Morning VS night gh injects

[UFO]

I apologize if this topic has been covered in the past. I figured I would make a new thread since age in this matter has a lot to do with what kind of answers I will get.
I have 5 AAS cycles under my belt and wanted to try gh on my next run this winter. I will be 25. Was going to run the GH with a Test C/Deca cycle. Starting the gh about a month before my AAS cycle, working from 3ius up to 5iu during my blast. My biggest concern is how lazy/zombie like people will get off of good gh when they inject first thing in the morning. I also understand the reasoning behind this is to not mess with your natural gh which pulses strongest during sleep. The last thing I want to do is mess with my natural gh and have to run it for the rest of my life. Do any of you guys have experience running both ways(morning vs night)? Any blood work results to show that night time injects did mess with your natural GH? Very open to help/suggestions on this one as I am new to gh world. Thanks for your time and help.

[ScotchGuard02]

I've used both pharma and bluetops for the past 5 years at 5iu/ed. I never really got tired like a zombie. I do know that HGH affects people differently. You're 25? I would recommend you wait a few years before you get into HGH.

[UFO]

Not being a smart ass at all, but why do you recommend waiting a few years with GH? I understand the reasoning behind waiting in age with AAS(shutting down your HPTA) but GH is even prescribed to children for use. Not sure if they must then use synthetic gh for life though like TRT. Thanks for the input

[gixxerboy1]

I done both ways and prefer evening injections

[DanB]

I've used both pharma and bluetops for the past 5 years at 5iu/ed. I never really got tired like a zombie. I do know that HGH affects people differently. You're 25? I would recommend you wait a few years before you get into HGH.

I felt lethargic at the start of running pharm GH, mabey it my own fault for jumping straight onto 4i.u, like you said it effects everybody different

OP for what its worth, if you cant obtain legit pharm GH then I honestly wouldnt bother, while scotch and couple other members who I respect their opinions, have said they gotten legit generics, these are few and far between, more chance of getting bunk then legit

And to answer your question, depending on your dose, and assuming it legit, it takes 3hr (sarge, gix, marcus etc if this incorrect then inform me, it off top my head so may be out slightly?) for the GH to clear and your biggest natural pulse it at night when you sleep, so you pin before bed you miss the natural pulse because the exgenerous GH will prevent it

Personally I like to pin in the a.m

On the other hand, if you pin 3+ hr or more before bed then you still get natty pulse, best of both worlds, lie I said the 3hr could be incorrect, it may well be 4hr, I can pull up some data tomorrow if necessary............

If I was you I would look into peptides, mod grf 1-29 and ghrp/ipa,

I dont know if you can pm yet due to post count, but if you want more info on the peps then let me know

[gixxerboy1]

this was taken from Marcus

I'm just doing some research on this and look what Ive found, even after 4 days of exogenous gh your natural gh is still suppressed so if this is true you completely suppress your natrual production while your injecting daily anyway!!


Changes in Non-22-Kilodalton (kDa) Isoforms of Growth Hormone (GH) after Administration of 22-kDa Recombinant Human GH in Trained Adult Males1
Jennifer D. Wallace, Ross C. Cuneo, Martin Bidlingmaier, Per Arne Lundberg, Lena Carlsson, Cesar Luiz Boguszewski, John Hay, Massoud Boroujerdi, Antonio Cittadini, Rolf Dall, Thord Rosén and Christian J. Strasburger

Metabolic Research Unit (J.D.W., R.C.C., J.H.), Department of Medicine, and Statistics Section, Department of Social and Preventative Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Australia; Neuroendocrine Unit (M.B., C.J.S.), Department of Medicine, Innenstadt University Hospital, 80336 Munich, Germany; Serviço do Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (C.L.B.), 80060-240 Curitiba, Brasil; Research Centre for Endocrinology and Metabolism (P.A.L., L.C., T.R.), Sahlgrenska Hospital, Gothenberg, S-413 45 Sweden; Department of Endocrinology (M.B.), St. Thomas’s Hospital, London SE1 7EH, United Kingdom; Department of Internal Medicine and Cardiovascular Sciences (A.C.), Frederico II University, 80131 Naples, Italy; and Department of Medicine M (Endocrinology and Diabetes) (R.D.), Aarhus University Hospital, Aarhus, 8000 Denmark

Address all correspondence and requests for reprints to: Jennifer D. Wallace, Metabolic Research Unit, University of Queensland, Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia. E-mail: jwallace@medicine.pa.uq.edu.au.

GH is being used by elite athletes to enhance sporting performance. To examine the hypothesis that exogenous 22-kDa recombinant human GH (rhGH) administration could be detected through suppression of non-22-kDa isoforms of GH, we studied seventeen aerobically trained males (age, 26.9 ± 1.5 yr) randomized to rhGH or placebo treatment (0.15 IU/kg/day for 1 week). Subjects were studied at rest and in response to exercise (cycle -ergometry at 65% of maximal work capacity for 20 min). Serum was assayed for total GH (Pharmacia IRMA and pituitary GH), 22-kDa GH (2 different 2-site monoclonal immunoassays), non-22-kDa GH (22-kDa GH-exclusion assay), 20-kDa GH, and immunofunctional GH. In the study, 3 h after the last dose of rhGH, total and 22-kDa GH concentrations were elevated, reflecting exogenous 22-kDa GH. Non-22-kDa and 20-kDa GH levels were suppressed. Regression of non-22-kDa or 20-kDa GH against total or 22-kDa GH produced clear separation of treatment groups. In identical exercise studies repeated between 24 and 96 h after cessation of treatment, the magnitude of the responses of all GH isoforms was suppressed (P < 0.01), but the relative proportions were similar to those before treatment. We conclude: 1) supraphysiological doses of rhGH in trained adult males suppressed exercise-stimulated endogenous circulating isoforms of GH for up to 4 days; 2) the clearest separation of treatment groups required the simultaneous presence of high exogenous 22-kDa GH and suppressed 20-kDa or non-22-kDa GH concentrations; and 3) these methods may prove useful in detecting rhGH abuse in athletes.
*Anyone wanting a source check from a willing

[gixxerboy1]

So you are going to be suppressed no matter what time you take it. Thats why younger guys notice less from gh because if they take a low dose and shut down their production there isnt a real net gain. I also take it before bed because of the insulin resistance. It gives me a long time fasting after i inject

[ramacher]

From my understanding, the most anyone produces is going to be around 2IU at the peak of adolescence and it declines from there. Regardless of age, 4IU is doubled what anyone will produce at their peak, and they should see results if you do that everyday. Please correct me if I am wrong.

[marcus300]

this was taken from Marcus

I'm just doing some research on this and look what Ive found, even after 4 days of exogenous gh your natural gh is still suppressed so if this is true you completely suppress your natrual production while your injecting daily anyway!!


Changes in Non-22-Kilodalton (kDa) Isoforms of Growth Hormone (GH) after Administration of 22-kDa Recombinant Human GH in Trained Adult Males1
Jennifer D. Wallace, Ross C. Cuneo, Martin Bidlingmaier, Per Arne Lundberg, Lena Carlsson, Cesar Luiz Boguszewski, John Hay, Massoud Boroujerdi, Antonio Cittadini, Rolf Dall, Thord Rosén and Christian J. Strasburger

Metabolic Research Unit (J.D.W., R.C.C., J.H.), Department of Medicine, and Statistics Section, Department of Social and Preventative Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Australia; Neuroendocrine Unit (M.B., C.J.S.), Department of Medicine, Innenstadt University Hospital, 80336 Munich, Germany; Serviço do Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (C.L.B.), 80060-240 Curitiba, Brasil; Research Centre for Endocrinology and Metabolism (P.A.L., L.C., T.R.), Sahlgrenska Hospital, Gothenberg, S-413 45 Sweden; Department of Endocrinology (M.B.), St. Thomas’s Hospital, London SE1 7EH, United Kingdom; Department of Internal Medicine and Cardiovascular Sciences (A.C.), Frederico II University, 80131 Naples, Italy; and Department of Medicine M (Endocrinology and Diabetes) (R.D.), Aarhus University Hospital, Aarhus, 8000 Denmark

Address all correspondence and requests for reprints to: Jennifer D. Wallace, Metabolic Research Unit, University of Queensland, Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia. E-mail: jwallace@medicine.pa.uq.edu.au.

GH is being used by elite athletes to enhance sporting performance. To examine the hypothesis that exogenous 22-kDa recombinant human GH (rhGH) administration could be detected through suppression of non-22-kDa isoforms of GH, we studied seventeen aerobically trained males (age, 26.9 ± 1.5 yr) randomized to rhGH or placebo treatment (0.15 IU/kg/day for 1 week). Subjects were studied at rest and in response to exercise (cycle -ergometry at 65% of maximal work capacity for 20 min). Serum was assayed for total GH (Pharmacia IRMA and pituitary GH), 22-kDa GH (2 different 2-site monoclonal immunoassays), non-22-kDa GH (22-kDa GH-exclusion assay), 20-kDa GH, and immunofunctional GH. In the study, 3 h after the last dose of rhGH, total and 22-kDa GH concentrations were elevated, reflecting exogenous 22-kDa GH. Non-22-kDa and 20-kDa GH levels were suppressed. Regression of non-22-kDa or 20-kDa GH against total or 22-kDa GH produced clear separation of treatment groups. In identical exercise studies repeated between 24 and 96 h after cessation of treatment, the magnitude of the responses of all GH isoforms was suppressed (P < 0.01), but the relative proportions were similar to those before treatment. We conclude: 1) supraphysiological doses of rhGH in trained adult males suppressed exercise-stimulated endogenous circulating isoforms of GH for up to 4 days; 2) the clearest separation of treatment groups required the simultaneous presence of high exogenous 22-kDa GH and suppressed 20-kDa or non-22-kDa GH concentrations; and 3) these methods may prove useful in detecting rhGH abuse in athletes.
*Anyone wanting a source check from a willing

So you are going to be suppressed no matter what time you take it. Thats why younger guys notice less from gh because if they take a low dose and shut down their production there isnt a real net gain. I also take it before bed because of the insulin resistance. It gives me a long time fasting after i inject

Correct ^^^^^

[UFO]

Thanks for the replies. So I take from this that injection time is not important since it will surpress it no matter what. At 25since the peak of my natural GH is behind me will running GH now at this age really effect me in the long run in terms of natural production? And to the poster asking if I can get pharma GH, no but I do have legit rips that have been verified by several members on my other board with blood tests(serum and igf) and came direct from the lab. Thanks again

[gixxerboy1]

the serum test is meaningless. Gh has to be bio available to actually work. The test doesnt tell you either way. There are plenty of guys who used rips on here and switched to pharm grade cause the rips are junk

[DanB]

And to answer your question, depending on your dose, and assuming it legit, it takes 3hr (sarge, gix, marcus etc if this incorrect then inform me, it off top my head so may be out slightly?) for the GH to clear and your biggest natural pulse it at night when you sleep, so you pin before bed you miss the natural pulse because the exgenerous GH will prevent it

If I was you I would look into peptides, mod grf 1-29 and ghrp/ipa,

(DAN)There was method to this madness, again the copy and paste is coming, studys/charts show that basically the younger you are (within reason), the larger a pulse that a mod grf/ghrp can signal, since you produce more natty when younger and all the peps do is signal the max your body can produce, you older and produce less GH then it stands to reason that any pulse you signal will be smaller then somebody 5,10,20yr younger

this was taken from Marcus

I'm just doing some research on this and look what Ive found, even after 4 days of exogenous gh your natural gh is still suppressed so if this is true you completely suppress your natrual production while your injecting daily anyway!!

(DAN) this is interesting and going against what I have read elsewhere, and on very low dosage also,


Changes in Non-22-Kilodalton (kDa) Isoforms of Growth Hormone (GH) after Administration of 22-kDa Recombinant Human GH in Trained Adult Males1
Jennifer D. Wallace, Ross C. Cuneo, Martin Bidlingmaier, Per Arne Lundberg, Lena Carlsson, Cesar Luiz Boguszewski, John Hay, Massoud Boroujerdi, Antonio Cittadini, Rolf Dall, Thord Rosén and Christian J. Strasburger

Metabolic Research Unit (J.D.W., R.C.C., J.H.), Department of Medicine, and Statistics Section, Department of Social and Preventative Medicine, University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Australia; Neuroendocrine Unit (M.B., C.J.S.), Department of Medicine, Innenstadt University Hospital, 80336 Munich, Germany; Serviço do Endocrinologia e Metabologia do Hospital de Clínicas da Universidade Federal do Paraná (C.L.B.), 80060-240 Curitiba, Brasil; Research Centre for Endocrinology and Metabolism (P.A.L., L.C., T.R.), Sahlgrenska Hospital, Gothenberg, S-413 45 Sweden; Department of Endocrinology (M.B.), St. Thomas’s Hospital, London SE1 7EH, United Kingdom; Department of Internal Medicine and Cardiovascular Sciences (A.C.), Frederico II University, 80131 Naples, Italy; and Department of Medicine M (Endocrinology and Diabetes) (R.D.), Aarhus University Hospital, Aarhus, 8000 Denmark

Address all correspondence and requests for reprints to: Jennifer D. Wallace, Metabolic Research Unit, University of Queensland, Department of Medicine, Princess Alexandra Hospital, Brisbane 4102, Australia. E-mail: jwallace@medicine.pa.uq.edu.au.

GH is being used by elite athletes to enhance sporting performance. To examine the hypothesis that exogenous 22-kDa recombinant human GH (rhGH) administration could be detected through suppression of non-22-kDa isoforms of GH, we studied seventeen aerobically trained males (age, 26.9 ± 1.5 yr) randomized to rhGH or placebo treatment (0.15 IU/kg/day for 1 week). Subjects were studied at rest and in response to exercise (cycle -ergometry at 65% of maximal work capacity for 20 min). Serum was assayed for total GH (Pharmacia IRMA and pituitary GH), 22-kDa GH (2 different 2-site monoclonal immunoassays), non-22-kDa GH (22-kDa GH-exclusion assay), 20-kDa GH, and immunofunctional GH. In the study, 3 h after the last dose of rhGH, total and 22-kDa GH concentrations were elevated, reflecting exogenous 22-kDa GH. Non-22-kDa and 20-kDa GH levels were suppressed. Regression of non-22-kDa or 20-kDa GH against total or 22-kDa GH produced clear separation of treatment groups. In identical exercise studies repeated between 24 and 96 h after cessation of treatment, the magnitude of the responses of all GH isoforms was suppressed (P < 0.01), but the relative proportions were similar to those before treatment. We conclude: 1) supraphysiological doses of rhGH in trained adult males suppressed exercise-stimulated endogenous circulating isoforms of GH for up to 4 days; 2) the clearest separation of treatment groups required the simultaneous presence of high exogenous 22-kDa GH and suppressed 20-kDa or non-22-kDa GH concentrations; and 3) these methods may prove useful in detecting rhGH abuse in athletes.
*Anyone wanting a source check from a willing

So you are going to be suppressed no matter what time you take it. Thats why younger guys notice less from gh because if they take a low dose and shut down their production there isnt a real net gain. I also take it before bed because of the insulin resistance. It gives me a long time fasting after i inject

I now where your going and what you mean, but if you pulse the GH and incoporate peps then younger the better basically (within reason), as your prob aware, by using peps to signal the pulse then followed by GH it will send the natty pulse through the roof to put it bluntly and also prolong it and in theory it wont supress endgenerous GH, the before mentioned charts, studys, articles which shall be posted over weekend (hopefully) will argue this point better then I could ever manage to articulate with my limited voculabary

I havnt mastered the multiquote like some others here hence my crude attempt at replying to the posts lol

Actually I might start a thread on GH pulsation in the near future and see if I can get any opinions on it as it dosnt seem to be discussed much, if at all over here............

[gixxerboy1]

i'd be interested to read it Dan

[DanB]

I'll copy/paste from dats forum (shhhh) hopefully by Sat, just I travelling alot last few weeks so only online a few mins here and there, and there so much on his forum you could spend a couple hrs easily pulling stuff off it,

Leave it with me..........

[Chuckdiesel]

I'll copy/paste from dats forum (shhhh) hopefully by Sat, just I travelling alot last few weeks so only online a few mins here and there, and there so much on his forum you could spend a couple hrs easily pulling stuff off it,

Leave it with me..........

Days the man when it comes to peps and gh. I'm currently incorporation his method of using sat dose of ghrp/grf people followed by 2.5 iu of growth 10 minutes later. I'm also injecting another 2 iu of growth before bed. I'm loving this method and haven't had any issues thus far. As a side note UFO, I do experience a bit of lethargy when I do a morning workout and inject my peps/growth people...this usually occurs many hours after injecting.

[Chuckdiesel]

Days the man when it comes to peps and gh. I'm currently incorporation his method of using sat dose of ghrp/grf people followed by 2.5 iu of growth 10 minutes later. I'm also injecting another 2 iu of growth before bed. I'm loving this method and haven't had any issues thus far. As a side note UFO, I do experience a bit of lethargy when I do a morning workout and inject my peps/growth people...this usually occurs many hours after injecting.

Dat not day...stupid auto correct.

[Chuckdiesel]

Man auto correct is kicking my ass...replace people with pwo to make more sense

[Sgt. Hartman]

So you are going to be suppressed no matter what time you take it. Thats why younger guys notice less from gh because if they take a low dose and shut down their production there isnt a real net gain. I also take it before bed because of the insulin resistance. It gives me a long time fasting after i inject

^^^^Exactly. Taking any significant amount of GH will shut down the bodies' natural production based on GH levels and IGF-1 levels so if being suppressed is something you don't want to deal with then stay away from GH or run peps like Dan suggested.

I've ramped up to well over 5iu first thing am and never felt the least bit tired or like a zombie.