IGF receptors in the intestine...IGF-1 = gut?

[bber99]

So I came across an article on pubmed stating how the intestines have a VERY high amount of igf1 receptors. So this seems problematic becasue IGF will attach to everything (correct me if I'm wrong) and not just have localized effects.

So, I was looking at using a peptide protocol for bigger arms/calves, but this scares me because I definitely don't want any abdominal distension...

Soo...is there a safe protocol to avoid this? Perhaps its dose dependent? Or is it just something you have to deal with and hope you get lucky?

[Belial10732]

So I came across an article on pubmed stating how the intestines have a VERY high amount of igf1 receptors. So this seems problematic becasue IGF will attach to everything (correct me if I'm wrong) and not just have localized effects.

So, I was looking at using a peptide protocol for bigger arms/calves, but this scares me because I definitely don't want any abdominal distension...

Soo...is there a safe protocol to avoid this? Perhaps its dose dependent? Or is it just something you have to deal with and hope you get lucky?

There are receptors in the gut, but that doesn't mean the smooth muscle and epithelial cells in the intestines are going to grow from the administration of IGF-1 the way skeletal muscle will. Just because they have the RTK for IGF-1 doesn't mean they behave the same way.

It's an old "bro science" myth.

[ScotchGuard02]

The IGF receptors are most active immediately after a hard workout. Thus the localized bilateral injection directly into the worked muscles immediately after workout. The IGF isn't going to be absorbed 100% into the worked muscles. It'll float throughout the body. That's why I only do about 60mcg, 30mcg per side. The theory is that most of the IGF will be attach to the worked muscles and less will float to the intestines. The other school of thought is to go 100mcg ED for a month and get off IGF. I like the lower dose every 3rd day for a longer period of time.

[ramacher]

What gauge needle are you using Scotch and what does bilaterally do differently than straight on? I have some legit rhIGF-1 and I am trying to get some localized effect so you are suggesting 30mcg in left and right so 60 mcg daily on days you do weights?

[ScotchGuard02]

I'm using Beckton Dickinson 30ga insulin syringes. Bilaterally just means you pin both arms or body part equally. rhIGF-1 is good stuff. I only pin immediately after I lift. I go into a bathroom stall immediately after workout and pin. I don't even drive home first. I pin every other day or every 3rd day. But my cycle is 3 to 4 months.

[ramacher]

Do you bring your 'lunch box' full of ice? LOL. Do you only pin after workout or do you also in addition pin an hour later as well because of the short half life? Do you do 30 days or longer?

[ScotchGuard02]

I preload a syringe with 60mcg of IGF and I carry it to the gym in a hard eye glasses case. I workout for an hour so it doesn't hurt the IGF to sit in the eye glasses case in my gym bag. I pin every other day or every 3rd day, 50mcg to 60mgc for 3 to 4 months.

[ramacher]

this is LR3 I assume, not rh?

[Lifeguard102]

My friend likes to microdose lr3.
More is absorbed and less floats .
20mcg x3 IM.

[ramacher]

Hey when you pin after weights, do you also do cardio as well right after? Or do you get some protein in you between pinning and cardio?

[ScotchGuard02]

I pin after my workout. If it's my cardio day, I lift then do cardio and pin after cardio.

[ramacher]

Gotcha. So you do 30mcg on the left and right side for 30 days and then resume 30 days later.