We know that t-3 increases IGF-1 BP at doses over 50mcg or so, using it at high doses with HGH negates the raised IGF-1 from the HGH because it'll be bound by IGF-1 BP. Which leave an expensive fat bruner and isn't working for preseving your muscle. So the advise is use AAS with t-3 to presever muscle, one of the mechinisims of AAS is raised IGF-1 but with high doses of t-3 it's binding the IGF-1 that the AAS is producing.

Here's something that will help, LR3 IGF-1 binds poorly to IGF-1 BP, so you would have elevated IGF-1 levels and IGF-1 BP couldn't bind this very well giving you the added protection your hard earned muscle need during high t-3 cycle.

I haven't tried it but it would seem that the addition of LR3 IGF-1 to the AAS during a high dose cycle of t-3 would help preserve those muscle we are all working so hard to get.

JohnnyB