Test Results Are In: Pharma HGH vs China HGH

I'm posting this on a new thread since I think that many will find this very interesting. I conducted a test to compare Pharma Grade HGH (Serostim) to China HGH. I used bloodwork to measure both GH Serum and IGF-1.

The Test

I took Serostim pharma HGH for several years and the last 8 months took 5IU ED. I took my first blood test 1 hour after pinning 5IU fasted. After this first blood test, I switched to China HGH - same dosage and then retested. Here are the results:

After long term use of Serostim Pharma HGH 5iu ED

Growth Hormone Serum - 3.2
IGF-1 - 501

After 6 days of China HGH 5iu ED

Growth Hormone Serum - 4.6
IGF-1 - 517

So what does this say? It appears that the China HGH is as good as the Serostim. Is that the case? I have read many on this board say that all China HGH is bunk. These tests don't seem to support that. What do you think?

Would this be the "yellow top" Chinese HGH?

I think Chinese is bunk. Regardless of bloods. All I've ever got from Chinese hgh is side effects. Even if the numbers are good the results are nil.

There are other things to consider then the serum GH reading. The 191 amino acids structure can be correct but if it is missfolded during the manufacturing process it will be rendered useless and can actually cause health issues in the long run...the folding of protein is the most technically difficult part of the manufacturing and this is where a lot of difference lays between pharm and generic.

Quote:

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Originally Posted by MIKE_XXL

There are other things to consider then the serum GH reading. The 191 amino acids structure can be correct but if it is missfolded during the manufacturing process it will be rendered useless and can actually cause health issues in the long run...the folding of protein is the most technically difficult part of the manufacturing and this is where a lot of difference lays between pharm and generic.

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Interesting. How would you test for that?

I am not sure you actually can. The molacular weight would be the same, all the 191 amino acids would be present in the sequence...so most standard testing would only look at these items.

Here is some interesting read on the subject of protein folding.

Protein Misfolding and Degenerative Diseases | Learn Science at Scitable

There have been in a FEW good generics in the PAST but it's been a long time since I've used a generic.
I learned something new today about the 'protein misfolding'

They use many things in the generics to fool blood test, growth releasing peps etc. Also what Mike states is 100% correct when I was dealing with some major HGH manufacturers who were registered and approved to sell HGH in China actually sold me fakes and the reason is the black market because they know we cant do anything to complain.

I contacted a biochemist who has 20yrs experience in analytical chemistry and investigating the structure and function of biomolecules, his specialties are proteomics, mass spectrometry, post translational modifications, NMR, membrane biochemistry and is also a teacher and speak on the subject. He also tested some generics. He is a email from him explaining what can be done when testing the hormone

Hi Marcus,
there are some things that we can do, some things that we could do, but that would possibly be too expensive (not worth it) and other things that we cannot do.

Please let me start with the last section:

e absolutely cannot test any substances for their suitability for any purpose, particularly not for their use in a diagnostic, therapeutic and/or recreational purpose, when this invloves administering to a living being (including humans).

Measuring the concentration of the growth hormones is something that is actually not as easy as it might seem. The concentration of the hormone can have two different meanings, it could be the chemical concentration of a compound (this is something that we can measure), it could also be the biological activity of this compound (this would be different, if a certain proportion of this chemical would be biologically inactive, which could happen for a variety of reasons). The latter (measuring the biological activity) is something we cannot do. We can measure the chemical concentration of human growth hormone (or any other growth hormone), but that would involve the chemical synthesis of an internal standard, followed by a fairly complicated experiment, in which we use chemical scissors (en enzyme called trypsin) to chop the protein into pieces, then we analyse these pieces using a combination of high performance liquid chromatography and mass spectrometry, followed by a computer-intensive analysis of the data. The result of this experiment would be the concentration either in units of mol/l or in units of mg/l (the two are interconvertible). I do not know how the IU (stands for International Units) for growth hormone are defined - this might be a functional (biological) unit (which we cannot measure).

Human growth hormone is a chain of 191 different amino acids. One thing we can do is measure the total molecular weight of the protein in a sample to see, if it corresponds to the molecular weight that would be predicted for a protein containing these 191 amino acids. This experiment detects, if one amino acid was missing or another one was added, in some cases (but not in all cases) even, if an amino acid was replaced with a different one. Another outcome of this experiment would be to see, if other, similar proteins are present in the same sample.

In a different experiment we can check, if a protein in a particular sample is really growth hormone or if it is possibly something completely different, for example egg white protein or milk protein.
Regards
************

Your also up against the blood testing because its a mine field to get right especially when they add in other growth releasing compounds and in many case some harmful substances what will make you extremely ill and could kill you. I wouldn't take nothing from your results except stick with 100% pharm grade hgh and you will see a huge difference between the two and never think you can buy cheap hgh because the machine what makes the hormone active costs millions so when you put this up against the morals of the Chinese who poison there own people with, do you really think they are going to bottle 100% hgh to the black market!!

I was paid off the keep my mouth shut about one company what I caught selling fake hgh but I still posted about them.

There is only one option imho, don't buy Chinese gh and stick with pharm grade.

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Originally Posted by DGenRit

I'm posting this on a new thread since I think that many will find this very interesting. I conducted a test to compare Pharma Grade HGH (Serostim) to China HGH. I used bloodwork to measure both GH Serum and IGF-1.

The Test

I took Serostim pharma HGH for several years and the last 8 months took 5IU ED. I took my first blood test 1 hour after pinning 5IU fasted. After this first blood test, I switched to China HGH - same dosage and then retested. Here are the results:

After long term use of Serostim Pharma HGH 5iu ED

Growth Hormone Serum - 3.2
IGF-1 - 501

After 6 days of China HGH 5iu ED

Growth Hormone Serum - 4.6
IGF-1 - 517

So what does this say? It appears that the China HGH is as good as the Serostim. Is that the case? I have read many on this board say that all China HGH is bunk. These tests don't seem to support that. What do you think?

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Isn't IGF-1 the reason we take hGH? the hGH signals the liver to produce IGF-1, correct? If that number is high, then don't we get the benefit of hGH? If not, then please explain it to me.

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Originally Posted by oldnsedentary

Isn't IGF-1 the reason we take hGH? the hGH signals the liver to produce IGF-1, correct? If that number is high, then don't we get the benefit of hGH? If not, then please explain it to me.

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Like ive said sometimes they put other peps inside to fool you and you cant get igf-1 anymore its all the other related igf's like lr3 which are completely useless at building tissue and the Chinese actually have compounds to fool tests normal this compound does increase the bp drastically but its not even worth testing its just a waste just stick with pharm grade if you cant get it leave it well alone.

Quote:

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Originally Posted by marcus300

Like ive said sometimes they put other peps inside to fool you and you cant get igf-1 anymore its all the other related igf's like lr3 which are completely useless at building tissue and the Chinese actually have compounds to fool tests normal this compound does increase the bp drastically but its not even worth testing its just a waste just stick with pharm grade if you cant get it leave it well alone.

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Marcus - are you saying that the Chinese can put things in that will fool he test into thinking there is IGF-1 in the blood? I just don't see how they can do that. Manipulating the GH serum I understand through adding peptides. But actual IGF-1 showing up in your blood work?

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Originally Posted by DGenRit

Marcus - are you saying that the Chinese can put things in that will fool he test into thinking there is IGF-1 in the blood? I just don't see how they can do that. Manipulating the GH serum I understand through adding peptides. But actual IGF-1 showing up in your blood work?

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They use growth releasing peps aswell as many other compounds they have manufactured to fool test, they know that you can test if the hormone is active or not so that's why sometimes they put hgh but its useless, other times they put dangerous compounds in what mimic hgh sides and other to fool blood work. To be honest just read the whole of the Chinese concerns thread and you will see everything there develop.

If your happy buying cheaper generics and think its working carry on but I wouldn't touch them again and personally only use pharm grade, there is no cheap version. Ive used hgh on and off for many years and dealing with a country what is the heart of counterfeited goods and also been exposed many times for fake hgh to the black market personally its not worth the risk.

Please read the Chinese concerns thread and if your still happy carry on but I wouldn't have 100,000 ius free.

I'm with you Marcus. I sticking with my Serostim. Just not worth the risk for me. I've had great results in Sero and am getting a good price now so I'm sticking with Pharma. Thanks for sharing this info. It's very informative.

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Originally Posted by DGenRit

I'm with you Marcus. I sticking with my Serostim. Just not worth the risk for me. I've had great results in Sero and am getting a good price now so I'm sticking with Pharma. Thanks for sharing this info. It's very informative.

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Thank you for your topic DGenRit. I will be the defector within the ranks here. As an experienced user of ghrh, ghrh, igf-1 & rhgh I agree that the Chinese product delivers value. Going forward my serostim budget is a fraction of the equation. Not to discount the risks mentioned in this thread and others...that is not my intent. Chinese growth ftw. jmho.

I hear ya. I just don't want to have to worry - and I'm willing to pay for that peace of mind. Now I'm stuck with several kits of China HGH.