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03-24-2006, 03:35 AM #1
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Why the necessity for long (6 month+) runs of GH?
First off, I am not arguing against the practise as there seems to be overwhelming anecdotal evidence in favour of it, nor am I trying to find a cheap alternative as I am personally 4 months into a 8 month+ jin run, I am just trying to understand why it is necessary.
The most often quoted reason seems to be that ones IGF levels are raised over time, this is the part that I don't fully understand as I was under the impression that GH and the resultant IGF is in and out of the body in a matter of hours - so how does it "build up" over the weeks & months?
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03-24-2006, 06:54 AM #2
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Well it`s all about getting the best results you can from HGH. The effects of this hormone are also most pronounced when it is used for longer periods of time, often many months long (6 months). Some do use it for shorter periods, but generally only when looking for fat loss.I have heard people doing 4 week cycles For this purpose.Other drugs also need to be used in conjunction with HGH in order to elicit the best results. Your body seems to require an increased amount of thyroid hormones, insulin and androgens while HGH levels are elevated (HGH therapy in fact is shown to lower thyroid and insulin levels). This shows that you need a cycle of a number of things to get the most from your HGH,taking a number of months.It`s a good question notsmall,let`s see what the others say...
goose...
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03-24-2006, 07:08 AM #3
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Originally Posted by goose4
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03-24-2006, 07:28 AM #4
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It`s like the claimed half-life for IGF is 6 hours,that is BALL.Where did this number come from? You got it Anabolic forum`s all over the net,it spreads like disease.I think this number of 6 months is a similar thing,but have to agree the longer your on HGH greater the results.
goose...
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03-24-2006, 07:32 AM #5
interesting question "Tiny".......................will be watching this and waiting for some answers............................
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03-24-2006, 08:01 AM #6
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Originally Posted by goose4
I've been (unsuccessfully) trying to find a post I read ages ago by Mallet saying how in his opinion you can very effectively take advantage of the nutrient shuttling capabiities of GH combined with slin PWO on much shorter runs.
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03-24-2006, 08:02 AM #7
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Originally Posted by booz
Last edited by Booz; 03-24-2006 at 08:39 AM.
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03-24-2006, 08:28 AM #8
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Progress
I am currently running a 5/2 4 i.u. per day cycle of jin. Are you doing anything else with that. What kinds of progress have you made and when did you start seeing results. Thanks
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03-24-2006, 08:42 AM #9
Originally Posted by NotSmall
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Remember.............for us to help you you need to help us....................stats and exp.........
Source checks and Ugl's to be kept to PM's
dont ask for source checks unless you have 100 posts/and 45 days minimum as a participating member.........
Booz.. a long-standing member of the AR Police:
sorry but absolutely no sources will be checked at this present time....
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03-24-2006, 09:20 AM #10
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Progress2
I am 30. Weigh About 190 5'10. had experience with test, win, deca . 5th time using gear. I want to lean down as I have always had a problem with visceral fat and I diet well and exercise regularly.
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03-24-2006, 09:44 AM #11
Right on!
Last edited by Ufa; 04-02-2006 at 11:50 PM.
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03-24-2006, 10:50 AM #12
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Originally Posted by NotSmall
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03-24-2006, 11:21 AM #13
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Originally Posted by NotSmall
Either that or that cockney fairy booz has already started abusing his new found power
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03-24-2006, 11:23 AM #14
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Originally Posted by luvinlife28
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03-24-2006, 11:28 AM #15
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Originally Posted by toolman
If you could dig up where he posted about it that would be great
What I would like clarifying about this build up of IGF is that I was under the impression that IGFs lifespan in the body was shortlived i.e. hours, so how does it build up?
I am not questioning RB's knowledge on the subject for one second, I just can't quite get my head around the above.
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03-24-2006, 12:36 PM #16
Originally Posted by NotSmall
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Remember.............for us to help you you need to help us....................stats and exp.........
Source checks and Ugl's to be kept to PM's
dont ask for source checks unless you have 100 posts/and 45 days minimum as a participating member.........
Booz.. a long-standing member of the AR Police:
sorry but absolutely no sources will be checked at this present time....
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03-24-2006, 12:39 PM #17
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Originally Posted by booz
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03-24-2006, 12:56 PM #18
Originally Posted by NotSmall
_____________________
Remember.............for us to help you you need to help us....................stats and exp.........
Source checks and Ugl's to be kept to PM's
dont ask for source checks unless you have 100 posts/and 45 days minimum as a participating member.........
Booz.. a long-standing member of the AR Police:
sorry but absolutely no sources will be checked at this present time....
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03-24-2006, 01:46 PM #19
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Originally Posted by booz
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03-24-2006, 02:33 PM #20
Originally Posted by toolman
_____________________
Remember.............for us to help you you need to help us....................stats and exp.........
Source checks and Ugl's to be kept to PM's
dont ask for source checks unless you have 100 posts/and 45 days minimum as a participating member.........
Booz.. a long-standing member of the AR Police:
sorry but absolutely no sources will be checked at this present time....
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03-24-2006, 02:49 PM #21
Originally Posted by NotSmall
for fat loss?
anyway i think:little increments in results, accumulated over long periods and maybe works through blocking myostatin (over 8 ius block 20-40 %).
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03-24-2006, 03:56 PM #22
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Originally Posted by oswaldosalcedo
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03-24-2006, 07:11 PM #23
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but sry to maybe hujack a bit is it true that it will grow the cancer cells as well????? every one has cancer cells so if it will make them bigger you are in more danger of a cancer! what do you think? thank you?
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03-25-2006, 05:17 AM #24
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Originally Posted by arnold_of_malta
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03-25-2006, 05:20 AM #25
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So no one has a definitive answer as to why GH must be run a minimum of 6 months?
And yet we all continue to tell people that this is the way it must be done.
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03-25-2006, 09:06 AM #26
if the reason is: because it takes a while to buildup igf values in the liver...why not just take igf in that case...there should be more reasons of the long term thing of hgh
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03-25-2006, 05:21 PM #27
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Originally Posted by fred9
If the main reason for muscle growth on GH is caused by elavated igf1 levels and gains with growth are said to happen gradually over time then why are cycles of igf1 itself recomended to be short in duration as igf1 receptors quickly become saturated.
I posted this question along time ago with no reply.
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03-25-2006, 05:33 PM #28
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Originally Posted by j martini
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03-26-2006, 05:59 PM #29
Originally Posted by NotSmall
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03-26-2006, 06:02 PM #30
Originally Posted by fred9
"High Dose Growth Hormone Exerts an Anabolic Effect at Rest and during Exercise in Endurance-Trained Athletes
M. L. Healy, J. Gibney, D. L. Russell-Jones, C. Pentecost, P. Croos, P. H. Sönksen and A. M. Umpleby
Department of Diabetes and Endocrinology, GKT School of Medicine, St. Thomas Hospital, London, United
r-hGH-treated
------------------ Baseline --------- 1Wk-----------4 Wk--------- /Placebo-
IGF-I (nmol/liter) 24.6 ± 3.0 / 89.6 ± 12.21-- 106.3 ± 16.41/ 25.8 ± 2.7-- 25.4 ± 2.7-- 25.2 ± 2.6
fT3 (pmol/liter) 5.1 ± 0.3 6.0 ± 0.12 6.1 ± 0.22 4.8 ± 0.2 4.9 ± 0.2 4.8 ± 0.1
fT4 (pmol/liter) 15.5 ± 1.5 11.5 ± 1.02 10.6 ± 0.92 15.8 ± 1.6 15.6 ± 1.7 15.8 ± 1.5
Testosterone (nmol/liter) 18.3 ± 3.2 18.5 ± 3.4 18.5 ± 3.3 16.7 ± 2.6 16.3 ± 2.6 16.4 ± 2.2
Glucose (mmol/liter) 4.7 ± 0.3 5.5 ± 0.5 5.3 ± 0.2 4.5 ± 0.4 4.2 ± 0.2 4.4 ± 0.3
Insulin (mU/liter) 7.9 ± 1.6 22.6 ± 3.92 16.0 ± 9.32 6.0 ± 0.3 5.6 ± 1.9 9.3 ± 2.4
HOMA IR 1.4 ± 0.2 5.1 ± 1.02 3.3 ± 0.62 1.1 ± 0.4 1.0 ± 0.3 1.6 ± 0.5
Total cholesterol (mmol/liter) 4.3 ± 0.3 4.0 ± 0.5 4.1 ± 0.3 3.4 ± 0.3 3.3 ± 0.3 3.5 ± 0.6
Triglyceride 1.1 ± 0.2 2.0 ± 0.5 1.3 ± 0.1 0.6 ± 0.1 0.7 ± 0.1 0.5 ± 0.1
LDL cholesterol (mmol/liter) 2.6 ± 0.3 2.2 ± 0.3 2.3 ± 0.3 1.6 ± 0.4 1.6 ± 0.3 1.6 ± 0.5
HDL cholesterol (mmol/liter) 1.2 ± 0.1 1.0 ± 0.1 1.1 ± 0.1 1.5 ± 0.1 1.5 ± 0.1 1.7 ± 0.2
Body weight (kg) 74.4 ± 1.1 76.5 ± 1.72 77.9 ± 1.62 74.9 ± 3.4 74.9 ± 3.4 74.7 ± 3.3
Lean body mass (kg) 57.6 ± 1.1 61.0 ± 1.22 61.6 ± 2.5 61.8 ± 2.4
Total body fat (kg) 11.4 ± 1.4 11.6 ± 1.7 9.8 ± 1.9 10.1 ± 2.0
Trunk fat (kg) 4.7 ± 0.7 4.5 ± 0.9 2.8 ± 0.9 2.8 ± 0.9
There was no change in igf-I levels in the placebo-treated group throughout the observation period. In contrast, in the r-hGH-treated group, IGF-I levels rose markedly, reaching levels outside the physiological range (P < 0.001; Table 2 ). These changes occurred within 7 d of commencing r-hGH administration and did not change further over the remaining 21-d period of r-hGH administration.Last edited by oswaldosalcedo; 03-26-2006 at 06:07 PM.
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03-26-2006, 07:15 PM #31
Interesting Info! What were the dosages used?
Originally Posted by oswaldosalcedo
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03-26-2006, 11:17 PM #32
Originally Posted by oswaldosalcedo
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03-27-2006, 01:18 PM #33
Here's a link to a similar (shorter time) study
http://jcem.endojournals.org/cgi/con...8/11/5221#SEC2
The dosage was:
at a dose of 0.067 mg/kg body weight daily
Anybody know how to convert mg to IUs?
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03-27-2006, 01:37 PM #34
Originally Posted by fred9
1.33 mg around 4 ius.
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03-27-2006, 02:40 PM #35
Originally Posted by oswaldosalcedo
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03-27-2006, 03:09 PM #36
It wasn't sited as a guide for dosing....it was sited for info regarding the speed of IGF buildup.
Originally Posted by Hard Head
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03-27-2006, 03:30 PM #37
Originally Posted by Triposinator
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03-27-2006, 04:10 PM #38
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Originally Posted by Hard Head
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03-27-2006, 07:20 PM #39
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Why 6 months? Why not 4 months? Why not 7 months? Is the best HGH cycle for life? We just don`t know,I`m going to stick with 10 months on 2 months off.To be honest it all means very little,it`s all about the dose to get results I want.It`s all a little overated,all about the dose....but I`m with my boy nots here.......................
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03-30-2006, 01:58 PM #40
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Thanks RB
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