Interesting study on GH and Protein Metabolism

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Clin Nutr. 2009 Sep 19. [Epub ahead of print] Links


Growth hormone and protein metabolism.


Moller N, Vendelbo MH, Kampmann U, Christensen B, Madsen M, Norrelund H, Jorgensen JO.
Medical Department M (Endocrinology & Diabetes), Aarhus University Hospital, DK 8000 Aarhus, Denmark and Clinical Institute, Aarhus University, DK 8000 Aarhus, Denmark.


Growth hormone (GH) and intracellular STAT 5 signalling represents a very old regulatory system and, whereas insulin dominates periprandially, GH may be viewed as the primary anabolic hormone during stress and fasting. GH exerts metabolic effects both directly and through stimulation of IGF-I, insulin, and free fatty acids (FFA). When well nourished the GH-induced stimulation of IGF-I and insulin is important for tissue anabolism whereas during fasting and other catabolic states GH predominantly stimulates the release and oxidation of FFA which leads to decreased glucose and protein oxidation and preservation of LBM. The most prominent metabolic effect of GH is a marked increase in lipolysis and FFA levels. In the periprandial and postabsorptive states the effects of GH on protein metabolism are modest and include increased protein synthesis and decreased breakdown at the whole body level and in muscle together with decreased amino acid degradation/oxidation and decreased hepatic urea formation. During fasting and stress the effects of GH on protein metabolism become more pronounced; lack of GH during fasting increases protein loss and urea production rates by approximately 50% with a similar increase in muscle protein breakdown. The importance of GH is further substantiated by the observations that adult patients with GH-deficiency are obese and have reduced LBM, and impaired physical performance and acr*****ly is characterised by increased LBM and decreased fat mass.

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GH + Slin = Growth

GH Alone = Fatloss without muscle loss


Just proves how important a compound like GH could be during pre-competition.

GH + Slin + Test = Synergy!

[astrix79]

i run slin 10I.U pwo
then pwo shake
+20min i take HGH 8I.U

and im on test + other AAS.

how mush slin is needed?
should i take slin during the day?

i dont care about fat lose....just wanna gain and build mass...