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Thread: hCG and Pregnenolone; What you should know.

  1. #161
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    Quote Originally Posted by 2Sox View Post
    Please let us know how this works out.
    Dr. John Crisler and I just spoke to this, while 3 injections a week will work he likes a small daily injection as it mimics a more natural hormonal state...I agree.

  2. #162
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    Quote Originally Posted by Moparman View Post
    I do 250iu 3x a week
    And this is totally fine as well...pretty close to perfect to be honest.

    It works for me...

  3. #163
    TeresaDavis is offline New Member
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    that waz quite a informative piece of article nice written too.

  4. #164
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    Quite a different take on the subject over there.

  5. #165
    schon is offline New Member
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    Looks like I'll have to be extra vigilant in regards to my E2 levels.

  6. #166
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    At low doses like 100 iu a day or even 250 EOD should not impact E2 in most men. I have had numerous discussions with my Physician on just this subject and he said he rarely sees any issues with these low daily doses...and he sees 1000's of men in his care.

    That said, we all should be monitoring E2 on any type of HRT...that's just a good protocol practice for everyone.

  7. #167
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    Would you recommend HCG if you have had or intend to have a vasectomy, I would assume yes but I'm just wondering what your opinion was

  8. #168
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    Quote Originally Posted by tlow2013 View Post
    Would you recommend HCG if you have had or intend to have a vasectomy, I would assume yes but I'm just wondering what your opinion was
    Yes, some Physician's consider HCG a neurohormone and that it acts on LH receptors in the brain. It provides for a great sense of well being and some claim an enhanced lift in libido.

    Dr. Crilser prescribes it for his men who are Primary Hypogonadal.

  9. #169
    ImpeccableChaos is offline Junior Member
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    I posted a new thread before I read this, sorry i am new. But to be clear, even after 5-6 years of TRT is it still good to start hcg therapy, and will it bring them back to size and even get some production? I am on twice a week T injections (1mil total) and am 55yrs old.

  10. #170
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    Quote Originally Posted by ImpeccableChaos View Post
    I posted a new thread before I read this, sorry i am new. But to be clear, even after 5-6 years of TRT is it still good to start hcg therapy, and will it bring them back to size and even get some production? I am on twice a week T injections (1mil total) and am 55yrs old.
    Yes, even with that amount of time you can start. It will take some time for the receptors to upregulate...but they will.

  11. #171
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    I have moved the posts from this sticky to get it back on track... carry on...
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  12. #172
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    Quote Originally Posted by Script View Post
    GDevine, will the administration of HCG during TRT raise LH and FSH levels and subsequently show up in labs? Or does hcg "mimic" LH and therefore doesn't show up in labs?
    According to the drug insert for Ovidac, the hCG manufactured by Cadila Healthcare Limited, Ahmedabad, India:

    "About 10%-20% of a therapeutic dose of hCG is excreted in the urine within 24 hours; detectable amounts [bold italic letters are mine] of the drug may be detected in the urine up to 3-4 days."
    Last edited by 2Sox; 04-06-2013 at 09:25 AM.

  13. #173
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    Thanks for keeping this thread alive

  14. #174
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    Long story short. I have trouble taking Testosterone injections. It makes me feel worse. So now I am about to start HCG only for my testosterone. I might add Test C later and see if the combo actually works for me. My question is, How much is a good dose. My Dr wants me to take 1000iu x 3 per week. I think this might be a fertility dose. Is it? Should I try this at first and then tapper down?

    Just to give you an idea of how my body reacts to Test C. When I took 100mg per week my total T levels were around 900-1000. I had high e2 conversion. E2 got up to 60 before the Dr I was seeing at the time gave me ai.


    Also, my LH is really low. Last 2 test were 1.4 and 1.7


    Thanks
    C
    Last edited by cah027; 04-28-2013 at 08:17 PM.

  15. #175
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    @ Script. HCG will not raise LH on a blood test.

    @ cah027. A fertility dosage is much more. 5-10K actually. Have you tried gels? Androgel 1.62% maybe?
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  16. #176
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    Quote Originally Posted by kelkel View Post
    @ Script. HCG will not raise LH on a blood test.

    @ cah027. A fertility dosage is much more. 5-10K actually. Have you tried gels? Androgel 1.62% maybe?

    Never tried the gel. Too expensive cause my Ins won't cover it. Also, my dad has the same issues with Test C and he was on androgel and had the same issues. Must be an inherited issue with this stuff or our E2 levels were never optimal or polycythemia.

    Also my Dr wants to put me on HGH but I can't afford $900 or more per month.. I got a messed up pituitary for sure but no tumor.

  17. #177
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    Ok...my Doctor prescribed me TRT, but nearly keeled over when I learned the cost of those patches.
    I haven't started yet because of the cost, but after my last cycle (Test e only, 3 mo ago) I feel lethargic again, low libido, that much more difficult to keep weight off, not adding lean- perhaps even some loss. My trainer thinks he can get my test levels up naturally, but we'll see at the next blood test.
    My question is, which also concerned me is, once on TRT it's for life right? Is TRT enough to permanently shut the twins down? Cause as I read this post hCG will keep the tests active even when on TRT for years, yes?

  18. #178
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    thanks for this thread GD, helped me a lot

  19. #179
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    gdevine ;

    hello I'm 49yo and have been on trt IM for 6 weeks my hcg came in a vial and was like a paste stuck to the vial not a powder is this normal and ed is still a problem I pin 1.5 ml/week .5mg anastrozole/wk day after pining 10mg tamox on day four after pin and 1000u of hcg the day after pin please HELP ed is got me worried no improvments after 6 wks of trt???

  20. #180
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    Quote Originally Posted by chagger64 View Post
    gdevine ;

    hello I'm 49yo and have been on trt IM for 6 weeks my hcg came in a vial and was like a paste stuck to the vial not a powder is this normal and ed is still a problem I pin 1.5 ml/week .5mg anastrozole/wk day after pining 10mg tamox on day four after pin and 1000u of hcg the day after pin please HELP ed is got me worried no improvments after 6 wks of trt???
    Start a new thread. This is a sticky and not for the purposes you are using it for here.

    I and others will be happy to help.

    You're new, read the member rules in the stickies as well.

    gd

  21. #181
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    Quote:

    [Pregnenolone is a hormone that many Doctors and men are not familiar with or understand it's role in the CHOL pathways but it's critically important to our health as it is a "precursor hormone" to all other hormones. Restoring Pregnenolone to optimal levels is important but seems to get the least attention by Doctors. Remember, the testes are the single largest producer of the hormone Pregnenolone. Pregnenolone is important for proper mental functioning and is the precursor to all of the steroid hormones found in the three CHOL pathways such as DHEA, testosterone , DHT, estrogen, cortisol...

    So what are the benefits of Pregnenolone?

    In our bodies Pregnenolone is manufactured by cholesterol (CHOL). The hormone performs many functions in a mans body, including:

    1. Promotes healthy brain function and protects against dementia and Alzheimer's disease. Many men state feeling good when they start supplementing Pregnenolone.
    2. It can also prevent age related diseases and support the Central Nervous System (CNS).
    3. Boosts the immune system and increases energy produciton.
    4. Protects against coronary disease and improves heart health and can lower cholesterol levels.
    5. Enhances mood and relieves depression. Many men state their mood betters when they start supplementation.
    6. Relieves arthritis pain!
    7. Fights the effects of fatigue and stress.

    The optimal serum levels for Pregnenolone is 180 ng/dl for men. Pregnenolone can be purchased over the counter in a pill (micronized is the best for pills) or sublingual form in addition to transdermal creams. A typical dose is 50 to 200 mg daily best taken in the morning on an empty stomach (cream applied in the morning as well). Pregnenolone is considered safe and because is converts to DHEA which leads to other hormones it's best to get your Pregnenolone levels tested before supplementing.]

    Besides hCG you mention "pregnenolone," an over the counter supplement. A google search brings up very little useful information on this, compared to other supplements discussed on this forum. Can you expound on some more info on the use and benefits on supplementing pregnenolone when on TRT, please. Is that something you take on a regular basis? What do you look for to adjust your dosage?
    I can find the medical terms, but it'll be great to learn how it helps someone like you or me from those like yourself who's benefitted from it. Thanks.

  22. #182
    TB90 is offline New Member
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    Wow I've only been a member for a day.. I've been on trt for years and did not know all of this information about hcg ..

  23. #183
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    nice thread keep it up

  24. #184
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    newb looking for advice here....

    on 200mg test cyp every 10 days...and just started with hcg . MD wants me to take 500iu 4 days before my test inj, and two days before my test inj......obviously thats 1000iu / every ten days.... thing is he also informed me that my script has extra, and that i can take a 3rd injection during that time of hcg, just that he wants me to go with 2 or 3 and stick with it till we do blood. ANyone have thoughts or reasons to do 2 or 3? yes ive read alot of posts here ,still not sure, i rather side on less is best if its doing the job.

    thanks

  25. #185
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    newb looking for advice here....

    on 200mg test cyp every 10 days...and just started with hcg . MD wants me to take 500iu 4 days before my test inj, and two days before my test inj......obviously thats 1000iu / every ten days.... thing is he also informed me that my script has extra, and that i can take a 3rd injection during that time of hcg, just that he wants me to go with 2 or 3 and stick with it till we do blood. ANyone have thoughts or reasons to do 2 or 3? yes ive read alot of posts here ,still not sure, i rather side on less is best if its doing the job.

    thanks

  26. #186
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    Quote Originally Posted by sfgiantsfan55
    newb looking for advice here....

    on 200mg test cyp every 10 days...and just started with hcg . MD wants me to take 500iu 4 days before my test inj, and two days before my test inj......obviously thats 1000iu / every ten days.... thing is he also informed me that my script has extra, and that i can take a 3rd injection during that time of hcg, just that he wants me to go with 2 or 3 and stick with it till we do blood. ANyone have thoughts or reasons to do 2 or 3? yes ive read alot of posts here ,still not sure, i rather side on less is best if its doing the job.

    thanks
    Might get more help if you start your own thread

  27. #187
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    yes i agree but...... i have less than 50 posts and therefore cant start my own thread just yet.

  28. #188
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    Omg, love the info... but crap I need a dictionary :-\

    Sure hope my doc is familiar with all this, guess I'll find out. Going to go ahead and print it out. If I tried to explain this he'd think I was smoking crack. Thx for the info!!

  29. #189
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    Does HCG have to be sc. injection or can I go IM?

  30. #190
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    Great read, thanks.

  31. #191
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    Quote Originally Posted by ecdysone View Post
    Totally agree!
    --Despite the often stated fact that very high doses of HCG will down-regulate its target tissues, a couple studies show this does not occur even with doses >5000 IU/week for long periods of time. However, it's unlikely the body can do much with such high doses [with the exception of fertility therapy] so it's a waste of hormone.
    Can you provide a link to that study debunking Leydig receptor insensitivity?

  32. #192
    sambrown is offline New Member
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    This post is very informative.

  33. #193
    Cam2012 is offline New Member
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    Great read. Thanks

  34. #194
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    any recommendation on which brand of DHEA and Pregnenolone to use?

  35. #195
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    Any "micronized" product will work. I use MRM brand personally. Cheap and effective.
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  36. #196
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    thanks kel. i was actually going to order that brand from bb.com, but it said they couldn't ship dhea to my state.

  37. #197
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    Amazon has it. All MRM DHEA and Preg is Micronized.
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  38. #198
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    found them on amazon with free shipping after i read your post. thanks brotha!

  39. #199
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    Just received my dhea and it does not say micronized anywhere on the bottle, but it did in the description..what gives? Kel does yours look the same?
    Attached Thumbnails Attached Thumbnails hCG and Pregnenolone; What you should know.-image.jpg  

  40. #200
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    It's correct and had me worried as well. I actually called the company when I saw that months ago and spoke to two different people on different days. All their products are micronized and upon their next production they are going back to labels that say micronized. I verified it with different sources. No worries.
    Last edited by kelkel; 08-28-2014 at 06:23 PM.
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