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"After a just a little researching I think the deducted optimal dose for humans of 2 mg per week is way off.
It appears some bodybuilders came to that conclusion simply by using the mg/kg (or mg /lb) of bodyweight dosage used in horse and directly apllying it to humans.
The dosage recommended for a horse being 10mg/week and the average horse weighing 1000lbs, they deducted that the dosage for a 200lbs bodybuilder should be 2mg per week.
But this isnt how you do animal to human dosage conversion.
Check this article out
http://www.fasebj.org/content/22/3/659.full.pdf
According to this article, a correct formula to calculate human dosage from animal dosage in the following :
Human dose (mg/kg) = Animal dose (mg/kg) x Animal Km/Human Km
The article includes a conversion table that gives us the different values of that Km factor for different species, including humans. Unfortunately horses are not included (they aren't lab animals).
BUT they do give a value of Km for dogs.
And we do have a recommended dosage of TB500 for greyhounds : 5mg per week . This comes from the original TB500 manufacturer, MediVet, which is where we got the 10mg/week dosage for horses.
Now if the average geryhound weighs 32kg, the dose in mg/kg is 5/32=0.15625mg
The table included in the article gives us :
Dog Km = 20
Human Km = 37
So
Human TB500 dose = 5/32 x 20/37= 25/296 or approx 0.084459mg/kg
So the correct human dose for a for a 200lbs = 90.7kg man
should be 7,66mg per week
Of course its only a gross approximation but it's probably much closer the the correct efficient dose than the 2mg/week that has been talked about until now."