Peptide Guru's (GET IN HERE)

[PK-V]

Got me some CJC (DAC) & HEX (GHRH + GHRP stack)

took 100mcg's of each last night to assess tolerance

nothing!

no feeling like crap for 15+ mins like when you take MTII
or no hunger stim like when you take GHRP-6

I'm liking this already

Cutting at the min

clen/t3/low dose test/diet/cardio

how would you guys set up this combo to help me along

how often should I be hitting up the cjc due to the extended half life?

should there be any issues with desensitazation with using these?

should I be concerned about prolactin?

any other comments

I plan on running 100mcg's of each (tri-daily) morning/post wo/before sleep

over kill?

I have 4mg total of each pep to burn

thanks

[956Vette]

Generally wouldn't rely on the extended CJC life, dose alongside your hex as you have. Twice daily is sufficient most days...third inject is a bonus. Hard to help on what to expect, given there is less than 10mg. good luck!

[PK-V]

Thanks Vette

Gonna get some more if I feel it's doing anything for me

[M302_Imola]

Why are you using CJC w/ DAC? You do know that DAC will cause GH bleed which you don't want! You should be using mod GRF1-29 or CJC-1295 no DAC as far as a GHRH paired w/ your GHRP. IMO, Hex is a poor choice of a GHRP as I believe GHRP-2 or Ipamorelin are superior. Did you do your homework before jumping into peptides?

[956Vette]

Why are you using CJC w/ DAC? You do know that DAC will cause GH bleed which you don't want! You should be using mod GRF1-29 or CJC-1295 no DAC as far as a GHRH paired w/ your GHRP. IMO, Hex is a poor choice of a GHRP as I believe GHRP-2 or Ipamorelin are superior. Did you do your homework before jumping into peptides?

I wouldnt be overly concerned with utilizing CJC DAC, however going forward I like the recommendation of GRF w/ GHRP-2 and/or IPA for next month. Best of luck!

[PK-V]

Huh!

However, unlike
GHRP-6, hexarelin does not induce food intake because of its incapability to drastically increase the grehlin
levels that are responsible for the feeling of hunger and faster emptying of the gastric system. But the
studies of Deghenghi et al. (1994) reported that hexarelinpossessed similar effectiveness in stimulating the
GH release in a long-lasting event and slightly more effective than the GHRP-6. These are supported by a
number of studies. Locatelli et al. (1999) reported that hexarelin provides protection and healing especially
for the cardiac dysfunction and abnormalities.

The most-studied Ghrelin mimetic peptides are GHRP-2, GHRP-6, hexarelin, and ipamorelin. Of these, ipamorelin is the least potent GH releasing compound but the compound that also has the least effect on cortisol and prolactin release. GHRP-6 is more potent with slightly more cortisol and prolactin release; GHRP-2 is more potent still; and hexarelin is the most potent of the four, with the most release of cortisol and prolactin as well. [3]

[3]Ghigo, E., Arvat, E., Muccioli, G. and Camanni, F. (1997) Growth hormone releasing peptides. Eur. J. Endocrinol. 136, 445–460



In relation to my DAC CJC I see no reason not to try it out especially in relation to my goal of modifying my body composition, if the HGH administration frequency vs effects studies are anything to go by

Consistent release fat loss vs Larger spike for an anabolic effect

It's CJC with the steroid equivalent of an ester, I can switch it up to CJC (non/DAC) when I get back to bulking for that der enhanced IGF-1 secretion post wo

Thanks for the input!

[M302_Imola]

Huh!

However, unlike
GHRP-6, hexarelin does not induce food intake because of its incapability to drastically increase the grehlin
levels that are responsible for the feeling of hunger and faster emptying of the gastric system. But the
studies of Deghenghi et al. (1994) reported that hexarelinpossessed similar effectiveness in stimulating the
GH release in a long-lasting event and slightly more effective than the GHRP-6. These are supported by a
number of studies. Locatelli et al. (1999) reported that hexarelin provides protection and healing especially
for the cardiac dysfunction and abnormalities.

The most-studied Ghrelin mimetic peptides are GHRP-2, GHRP-6, hexarelin, and ipamorelin. Of these, ipamorelin is the least potent GH releasing compound but the compound that also has the least effect on cortisol and prolactin release. GHRP-6 is more potent with slightly more cortisol and prolactin release; GHRP-2 is more potent still; and hexarelin is the most potent of the four, with the most release of cortisol and prolactin as well. [3]

[3]Ghigo, E., Arvat, E., Muccioli, G. and Camanni, F. (1997) Growth hormone releasing peptides. Eur. J. Endocrinol. 136, 445–460



In relation to my DAC CJC I see no reason not to try it out especially in relation to my goal of modifying my body composition, if the HGH administration frequency vs effects studies are anything to go by

Consistent release fat loss vs Larger spike for an anabolic effect

It's CJC with the steroid equivalent of an ester, I can switch it up to CJC (non/DAC) when I get back to bulking for that der enhanced IGF-1 secretion post wo

Thanks for the input!

ok you can copy and paste but do you truly understand the compounds you are about to put in your body? I suggest you stop by Dat's forum and do some more research on peptides. Yes GHRP-6 induces hunger in some so it wouldn't be the best for a cut but GHRP-2 releases more GH than GHRP-6 and doesn't have the hunger side effects. Hex to me is behind the times and there are far better choices. Also, your idea of CJC w/ DAC being a better fat burning choice is wrong. It's the large pulses of GH that help w/ fat burning and also have an anabolic effect. That steady stream that CJC DAC induces is going to lead to saturation and desensitivity.

[PK-V]

I copy and paste because it's the science yet you dispute it based on? broscience it seems

Elaborate on how hex is behind it's time! (im waiting)

Also your wrong again...



Researchers from the University of Michigan in Ann Arbor found that the mode of administration of growth hormonesupplements was important for achieving optimal effects. Continuous administration of GH caused the highest levels of IGF -1. Growth hormone exerts most of its anabolic effects by stimulating the production of IGF -1 in the liver and in tissues throughout the body. Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat. (Journal Clinical Endocrinology and Metabolism, 94: 2828-2834, 2009)

[M302_Imola]

I copy and paste because it's the science yet you dispute it based on? broscience it seems

Elaborate on how hex is behind it's time! (im waiting)

Also your wrong again...



Researchers from the University of Michigan in Ann Arbor found that the mode of administration of growth hormonesupplements was important for achieving optimal effects. Continuous administration of GH caused the highest levels of IGF -1. Growth hormone exerts most of its anabolic effects by stimulating the production of IGF -1 in the liver and in tissues throughout the body. Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat. (Journal Clinical Endocrinology and Metabolism, 94: 2828-2834, 2009)

Here is a post written by DATBTRUE on GHRP's, you will see that Hex isn't the greatest choice:

GHRP-6 at the saturation dose 100mcg does not really increase prolactin & cortisol but may do so slightly at higher doses. This rise is still within the normal range.

GHRP-2 is a little more efficacious then GHRP-6 at causing GH release but at the saturation dose or higher may produce a slight to moderate increase in prolactin & cortisol. This rise is still within the normal range although doses of 200 - 400mcg might make it the high end of the normal range.

Hexarelin is the most efficacious of all of the GHRPs at causing an increase in GH release. However it has the highest potential to also increase cortisol & prolactin. This rise will occur even at the 100mcg saturation dose. This rise will reach the higher levels of what is defined as normal.
Desensitization

GHRP-6 can be used at saturation dose (100mcg) three or four times a day without risk of desensitization.

GHRP-2 probably at saturation dose several times a day will not result in desensitization.

Hexarelin has been shown to bring about desensitization but in a long-term study the pituitary recovered its sensitivity so that there was not long-term loss of sensitivity at saturation dose. However dosing Hexarelin even at 100mcg three times a day will likely lead to some down regulation within 14 days.

Notice in the article you posted it states "Administering GH several times during the day had the greatest effects on fat metabolism. Taking growth hormone once a day is best for maximizing its anabolic effects, while taking it several times a day is best for decreasing body fat". Notice it says taking GH several times a day is best for decreasing body fat...now are you confusing several w/ continuous? Several means multiple doses throughout the day...continuous means a constant GH release which DAC would give you. Also, the author confuses me by using GH in a lot of places where he should be using peptides. I'm confused if he wrote this pertaining to synthetic GH or endogenous GH pulsed from peptides.

[spywizard]

the best way to see it, i had a client that was on a test deca cycle his 4th cycle.. he's 49 yrs old and 12bf, typically a 12 week cycle will net him 12 lbs of new weight.. 8 muscle and 4 fat.. all keep able..

I had him do 200mcg ghrp6 3x day
cjc non/dac 200mcg day

the end results after 12 weeks is he gained the 12 lbs as expected however he was still at 12%bf..

he is very pleased with the results..

Now with that said.. 12 lbs is not a lot on a test/deca cycle, he uses a very strict diet, 500-1000 cals above his maintenance requirement

[PK-V]

the best way to see it, i had a client that was on a test deca cycle his 4th cycle.. he's 49 yrs old and 12bf, typically a 12 week cycle will net him 12 lbs of new weight.. 8 muscle and 4 fat.. all keep able..

I had him do 200mcg ghrp6 3x day
cjc non/dac 200mcg day

the end results after 12 weeks is he gained the 12 lbs as expected however he was still at 12%bf..

he is very pleased with the results..

Now with that said.. 12 lbs is not a lot on a test/deca cycle, he uses a very strict diet, 500-1000 cals above his maintenance requirement

Thanks for sharing!

It seems peptide are truly finding there place among the mix of so many compounds

GHRP-6 for me was a serious appetite stimulant, not something I could take on a cut

[BLACK RAVEN]

hey there, im just starting on frag, completely by its self, 500mcg daily just to see if over a 4 week period it has any effect on mucle mass, i know it says its supposed to cut BF but i have read so many mixed reviews...does this stuff really work?

[BLACK RAVEN]

oh and i mixed 1ml of injection water into 5mg of frag which gives me 500mcg @ 10iu is this right?

[RuhlFreak55]

I'm having a little trouble following the DAC vs no DAC argument here, looking at running some peptides myself and would like to clarify this argument

[M302_Imola]

I'm having a little trouble following the DAC vs no DAC argument here, looking at running some peptides myself and would like to clarify this argument

Ok what you want with GHRP/GHRH(CJC) is pulses in GH. The body endogenously releases GH in pulses so the use of GHRP/GHRH is to strengthen or make a larger spike in GH. What you don't want is a small steady realease of GH in which CJC w/ DAC will give (aka GH Bleed). The body will become desensitized and most likely won't produce large GH pulses. There is a graph on the home page of datbtrue's forum that shows all of this info. You should really do yourself a favor (if you're considering peptides) and join over there. You will be amazed at the amount of info on peptides over there.