"Natty" Thought Experiment: Clomid/Aromasin vs Proviron
What would happen to a normal natural functioning male?
Clomid: 6.25-12.5mg ED
Aromasin: 6.15-12.5mg ED
Higher LH, FSH, TT, Free T
Lower E, SHBG
Prolactin???
DHT???
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Proviron Summary Mechanism of Action: https://www.steroid.com/Proviron.php#
"On a functional basis, Proviron carries four primary traits that largely define its mode of action. First and foremost the Mesterolone hormone has a strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG). In fact, it appears to be one of the strongest anabolic steroids in this regard. By binding to SHBG, a hormone partially responsible for reducing free testosterone, binding SHBG will enhance the amount of circulating free testosterone. More importantly for the anabolic steroid user, it will make a larger percentage of the anabolic steroids used available in a free rather than bound state. A simple way to look at it is the anabolic steroids you’re taking become more powerful and potent.
Proviron also has the ability to interact with the aromatase enzyme, the enzyme responsible for the conversion of testosterone to estrogen. By binding to the aromatase enzyme, Proviron can actually inhibit aromatase activity, thereby offering protection against estrogenic side effects. It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable. Depending on the nature of the cycle the individual undertakes it is quite possible for Proviron to take care of all your anti-estrogen needs.
The Mesterolone hormone will also carry a strong binding affinity to the androgen receptor. Once again this will promote the functionality of other steroids to a degree but more importantly promote enhanced metabolic activity through direct lipolysis. Then we’re left with the final issue that surrounds Proviron as a fertility medication. This is an anabolic steroid that does not suppress gonadotropins similarly to other anabolic steroids. With minimal suppression and its extremely strong androgenicity, this will enhance sperm production as androgens are necessary to spermatogenesis stimulation. This not only enhances the amount of sperm produced but greatly and equally important enhances the quality of the sperm. Before we go any further understand Proviron does have the ability to suppress gonadotropins, but there’s a line that has to be crossed for notable suppression to interfere with sperm production."
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Clomid is responsible for most hormonal rises including SHBG and Estrogen (E2). Hence the addition of an Aromatase Inhibitor (AI). But only Aromasin can lower SHBG. Not Arimidex or Letro.
But I can't find any studies or anecdotes showing an AI having an impact on prolactin or DHT.
Clomid has no impact on prolactin and raises DHT.
Could AIs change the activity expression of 5 alpha-reductase?
If a Clomid/Aromasin combo does significantly raise DHT, there shouldn't be a therapeutic difference between it and Proviron??
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Or would a Clomid/Proviron combo be better???
The Clomid can prevent any slight suppression from Proviron. The Proviron can prevent a rise in SHBG and Estrogen from the Clomid.
Most recent public case of young man doing Clomid and Proviron:
https://www.reddit.com/r/steroids/co..._will_it_work/
5+ months still on. Reports highly satisfactory results.
