I have been using 40 mcg a day for about 8 days along with adrol @50mgs a day and 25mgs proviron. At this point its really hard to say if R3 Long IGF is working. I have of course put about 5 lbs on and am getting the meanest pumps with very little water retention, but that could be form the adrol/provirion. I am wondering how I would be able to know if the R3 Long IGF is working. Also do I need to store it in the freezer or is the frig fine? Thanks to all who reply.