Could you help me please (endurance&athletics)

[kr13]

Hello. I'm from europe. I'm 22 year old and I train athletic (midle distance). This year I try with some steroid and other staff. First I dose oxandrolone then clenbuterol.After that I take 20.000 UI of EPO. Now I dose IGF and LH+FSH, because of non predictable doping control. I'm not satisfied with this cycle.
For second part of season now I have 1 months (but yust 2 week "dirty" substance - I must hide because of doping control).

I think i will take EPO now in this two week and than IGF and LH+FSH?
What would you think! What would you advise to me? How much of EPO and how (iv or im)?

Tkanks very much.

[mSHY8]

USE EPOSINO brand epo at 4000iu 3x/week for three weeks and follow with a maintenance dose. Much info on EPO is available online. Search through Google for "EPOSINO".

[mSHY8]

oh, also inject SC not IM!

[Ironman06]

Ban This Eposino Idiot!!!!!

[Carlito B]

There are EPO mimetting peptides like this one below:

Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP1.

Johnson DL, Farrell FX, Barbone FP, McMahon FJ, Tullai J, Hoey K, Livnah O, Wrighton NC, Middleton SA, Loughney DA, Stura EA, Dower WJ, Mulcahy LS, Wilson IA, Jolliffe LK.

R. W. Johnson Pharmaceutical Research Institute, Drug Discovery Research, Raritan, New Jersey 08869, USA. [email protected]

To obtain information about the functional importance of amino acids required for effective erythropoietin (EPO) mimetic action, the conserved residues of a peptide mimetic of EPO, recently discovered by phage display, were subjected to an alanine replacement strategy. Further, to identify a minimal mimetic peptide sequence, a series of truncation peptides has been generated. One EPO mimetic peptide sequence, EMP1, was targeted and more than 25 derivatives of this sequence were evaluated for their ability to compete with [125I]EPO for receptor binding and for their ability to support the proliferation of two EPO-responsive cell lines. Two hydrophobic amino acids, Tyr4 and Trp13, appear essential for mimetic action, and aromatic residues appear to be important at these sites. These findings are consistent with the previously reported X-ray crystal structure of EMP1 complexed with the extracellular domain of the EPO receptor (EPO binding protein; EBP). In our efforts to define the structural elements required for EPO mimetic action, a 13 amino acid peptide was identified which possesses mimetic properties and contains a minimal agonist epitope. The ability of this peptide to effectively serve as a mimetic capable of the induction of EPO-responsive cell proliferation appears to reside within a single residue, equivalent to position Tyr4 of EMP1, when present in a sequence that includes the cyclic core peptide structure. Although these peptides are less potent than EPO, they should serve as an excellent starting point for the design of compounds with EPO mimetic activity.

PMID: 9521688 [PubMed - indexed for MEDLINE]



Working on this one and narrowed it down to 3 peptides, soon will be decided which is best.

Thanks,

C

[simm]

I would not play with EPO......