Does IGF1LR3 cause hyperplasia?

[jg42058p]

Does IGF1LR3 cause hyperplasia?

Someone said that it does on another thread, and I want to confirm the truth behind this with the mods

[TRA]

Hyperplasia of what? Hyperplasia is just growth of cells, i.e. new cells, say, in an organ, which then make the organ bigger. But you need to figure out what you're concerned with getting bigger to ask the question.

[MuscleScience]

most likely not in any significant amount.

[Deio]

most likely not in any significant amount.

What do you mean by that? Either your musclecells can split into two or they don't? I've heard that 9 months of usage is required to make your cells split once.

[MuscleScience]

What do you mean by that? Either your musclecells can split into two or they don't? I've heard that 9 months of usage is required to make your cells split once.

The commonly accepted view in the science community is that muscle cells do not undergo mitosis under normal physiological conditions, mean excluding neoplasms or viral infections. Muscle cells are highly specialized cells that have lost the ability to undergo mitosis. Having said that there is also some supporting evidence that under some circumstances that muscle cells can be elicited to divide.

The reason that I said that its not likely in any significant amount is because I do know of literature that has shown muscle cells to be able to be induced to divide, in vitro. But I have seen very few studies that have been reproducible that show this in vivo. So as a scientifically minded person I can not say with absolute certainty that it does not happen some where in some muscle in the body.

My point is that if it did happen to any large degree that it would be very obvious. Cells undergoing mitotic division show up very very well under the microscope.

[jg42058p]

interesting responses. thanks guys

[TRA]

Ah, hyperplasia of the muscles, gotcha. Doubtful, and agree with above.