
Originally Posted by
GearHeaded
your hypothalamus is shut down and is not producing GHRH at the moment (GHRH = growth hormone releasing hormone .. which is the hormone that stimulates the pituitary to release actual HGH) .. your body was essentially using the MK677 as its GHRH and thus stopped producing it, without shutting down actual HGH release. GHRH shut down, while HGH got upregulated .
your hypothalamus should bounce back though and start producing GHRH again , and thus HGH again .. when you run MK677 for extended periods of time its probably best to take multiple days or even a week off here and there.
being exogenous HGH itself does not directly shut down the hypothalamus (again, MK is essentially replacing what the hypothalamus produces, ie, GHRH) because it doesn't act on the pituitary like MK does , this is not as likely to happen with actual HGH. plus the active life of exiguous HGH is only about 6 hours , where MK is 24 hours .
so with MK , again its best to take days off here and there as you run it