Thread: Pct
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10-04-2007, 04:50 PM #1
Pct
I thought that I had done enough research but obviously not. I know there is always something to learn but what I read was that nolva and clomid were a decent pct for a test and deca cycle. Now im reading that its not and that nolva can atcually be proestro. Any advice?
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10-04-2007, 04:58 PM #2
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10-04-2007, 04:59 PM #3
Oh get ahold of merc. He can give you some good reads on the nolva/prog issue that will help.
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10-04-2007, 05:00 PM #4
Ya, he's the one that brought it up, sent me Tony's link.
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10-04-2007, 05:01 PM #5
I'd help more but I just learned of this yesterday myself
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10-04-2007, 05:09 PM #6
Me too man, maybe someone else will chime in. Thanks though
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Yes Nolva increases PgR ..
People still use nolva for pct .. If I use a 19 nor I wait like about 14 days ( or so) to start my pct ...
Merc.
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10-04-2007, 05:32 PM #8
Theres my boy.
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Nolva is a estrogen antagonist ...
It increases PgR ( progesterone receptors )..
Merc.
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Here is part of one study I posted recently that shows nolva increases PgR..
The PgR gene is an estrogen-regulated gene (34) , so drugs with estrogenic activity will increase its expression. Accordingly, tamoxifen has been shown to increase PgR levels (35) , whereas initial work on primary breast tumors found that a short-acting formulation of ICI 182,780 reduced PgR levels (30) , suggesting that it is devoid of estrogen-agonist activity and may have a different mechanism of action to that of tamoxifen . Additional evidence that ICI 182,780 and tamoxifen have different underlying modes of action comes from studies showing that tamoxifen-resistant tumors remain sensitive to ICI 182,780 treatment in vitro (18 , 19) , in vivo (36 , 37) , and in the clinic (38, 39, 40)
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10-04-2007, 06:13 PM #11
Test and deca cylce. I have nolva and clomid. Do you suggest running nolva clomid armidex and letro?, drop the nolva?, overkill? i can not get hcg or Aromasin . It sounds like I shouldn't run the novla at all while on deca or will the aridex and letro help? Start Nolva 2 weeks after? I wanna do it right!
Last edited by FASTBOATS25; 10-04-2007 at 06:18 PM.
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I am on HRT Though my doc so I dont do pct ..
There are some people that dont have any problem using deca /tren with nolva (although i have heard of lots of peeps that DO have problems when using both of them)..
You could just use letro or adex while your on cycle...
Fot pct if you cant get hcg or aromasin you could look into to using a AI/ SERM ..
Merc.
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