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Thread: Insulin increases free testosterone

  1. #1
    fiddlesticks's Avatar
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    Insulin increases free testosterone

    https://www.ncbi.nlm.nih.gov/m/pubmed/7852532/ (insulin blocker lowers test and free test)

    This is very interesting.

    Perhaps a low dose of insulin could be used in place of TRT for possibly better results than the TRT itself as the total T is worthless, free T being what matters.. Slow acting insulin+ AI= awesome gains? I think so!
    Last edited by fiddlesticks; 12-05-2018 at 04:43 PM.

  2. #2
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    Your reasoning is flawed.
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    Quote Originally Posted by Bonaparte View Post
    Your reasoning is flawed.
    The easier thing to say would be "keto lowers test" i suppose.

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    insulin lowers both Cortisol and SHBG (thus allowing more free test). insulin also increases the rate at which the liver converts T4 into T3.
    these things are all great for bodybuilding purposes, but none of them are to such a high degree that by themselves they would make any huge difference. they are really just small "bonuses"
    even if using exogenous insulin your still gong to benefit from a Cortisl blocker like Cytradren or Winstrol , still going to benefit from running high dosages of test with some Proviron to raise free T, and still going to benefit from running T4/T3.

    it is interesting none the less to see the many benefits insulin has on multiple other hormones in the body.
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    Quote Originally Posted by GearHeaded View Post
    insulin lowers both Cortisol and SHBG (thus allowing more free test). insulin also increases the rate at which the liver converts T4 into T3.
    these things are all great for bodybuilding purposes, but none of them are to such a high degree that by themselves they would make any huge difference. they are really just small "bonuses"
    even if using exogenous insulin your still gong to benefit from a Cortisl blocker like Cytradren or Winstrol , still going to benefit from running high dosages of test with some Proviron to raise free T, and still going to benefit from running T4/T3.

    it is interesting none the less to see the many benefits insulin has on multiple other hormones in the body.
    Not only does insulin convert t4 to t3 it also slightly lowers reverse t3 which is amazing, ive been contemplating taking 1iu of insulin R before my 50mcg cytomel to potentiate it. A concoction of insulin, albuterol and T3 would be a golden combo to raise free T3 and lower rT3

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    Quote Originally Posted by GearHeaded View Post
    insulin lowers both Cortisol and SHBG (thus allowing more free test). insulin also increases the rate at which the liver converts T4 into T3.
    these things are all great for bodybuilding purposes, but none of them are to such a high degree that by themselves they would make any huge difference. they are really just small "bonuses"
    even if using exogenous insulin your still gong to benefit from a Cortisl blocker like Cytradren or Winstrol , still going to benefit from running high dosages of test with some Proviron to raise free T, and still going to benefit from running T4/T3.

    it is interesting none the less to see the many benefits insulin has on multiple other hormones in the body.
    Wait, wait, wait hold on a minute here
    You're saying there is such a thing as cortisl blockers? Has anyone here ever taken something like this, what would it do and what are the effects or sides?
    Is this a health supplement or an actual pharma grade medicine you need a script for??
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    Quote Originally Posted by EDCG19 View Post
    Wait, wait, wait hold on a minute here
    You're saying there is such a thing as cortisl blockers? Has anyone here ever taken something like this, what would it do and what are the effects or sides?
    Is this a health supplement or an actual pharma grade medicine you need a script for??
    A ton of things are "cortisol blockers" ranging from sex to pop tarts.

    For serious though there are multiple pharmaceutical options like mirtazapine, insulin , steroids .. Ive used mirtazapine which is the most potent of the three and it made me unable to participate in life for 3 days, i have never been that sedated in my life. Cortisol is important..
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    Quote Originally Posted by EDCG19 View Post
    Wait, wait, wait hold on a minute here
    You're saying there is such a thing as cortisl blockers? Has anyone here ever taken something like this, what would it do and what are the effects or sides?
    Is this a health supplement or an actual pharma grade medicine you need a script for??
    as far as Cortisol blockers used for bodybuilding purposes , your talking all script drugs , so Winstrol (which you've heard of I'm sure), Cytadren (which works as an anti estrogen on top of being a cortisol suppressant.. this drug is more popular among 'gurus' and hardcore bodybuilders and not so much online), and of course Insuln.

    note on the Winny: a lot of people don't know that Winny is a Cortisol blocker. they think you get dry and achy joints from it because it 'dries you out' and gets rid of water, but the real reason you get painful joints on it is because its a direct cortisol blocker and cortisol is your bodies natural anti inflammatory that keeps joints inflammation in check.
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  9. #9
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    Quote Originally Posted by GearHeaded View Post
    as far as Cortisol blockers used for bodybuilding purposes , your talking all script drugs , so Winstrol (which you've heard of I'm sure), Cytadren (which works as an anti estrogen on top of being a cortisol suppressant.. this drug is more popular among 'gurus' and hardcore bodybuilders and not so much online), and of course Insuln.

    note on the Winny: a lot of people don't know that Winny is a Cortisol blocker. they think you get dry and achy joints from it because it 'dries you out' and gets rid of water, but the real reason you get painful joints on it is because its a direct cortisol blocker and cortisol is your bodies natural anti inflammatory that keeps joints inflammation in check.
    To add to this: any cortisol blocking past the level of steroids + insulin (mirtazapine) is a baaaaad fucking idea, you will absolutely drag ass and get nothing done workout wise. I have 0 clue how people can function on those drugs.
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    Quote Originally Posted by fiddlesticks View Post
    To add to this: any cortisol blocking past the level of steroids + insulin(mirtazapine) is a baaaaad fucking idea, you will absolutely drag ass and get nothing done workout wise. I have 0 clue how people can function on those drugs.
    yep . if you see any protocols I've done on here that have an 'anti cortisol anti estrogen' phase, you'll see the phase generally lasts no longer then a few weeks. and dosages of things like Cytadren are mild.
    theres no need to seek after constant cortisol suppression (or estrogen suppression for that matter)
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    Quote Originally Posted by GearHeaded View Post
    as far as Cortisol blockers used for bodybuilding purposes , your talking all script drugs , so Winstrol (which you've heard of I'm sure), Cytadren (which works as an anti estrogen on top of being a cortisol suppressant.. this drug is more popular among 'gurus' and hardcore bodybuilders and not so much online), and of course Insuln.

    note on the Winny: a lot of people don't know that Winny is a Cortisol blocker. they think you get dry and achy joints from it because it 'dries you out' and gets rid of water, but the real reason you get painful joints on it is because its a direct cortisol blocker and cortisol is your bodies natural anti inflammatory that keeps joints inflammation in check.
    So running deca with winny on cycle would probably counteract the joint issues??

    I did end up buying some anti cortisol supplements recently though, at this time I'll give anything a try to manage stress
    Working out just aggravates me even more..

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    Quote Originally Posted by EDCG19 View Post
    So running deca with winny on cycle would probably counteract the joint issues??.

    yes to a degree.. some people may find some of my protocols a bit odd , but you could probably search on here and find where I recommend injecting 2000mg of Deca at one time as a single front load dose to running a 6 week cycle of Winsrol.
    of course, running 30mg per day of NPP with your winny cycle will work too
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    keep in mind though that 'masking' anti cortisol effects by simply administering another drug (like deca for joint ease) is not always the answer.. Cortisol does a lot more things in the body then we probably realize , like for example promoting Gluconeogensis , where the liver breaks down amino acids to produce glucose and needed energy for organs like the brain.. this may be "catabolic' in nature, but needed for survival
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    Quote Originally Posted by GearHeaded View Post
    yes to a degree.. some people may find some of my protocols a bit odd , but you could probably search on here and find where I recommend injecting 2000mg of Deca at one time as a single front load dose to running a 6 week cycle of Winsrol.
    of course, running 30mg per day of NPP with your winny cycle will work too
    Yea man, I have been reading up on NPP and looks like its better than deca from what I've been reading. I'm guessing 30mg of NPP is a joke? I'm not sure if it would work at that dose as expected

    How would 1 injection of 2grams deca work? You think it would have the same effects running it long term or you're busting my chain? 2grams in one sitting? Would it work the same way?

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    Quote Originally Posted by GearHeaded View Post
    yep . if you see any protocols I've done on here that have an 'anti cortisol anti estrogen' phase, you'll see the phase generally lasts no longer then a few weeks. and dosages of things like Cytadren are mild.
    theres no need to seek after constant cortisol suppression (or estrogen suppression for that matter)
    cortisol mentally helps alot .. low but manageably low cortisol from ins+gear results in some ass dragging for sure where as a situation where cortisol is very high (meth people,adderall) alot of energy is had. Tanked cortisol from strong anti cort (mirtazapine) results in absolutely nothing getting done.

    A theory I have would be dosing an anti-cort in a dose that would not have systematic effects but only site-injected ones alongside insulin to possibly potentiate it. Mirtazapine definitely has the power to do so.

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    Quote Originally Posted by EDCG19 View Post
    So running deca with winny on cycle would probably counteract the joint issues??
    Not enough to make a difference, respectfully.
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    Every(intelligent)thing works (once aptly and consistently applied)
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    Quote Originally Posted by GearHeaded View Post
    keep in mind though that 'masking' anti cortisol effects by simply administering another drug (like deca for joint ease) is not always the answer.. Cortisol does a lot more things in the body then we probably realize , like for example promoting Gluconeogensis , where the liver breaks down amino acids to produce glucose and needed energy for organs like the brain.. this may be "catabolic' in nature, but needed for survival
    ^^Agreed.
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    Quote Originally Posted by texasmk4
    Nark is like intel, Brilliant inside and awsome outside :-)
    Quote Originally Posted by Narkissos
    Here's a little-known-secret, that most people won't tell you: In the sphere of fitness, everything works.
    Every(intelligent)thing works (once aptly and consistently applied)
    It really is that simple.
    This is the perpetual bodybuilding paradigm
    **No Source Checks**
    Contact Me

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    Quote Originally Posted by EDCG19 View Post
    How would 1 injection of 2grams deca work?

    Insulin increases free testosterone-65382_379820242030695_271376152875105_1495807_325710647_n.jpg
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