IGF-1 LR3 low dosage

[Pensilneck]

Next sample is from one of Dave Palumbos column.

"Anecdotal reports by Long R3 IGF-1 users suggest that 10-20mcg per day of Long R3 IGF-1 causes significant muscle cell hypertrophy, and will continue to do so extremely effectively for apptoximately 30 days"

Is that dosage totally waste of money? Sounds pretty low to me....

[Pensilneck]

Is this real that nobody has nothing to say?

[Zelos]

very interesting .
i will follow your thread .

thanks for the infos .

[angrynewyorker]

Dave Palumbo is very knowledgeable when it comes to performance enhancing drugs. I have seen guys on here say to take 200mcg a day of igf 1 and they are just throwing their money away. Dave talks about receptor downgrade because of too high a dose of igf 1. and also daves physique speaks for itself. I guarantee the guys taking 200mcg a day look nothing like the jumbo one nuff said

[Pensilneck]

Here is the hole article, sounds interesting and sheap way to go?

[rodge]

and also daves physique speaks for itself. I guarantee the guys taking 200mcg a day look nothing like the jumbo one nuff said

did'nt he do time cause of selling fake hgh??? so much for his credibility

-rodge

[Titan1]

Dave Palumbo is very knowledgeable when it comes to performance enhancing drugs. I have seen guys on here say to take 200mcg a day of igf 1 and they are just throwing their money away. Dave talks about receptor downgrade because of too high a dose of igf 1. and also daves physique speaks for itself. I guarantee the guys taking 200mcg a day look nothing like the jumbo one nuff said

Did you know that in clinical studies children were given 2-7mg thats 2000mcg-7000mcg of igf-1 per day whithout any problems so if a child can take it so can an adult and i think that the problem is just that people dont take high enough doses ,but im not saying you need to take 2mg of course

[big an rich]

Most of the people I know have taken 100mcg a day only on training days in the muscle worked. I think this sounds like a good way to use the drug.

[Pensilneck]

What`s your opinions about that 20mcg/ed dosage?? Only on training days, after training........

[smiler]

hasven't used it...yet, but everything i've heard and read, including profiles on several boards, say "less than 50mcg/ or more than 120mcg ed is a waste" i am interested if anyone has truly had good results on a lower dose, good question.

[Pensilneck]

hasven't used it...yet, but everything i've heard and read, including profiles on several boards, say "less than 50mcg/ or more than 120mcg ed is a waste" i am interested if anyone has truly had good results on a lower dose, good question.

Seem like everybody who has tryed IGF-1 LR3 has done it with over 50mcg dosage...??

[JJP480]

It is my first kick at the cat but I have been doing 60mcg sub-q on training days and have found it works quite well . I wouldn't go any lower though .

[Snrf]

I'm pretty sure perfectbeast used 40mcg into each muscle an he got good results...

And what do you mean subq jon480, I thought it was just im ?

yeah beast was using 40 mcg into each muscle post 176
Beast's Workout Log

[JJP480]

You can administer it suq-q also . I have one shot in the AM and one PWO . I have had excellent results .
I will try IM next round and compare .

[SPIKE]

I have ran doses of 40mcg-120mcg ED. The higher the dose the better resutls were produced.

According to my results I've been sticking with 80-100mcg. I could definitely see a dose like 20mcg work if it were continual over months. I cycle my dose and agree with Palumbo about downregulation b/c after about 40 days or so at 100mcg my gains come to a hault.

I dont see getting those wicked pumps and rapid BF loss at 20mcg but I"m sure over time it can and will have it's benefits. I get way too good of results at 80-100mcg so I'll let other give 20mcg a whirl. Just do us all a favor and report back..

[Travbedaman]

"Originaly posted by Grunt 76 over at I B E"

What do we want? Bigger muscles. More muscle cells that we will later grow with exercise and gear. A pump? Fatloss? Yeah, right. You can get a pump with a good "pump" product for a quarter of the price of IGF-1. Fatloss? Clen /Alb and T3/T4 will give it to you again at a fraction of the price of IGF-1. More muscle cells, you can ONLY get with IGF-1 (and MGF too). Nothing else will give it to you and if you are using IGF-1 for anything else, you are misusing it. More muscle cells is CLEARLY the best use for IGF-1.

What does all this tell us?

It tells us that we should use IGF-1 to make more muscle cells. It's the only thing that can give it to us and more cells is more growth, which is our goal.

What does this tell us?

The localized effects are the best. Long R3 IGF-1 can float around your body and attach to anything that has IGF-1 receptors. The intestines is the place that has the MOST IGF-1 receptors and it also happens to have lots of blood flow. Injecting large amounts of Long R3 ENSURES that you are growing your intestines. Remember, more cells doesn't equal more size right away. Wait a bit, and see them grow.

What does this mean?

It means that if you are injecting upwards of 50mcg of IGF-1 you are growing your intestines. Yes you are also growing muscle and you may be getting leaner in the process. Your waistline looks trimmer. Nice. A few months down the line, your new intestinal cells will be of their full adult size and you will have acquired the perma-bloat look. Guaranteed. Maybe not Coleman-size perma-gut, but SOME perma-gut and it will keep growing. Guaranteed. Just as your new muscle cells can keep growing and growing IF you pin IGF-1 in a way to maximize new muscle cell creation.

HOW?

Heavy resistance exercise strongly upregulates the IGF-1 receptors on the stressed muscle. That means that after your workout, the muscles you trained are at their BEST STATE for receiving IGF-1 and growing many new cells. That's when you pin. This upregulation of IGF-1 receptor during exercise is short-lived. The science is not readily available so I am unable to quote a paper, but within 60 minutes of the last set, the receptors are back at baseline. This means, PIN IMMEDIATELY POSTWORKOUT and you will get your new muscle cells. PIN A LESSER AMOUNT and you will get only new MUSCLE cells out of your IGF-1. Pin more and you will grow other things, including stuff you wish you didn't grow.

What else?

All the talk about IGF-1's half-life is UTTER BULLSHIT. It is technicality without any real-world applicability. Yes rhIGF-1 has a "short half-life". But what does it mean? It means that it is either taken up by a cell receptor or bound up by a binding protein in short order. Does it mean that 20 minutes after the IGF-1 is pinned you should pin more because "blood levels are low"? Not by any means. Once it's activated a cell receptor, that's where it initiates a cellular response that will take about 72 hours to be complete and which will consume lots of energy. So the half-life of 20 minutes means NOTHING BECAUSE THE EFFECTS STILL LAST 72 HOURS ALL THE SAME.

What about Long R3 IGF-1?

Yes technically it has a longer half-life. Why? Because it either gets rapidly taken up by a cell receptor or... Just floats around. Until it can find a receptor or is destroyed by the immune system or some other metabolizing mechanism. BUT THIS MEANS ***NOTHING***!!! Why does it mean nothing? BECAUSE once it attaches to a cell receptor, it initiates a cellular response that will take about 72 hours to be complete. THIS CELLULAR RESPONSE IS ALL THAT INTERESTS US. Not "blood levels", that's utter bullshit. As a matter of fact, the one thing YOU DO NOT WANT IS FOR BLOOD LEVELS OF IGF-1 TO BE ELEVATED. Because that means you are growing everywhere and this means first and foremost your guts. Sure it feels like it's working while you're on. Just you wait 9 months and see that you look like Craig Kovacs. Bravo, you now have the biggest intestines in the world.

Half-life means nothing. Localized vs systemic = bad argument. You want localized effects. Period. You get them by pinning immediately postworkout. Period. End of argument.

OMFG I am so tired of all the misinformation floating around on IGF-1. Look at the length of this post. Did you read all of it? You should, you know.

[bigacct]

"Originaly posted by Grunt 76 over at I B E"

What do we want? Bigger muscles. More muscle cells that we will later grow with exercise and gear. A pump? Fatloss? Yeah, right. You can get a pump with a good "pump" product for a quarter of the price of IGF-1. Fatloss? Clen /Alb and T3/T4 will give it to you again at a fraction of the price of IGF-1. More muscle cells, you can ONLY get with IGF-1 (and MGF too). Nothing else will give it to you and if you are using IGF-1 for anything else, you are misusing it. More muscle cells is CLEARLY the best use for IGF-1.

What does all this tell us?

It tells us that we should use IGF-1 to make more muscle cells. It's the only thing that can give it to us and more cells is more growth, which is our goal.

What does this tell us?

The localized effects are the best. Long R3 IGF-1 can float around your body and attach to anything that has IGF-1 receptors. The intestines is the place that has the MOST IGF-1 receptors and it also happens to have lots of blood flow. Injecting large amounts of Long R3 ENSURES that you are growing your intestines. Remember, more cells doesn't equal more size right away. Wait a bit, and see them grow.

What does this mean?

It means that if you are injecting upwards of 50mcg of IGF-1 you are growing your intestines. Yes you are also growing muscle and you may be getting leaner in the process. Your waistline looks trimmer. Nice. A few months down the line, your new intestinal cells will be of their full adult size and you will have acquired the perma-bloat look. Guaranteed. Maybe not Coleman-size perma-gut, but SOME perma-gut and it will keep growing. Guaranteed. Just as your new muscle cells can keep growing and growing IF you pin IGF-1 in a way to maximize new muscle cell creation.

HOW?

Heavy resistance exercise strongly upregulates the IGF-1 receptors on the stressed muscle. That means that after your workout, the muscles you trained are at their BEST STATE for receiving IGF-1 and growing many new cells. That's when you pin. This upregulation of IGF-1 receptor during exercise is short-lived. The science is not readily available so I am unable to quote a paper, but within 60 minutes of the last set, the receptors are back at baseline. This means, PIN IMMEDIATELY POSTWORKOUT and you will get your new muscle cells. PIN A LESSER AMOUNT and you will get only new MUSCLE cells out of your IGF-1. Pin more and you will grow other things, including stuff you wish you didn't grow.

What else?

All the talk about IGF-1's half-life is UTTER BULLSHIT. It is technicality without any real-world applicability. Yes rhIGF-1 has a "short half-life". But what does it mean? It means that it is either taken up by a cell receptor or bound up by a binding protein in short order. Does it mean that 20 minutes after the IGF-1 is pinned you should pin more because "blood levels are low"? Not by any means. Once it's activated a cell receptor, that's where it initiates a cellular response that will take about 72 hours to be complete and which will consume lots of energy. So the half-life of 20 minutes means NOTHING BECAUSE THE EFFECTS STILL LAST 72 HOURS ALL THE SAME.

What about Long R3 IGF-1?

Yes technically it has a longer half-life. Why? Because it either gets rapidly taken up by a cell receptor or... Just floats around. Until it can find a receptor or is destroyed by the immune system or some other metabolizing mechanism. BUT THIS MEANS ***NOTHING***!!! Why does it mean nothing? BECAUSE once it attaches to a cell receptor, it initiates a cellular response that will take about 72 hours to be complete. THIS CELLULAR RESPONSE IS ALL THAT INTERESTS US. Not "blood levels", that's utter bullshit. As a matter of fact, the one thing YOU DO NOT WANT IS FOR BLOOD LEVELS OF IGF-1 TO BE ELEVATED. Because that means you are growing everywhere and this means first and foremost your guts. Sure it feels like it's working while you're on. Just you wait 9 months and see that you look like Craig Kovacs. Bravo, you now have the biggest intestines in the world.

Half-life means nothing. Localized vs systemic = bad argument. You want localized effects. Period. You get them by pinning immediately postworkout. Period. End of argument.

OMFG I am so tired of all the misinformation floating around on IGF-1. Look at the length of this post. Did you read all of it? You should, you know.

Great repost my man! I believe in this 100%. Palumbo has a scientific backround because of his undergraduate degree and partial Med school. I don't care that he was busted for selling "fake" GH. That has nothing to do with the science behind how IGF-LR3 works. This read is echoed by SS01 too. It's all about the science. Less is more.

[Pensilneck]

Thanks Travbedaman, that was great and helpfull post.
I`l try that 20mcg after workout, 5 days on, 2 off. 4 weeks on, 4 weeks off, 4 weeks on.
Same time I take massive dosage of AAS...

I`l report you guys

[Skills]

Great repost my man! I believe in this 100%. Palumbo has a scientific backround because of his undergraduate degree and partial Med school. I don't care that he was busted for selling "fake" GH. That has nothing to do with the science behind how IGF-LR3 works. This read is echoed by SS01 too. It's all about the science. Less is more.

SS01 is Grunt76 and this is exactly why i hired him to advise me.

[gdubb216]

I realise this reply has nothing to do with the subject matter of this post, but I am however going to comment on Dave Palumbo's credibility. I had the pleasure
or misfortune you could say of spending about 5 months with Dave. He trained with me He taught me how to diet he basically showed me things that I didn't think were possible...he did all this without anabolics or supplementation. He tolerated my all bitching and moaning. He never lost patience with me. He did this all just because I approached him and asked him
for his help. I was 280 pounds when I met Dave. I couldn't even bench 135 couldn't do a pushup by the end of those 5 months I had lost 80 POUNDS was
able to hit about 225 and since then I still am improving and getting better.
Dave Palumbo is probably the most knowledgeable person when it comes to Performance Enhancing drugs I have ever met. And I have picked many physician's brains about these subjects as well as many so-called experts.
In everything I learned from Dave Palumbo in reference to training, diet, anabolics & hormones, injury, proper excersise form, he was never wrong he has helped me achieve goals. he is a down to earth person willing to help anyone he can because he truly enjoys teaching and helping people I usually I just read stuff on this board and many others for knowledge. I realise non of u guys know me and I have no credibility this like my second post ever. I am not a individual claiming to have all the answers All can I say IS HE ISN"T CALLED THE ANABOLIC FREAK FOR NOTHING!!!

[Ironman5151]

I have ran doses of 40mcg-120mcg ED. The higher the dose the better resutls were produced.

According to my results I've been sticking with 80-100mcg. I could definitely see a dose like 20mcg work if it were continual over months. I cycle my dose and agree with Palumbo about downregulation b/c after about 40 days or so at 100mcg my gains come to a hault.

I dont see getting those wicked pumps and rapid BF loss at 20mcg but I"m sure over time it can and will have it's benefits. I get way too good of results at 80-100mcg so I'll let other give 20mcg a whirl. Just do us all a favor and report back..

can't wait to hear your results.

[Columbus]

do you guys ever do pec inj? where else ? best/worst?

[ecivon]

do you guys ever do pec inj? where else ? best/worst?

I do 80mcgs ed pwo, 40 mcgs each side. Bi's, tri's, delt's and pec's. Piece of cake. In the morning I'll bust the muscle group I'm working for the day and then shoot immediately after. That night I'll go back to the gym and speed rep the muscles I shot in the morning. Great pumps and muscle hardness.

[Columbus]

OT? they need to rest bro........

[Pensilneck]

What`s your opinion about lenght of the IGF-1 LR3 cycle if use only 20-25mcg/PWO 3 times/week....

Can I take it straigh for months or do I have to keep some "holiday" during the cycle.

[Pensilneck]

BUMB! Somebody? Is it wise to take it straight for about 3 moths if I hit it only 3 times/week. PWO, 20mcg

[JJP480]

4 weeks on 4 or more off.
After about 30 days receptors downgrade.
I was running 50 mcgs PWO and bumped it up to 80mcgs and noticed a huge difference.
Stick to 80 - 100mcgs.

[Ironman5151]

Good info JJP. Thanks for sharing.

[Pensilneck]

4 weeks on 4 or more off.
After about 30 days receptors downgrade.
I was running 50 mcgs PWO and bumped it up to 80mcgs and noticed a huge difference.
Stick to 80 - 100mcgs.

I hit only 20mcg/PWO, 3 times/week and I have notice sick pumps every single muscle i train. Great stuff! Whith the prices whe have here I never go up to 20mcg. 100e/100mcg...............LOL

[JJP480]

Next time you run igf just for shits n giggles shoot PWO 80mcgs for 2 weeks. Just PWO and see how you like it. It's like Special K cereal....give it two weeks LOL .
It was well worth the money. IMO.

[lemons]

jjp didnt you read the post by Travbedaman
80-100 mcg is crazy i really dont want to grow anything but what im shooting into there are many ost on this new info and its pretty scary cause ive shot 75mcg ed for 5 weeks a year ago and i did notice my gut get larger so if you want to grow your intestines go for it have fun 80-100 will do you right

[lemons]

bump

[badboy247]

surely for intestinal growth your talking about injecting over a period closer marginalised by months not weeks or days?? and in addition surely this is also sub-q shots not i-m's. your saying you were shooting i/m and you had intestinal growth over a matter of a few weeks ????

[JJP480]

IM is the way to go PWO only. I like the 80mcgs far better than the 50mcgs.