
Originally Posted by
aphex
To lower endogenous GH, try taking a medication with moderate anticholinergic side effects, such as a tricyclic antidepressant, or many others (do a search).
The rationale for this is that acetycholinergic transmission is responsible for reducing the accumulation of somatostatin in the brain, which inhibits the GH secretion. Directly reducing somatostatin was the mechanism of the new drug successfully used in the recent fibromyalgia study showing that sufferers have a diminished GH response to exercise (again, do a search).
The cholinergic system is also the pathway by which Alpha GPC and Arginine purportedly induce GH release.
Short term common side effects of anticholinergic drugs are mainly dry mouth, mild constipation, anorgasmia and occasionally mental fog and blurry vision (cholinergic compounds like ALC and reminyl have the reverse effects). Having taken the former medications in the past for depression, I can assure you that for the short time you'd be taking them (one of them), the side effects would be *quite* tolerable, provided you do not exceed the dosages recommended for their respective indications (i.e. depression).
While Nolvadex, for example, may lower IGF-1, these are probably the best exogenous means of suppressing GH secretion itself.
This strategy, combined with a little sleep deprivation and feasting on high glycemic carbs (insulin suppresses GH release, as does low blood sugar potentiate it) should be your best bet.
Like one of the big dudes said, however, the clinics will make it happen.