomas injection with a syringe, equivalent to 3.75 mg triptorelin, once every four weeks. Treatment should be initiated in the first 5 days of the cycle.
    In children: Early treatment of an injection syringe, equivalent to 3.75 mg triptorelin, on days 0, 14 and 28.
    Thereafter one injection every 4 weeks.
    If the clinical effect is insufficient, the injection every three weeks. The dose should be based on body weight.
    Children weighing less than 20 kg should receive a dose of 1.875 mg (half dose), children between 20 and 30 kg of body weight will receive a dose of 2.5 mg (two thirds of the dose), children weighing more than 30 kg will receive a dose of 3.75 mg of triptorelin (full dose).
    Note to particular groups of patients: - In the elderly do not need a dose adjustment. - According to available data, it is necessary to reduce the dosage or prolongation of the dosing interval in patients with impaired renal function. Duration of treatment of prostate cancer treatment Gonapeptyl Depot is usually a long-term therapy.
    Endometriosis and uterine myomas The duration of treatment depends on the initial severity of endometriosis, changes in its clinical manifestations (functional and anatomical) and the evolution of the volume of uterine myomas, determined by ultrasonography during the treatment. Normally, the maximum possible result is achieved after 3 or 4 injections. In view of the possible effect on bone density, treatment should not be longer than 6 months (see section 4.4). Central precocious puberty (CPP) The treatment should be stopped once it reaches a bone maturation over 12 years in girls and 13 years in males.

  17. #17
    HDH's Avatar
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    tradotto con google traslate

  18. #18
    dece870717's Avatar
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    Quote Originally Posted by HDH View Post
    but I've read articles about it .... I'm Italian
    and serves to suppress testosterone levels!
    Did you read my post? Its given in dosages that are 37.5 times the dosage people are using it for their PCT. It's a huge difference!

  19. #19
    warchild's Avatar
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    where can i get some?

  20. #20
    trix8 is offline Associate Member
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    extremepeptide.com thiers guys who have been on 2plus years at proffesional muscle.com with no hcg making logs saying they had no lack of sex drive during pct...it was better then on he said he could only compare it to puberty Dont have the link but two people both took the shot about 4 weeks ago and took last shot of test about 7 weeks ago. So the longest the best story i heard was the guy on for 2 plus years and now has taken the triporelin shot about 5 weeks ago and says he feels great better then on

  21. #21
    dosXX's Avatar
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    thanks for posting those links

  22. #22
    HDH's Avatar
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    suppression in that range will total no....

  23. #23
    HDH's Avatar
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    is used for chemical castration

  24. #24
    zaggahamma's Avatar
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    Quote Originally Posted by HDH View Post
    is used for chemical castration
    what is used for chemical castration?

  25. #25
    HDH's Avatar
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    I read that initially have up to testosterone but within four weeks is completely eliminated the production of LH and FSH and lasts for some time
    this is used for prostate surgery, and to block ovulation in the woman in the case of surgical operations to remove tumors ...

  26. #26
    BJJ's Avatar
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    what a confusion...

  27. #27
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    Quote Originally Posted by HDH View Post
    suppression in that range will total no....
    Ur an idiot, its used to castrate males yes, at superphysiological doses.

  28. #28
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    Used too high, this shit will shut you down so hard you may aswell be castrated.

    I'm running 50mcg in single shot at the start of my next PCT with BW done.

  29. #29
    BJJ's Avatar
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    ^^^
    Thanks for showing up.

    I am also considering to try it since this fourth cycle will be 20 weeks long ...

  30. #30
    Bulkn's Avatar
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    Swifto or anyone end up trying this?

  31. #31
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    Bump!!!

  32. #32
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    bumping because i'm going to order a bottle and run at the start of pct here in a few.

  33. #33
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    Let us know how this works kmms! I had a conversation about a week ago with Dr. Scally and he should be including it in a new research paper on pct that he will be putting out in the near future.

  34. #34
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    Definite bump. This is really interesting and I'd love to hear more experiences

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