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Thread: hCG and Pregnenolone; What you should know.

  1. #201
    Chauffeur is offline Associate Member
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    Kelkel, the study posted at the beginning of this thread shows that men on TRT responded well to 500iu of hCG EOD. Why is it that many posters feel that this number is too high?

    Many seem to be seeing good results on 250iu EOD or even twice weekly.

    According to that study, there was no significant increase in E2, but many forum posts I've read seem to caution against a dose that high due to E2 issues.

    What has your experience been?

    Thanks!

  2. #202
    MisterD is offline Junior Member
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    Hey guys

    Ive been on TRT for over a 1.5 years and my protocol never had hcg in it...

    Im probably going to look in to having a baby next year so what do you guys think, am i screwed? Or do you think i can reproduce again?

    I was thinking should i stop the TRT for 2 weeks and start my HCG like if i was on a cycle to let my body jump start or just keep on with my TRT and add the HCG?

    Thanks

  3. #203
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Hall of Famer ~ No Source Checks
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    No, not screwed. Just get hcg in your protocol asap.
    Stay on TRT and simply add hcg in.
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  4. #204
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    I second what Kel says. Each individual is different but there have been reports of many men on this forum who have been off hCG longer than you and have had the success your looking for.

  5. #205
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  6. #206
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    Quote Originally Posted by Chauffeur View Post
    Kelkel, the study posted at the beginning of this thread shows that men on TRT responded well to 500iu of hCG EOD. Why is it that many posters feel that this number is too high?

    Many seem to be seeing good results on 250iu EOD or even twice weekly.

    According to that study, there was no significant increase in E2, but many forum posts I've read seem to caution against a dose that high due to E2 issues.

    What has your experience been?

    Thanks!
    I think because it's higher than most take. When I see the word "significant" I'm suspicious as to what exactly that means. The same raise of E2 in one individual can be very significant, while in another it won't be at all. 500iu EOD averages out to 1750iu/week - over a two week period. That's a substantial amount - which in my opinion will definitely impact E2 levels.

    I take 125iu/day - does the job just fine - and I take 12.5mg Aromasin every six days to keep E2 stable on that amount.

  7. #207
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    This is something I've always tried to stress, it's not simply just about testosterone when you get shut down - or when people go on TRT - because even with TRT - you aren't replacing other vital hormones LIKE Pregnenolone & DHEA, not to mention other hormones that are formed through the same pathways coming FROM And TO gonadotropic nerve pathways - such as oxytocin, vasopressin etc......I think when things aren't working normally; or naturally, there is a whole lot of things that people are missing out on....The optimal situation is of course, keeping your natural test production going, and in an optimal ratio with all other hormones.....unless ofc you have a testicular injury that is expected to last ; then TRT may be prudent if you ever want some degree of quality of life and vitality......

    To be clear, I'm not against folks who are on TRT - and there may very well be other reasons - but at least supplement with the other neurosteroids AS WELL....and at some point you may find some other solution besides TRT...again, TOTALLY UP TO THE PERSON IN QUESTION.

    Other interesting compounds similar to or re-booting natural test production would be....
    -Opiate antagonists; naltrexone
    -D-Aspartic Acid/NMDA
    -WAY 100,635 (very very hard to obtain, unless you have/know a lab or can get from sigma)
    -Isolated amentoflavone
    -Forskolin

  8. #208
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    HGH4Lymes is offline New Member
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    thanks for the great read. i've read the same recommendation several times on the site too.
    my doc automatically started me on HCG and anastrolozle w/ my test treatment. this is good piece of mind knowing i have a knowledgeable doc. they say never have blind faith in an accountant, doctor or lawyer or you'll end up broke, sick and in jail

  9. #209
    MisterD is offline Junior Member
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    Guys,

    Im changing my protocol to Sub Q
    50mgs on Monday and 50mgs on Thurs of Test.
    I know that 100ius of HCP ED is best but if i wanted to do EOD or 3 times a week would I be doing 250ius of HCG on Sunday, Wed and Friday or just do EOD and what ever day its lands?

  10. #210
    kelkel's Avatar
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    Your preference is all that matter. There's nothing saying daily is better, just some prefer it. I go M-W-F @250 but am considering just adding it to my test shot twice per week and upping the amount to about 350 IU's. Do what fits your life. Don't over complicate it.
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  11. #211
    MisterD is offline Junior Member
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    Kekel

    Are you going to do it in the same pin?

    Also my Doc is telling me to take GAC in a shot, do you know how effective it is?

    Im also trying the semoreline before HGH.

  12. #212
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Hall of Famer ~ No Source Checks
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    Haven't decided yet but I may.
    GAC is just specific amino acids in injectable form. Injections will almost always absorb better. I've read good things about it.
    I've run Sermorelin before and may again.
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  13. #213
    thetanudj is offline New Member
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    AM I ON THE RIGHT TRACK GUYS?

    Total of 8ml of Bac Water mix w/ 10.000IU hcg powder
    500iu/week will last 20 weeks

    Each injection 250IU(Monday+Thurs)
    Using "1/2 CC Insulin Syringe with 29 G X 1/2" pull out .2cc (25 units line)

    Inject onto stomach fat.

    Get 10ml Amber Sealed Vial to store mixed HCG, preload+put in freezer.

    When need take syringe out 10-15 minutes before use.

  14. #214
    kelkel's Avatar
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    No. I gave you the link with mixing instructions yesterday in another thread. Mix it as the thread says.
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  15. #215
    diehard09 is offline New Member
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    Thanks everyone. This thread has been very informative. I'm on hrt and fixing to add hcg and pregnenolone. This gives me a lot of much needed info.

  16. #216
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    FONZY007 is offline Knowledgeable Member
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    Quote Originally Posted by thetanudj View Post
    AM I ON THE RIGHT TRACK GUYS?

    Total of 8ml of Bac Water mix w/ 10.000IU hcg powder
    500iu/week will last 20 weeks

    Each injection 250IU(Monday+Thurs)
    Using "1/2 CC Insulin Syringe with 29 G X 1/2" pull out .2cc (25 units line)

    Inject onto stomach fat.

    Get 10ml Amber Sealed Vial to store mixed HCG, preload+put in freezer.

    When need take syringe out 10-15 minutes before use.


    I didn't know you can store mixed hcg in freezer, won't damage hormone?

  17. #217
    IronClydes's Avatar
    IronClydes is online now Senior Member
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    I can't tell if this thread is meaning to instruct the HRT patient on HcG to take Pregnenolone and DHEA or stating that HcG already takes care of that; rather those not on HcG need those. Anyone know?

    225, 6', 33, 15% bf, bench 320, squat 405, dead 465.

  18. #218
    NotNATTY is offline New Member
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    awesome

  19. #219
    IronClydes's Avatar
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    Quote Originally Posted by steroid.com 1 View Post

    A typical dose is 50 to 200 mg daily best taken in the morning on an empty stomach (cream applied in the morning as well). Pregnenolone is considered safe and because is converts to DHEA which leads to other hormones it's best to get your Pregnenolone levels tested before supplementing.

    DHEA Dose
     MEN
     Capsule SR micronized
     50 mg Q am
     >200 lbs 75 - 100 mg Q am
    So, as a 232 pound 34 year old man on TRT, currently on the tail end of a blast, I should be taking 75-100mg DHEA and 50-200mg Pregnenolone? That's a large range...

  20. #220
    quinnbaylor is offline Junior Member
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    Great read!! Thank you!!!

  21. #221
    Gorgos's Avatar
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    Does it applies to someone who decides to cycle for years without time off? I mean, can HCG be ran "safely" for years with appropriate dose? From what Im reading it looks like HCG is very important.

  22. #222
    Jamesmuscle is offline New Member
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    great post,very helpful.

  23. #223
    max738 is offline Junior Member
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    A lot of really good information I agree a lot of GP'S and endo"s while they should have learned about this in med school a lot of them have forgotten it or they never learned it in the first place as somebody that has worked with
    and along side many physicians some are a lot better than others.Medicine is so vast and complex anymore with all
    we are discovering each year no physician can know all there is.A really good one told me years ago that there's
    nothing hard about medicine it's knowing where to find the info when you need it.so doing your own home work
    is to your advantage.Again a really good read<Thanks

  24. #224
    jimmy liu is offline Banned
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    it is very helpful for me to have a better understanding the benifits and the difference of pregenenolone and hcg

  25. #225
    prenes is offline Junior Member
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    If you add HGC to your cycle does it cut the effectiveness of external Testosterone ? would it cut my effective dose?

  26. #226
    kelkel's Avatar
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    Not at all. It will help preserve testicular function (ITT) as well as spermatogenesis.
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  27. #227
    prenes is offline Junior Member
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    thank you for the info.

  28. #228
    High Desert Bill is offline New Member
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    Man, this is a really informative thread. I want to get on HCG as well. My doctor actually recommended it, for the shrinkage issue, but he cannot prescribe it in California. I believe I can get the DHEA at Walmart though, if I'm not mistaken.

  29. #229
    kelkel's Avatar
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    Quote Originally Posted by High Desert Bill View Post
    Man, this is a really informative thread. I want to get on HCG as well. My doctor actually recommended it, for the shrinkage issue, but he cannot prescribe it in California. I believe I can get the DHEA at Walmart though, if I'm not mistaken.

    Just be sure the dhea is micronized for best absorption.
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  30. #230
    High Desert Bill is offline New Member
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    Quote Originally Posted by kelkel View Post
    Just be sure the dhea is micronized for best absorption.
    Will do, thanks.

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